Search Results - "Garcia, Vinícius P."

Reduced arterial vasodilatation in response to hypoxia impairs cerebral and peripheral oxygen delivery in hypertensive men by Fernandes, Igor A., Rocha, Marcos P., Campos, Monique O., Mattos, João D., Mansur, Daniel E., Rocha, Helena N. M., Terra, Paulo A. C., Garcia, Vinícius P., Rocha, Natália G., Secher, Niels H., Nóbrega, Antonio C. L.

“…Key points Hypoxaemia evokes a repertoire of homeostatic adjustments that maintain oxygen supply to organs and tissues including the brain and skeletal…”
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Circulating extracellular microvesicles associated with electronic cigarette use increase endothelial cell inflammation and reduce nitric oxide production by Evanoff, Nicholas G., Dengel, Donald R., Stockelman, Kelly A., Fandl, Hannah, DeSouza, Noah M., Greiner, Jared J., Dufresne, Sheena R., Kotlyar, Michael, Garcia, Vinicius P.

“…The purpose of this study was to determine the effect of circulating microvesicles isolated from chronic electronic (e‐)cigarette users on cultured human…”
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Ascorbic acid prevents stress-induced hypercoagulability in overweight and obese individuals by Rocha, Helena N. M., Velasco, Larissa L., Batista, Gabriel M. S., Storch, Amanda S., Garcia, Vinicius P., Teixeira, Gabriel F., Mentzinger, Juliana, da Nóbrega, Antonio C. L., Rocha, Natália G.

“…Ascorbic acid (AA) may contribute to restoring hemostatic balance after mental stress (MS) in overweight/obese adults. We aimed to determine the effects of AA…”
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Intrathecal fentanyl abolishes the exaggerated blood pressure response to cycling in hypertensive men by Barbosa, Thales C., Vianna, Lauro C., Fernandes, Igor A., Prodel, Eliza, Rocha, Helena N. M., Garcia, Vinicius P., Rocha, Natalia G., Secher, Niels H., Nobrega, Antonio C. L.

“…Key points The increase in blood pressure observed during physical activities is exaggerated in patients with hypertension, exposing them to a higher…”
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AT1R blocker prevents mental stress induced retrograde blood flow in overweight/obese men by Rocha, Helena N. M., Teixeira, Gabriel F., Batista, Gabriel M. S., Storch, Amanda S., Garcia, Vinicius P., Mentzinger, Juliana, Gomes, Erika A. C., Campos, Monique O., Nóbrega, Antonio C. L., Rocha, Natália G.

“…The main goal was to determine the impact of mental stress (MS) on blood flow regulation in overweight/obese men. Fourteen overweight/obese men (27 ± 7 years;…”
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Inflammatory and oxidative responses to disturbed blood flow in hypertensive men by Storch, Amanda S, Rocha, Helena N M, Garcia, Vinicius P, Batista, Gabriel M S, Mattos, João Dario, Campos, Monique O, Nóbrega, Antonio Claudio L, Fernandes, Igor A, Rocha, Natalia G

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Endothelial-derived extracellular vesicles from obese/hypertensive adults increase factors associated with hypertrophy and fibrosis in cardiomyocytes by Fandl, Hannah K, Garcia, Vinicius P, Treuth, John W, Brewster, Lillian M, Greiner, Jared J, Davy, Kevin P, Stauffer, Brian L, Desouza, Christopher A

“…Obesity and hypertension, independently and combined, are associated with increased risk of heart failure and heart failure-related morbidity and mortality…”
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Development of a Hypercoagulable-Hypofibrinolytic State Early After Spinal Cord Injury by Park, Andrew J., Garcia, Vinicius P., Greiner, Jared J., Berry, Auburn R., Cardenas, Hannah L., Wegerson, Kendra N., Stauffer, Brian, DeSouza, Christopher A.

“…To determine whether spinal cord injury (SCI) is associated with adverse changes in coagulation and fibrinolytic factors that underlie thrombogenesis and…”
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Endothelial-derived extracellular vesicles associated with electronic cigarette use impair cerebral microvascular cell function by Cardenas, Hannah L, Evanoff, Nicholas G, Fandl, Hannah K, Berry, Auburn R, Wegerson, Kendra N, Ostrander, Emily I, Greiner, Jared J, Dufresne, Sheena R, Kotlyar, Michael, Dengel, Donald R, DeSouza, Christopher A, Garcia, Vinicius P

“…The aim of this study was to determine the effect of circulating endothelial cell-derived microvesicles (EMVs) isolated from e-cigarette users on human…”
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Endothelin-1-induced endothelial microvesicles impair endothelial cell function by Brewster, L Madden, Garcia, Vinicius P, Levy, Ma'ayan V, Stockelman, Kelly A, Goulding, Anabel, DeSouza, Noah M, Greiner, Jared J, Hijmans, Jamie G, DeSouza, Christopher A

“…The aim of this study was to determine the effects of endothelin-1 (ET-1)-generated endothelial microvesicles (EMVs) on endothelial cell inflammation,…”
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Effects of circulating endothelial microvesicles isolated from adults with obesity on endothelial cell inflammation, apoptosis, and nitric oxide production by Garcia, Vinicius P, Fandl, Hannah K, Hijmans, Jamie G, Berry, Auburn R, Cardenas, Hannah L, Stockelman, Kelly A, DeSouza, Noah M, Treuth, J William, Greiner, Jared J, Park, Andrew J, Stauffer, Brian L, DeSouza, Christopher A

“…Circulating endothelial cell-derived microvesicles (EMVs) have been shown to be elevated with obesity and associated with endothelial dysfunction; however,…”
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Reactive oxygen species play a modulatory role in the hyperventilatory response to poikilocapnic hyperoxia in humans by Fernandes, Igor A., Mattos, João D., Campos, Monique O., Rocha, Marcos P., Mansur, Daniel E., Rocha, Helena M., Garcia, Vinicius P., Alvares, Thiago, Secher, Niels H., Nóbrega, Antonio C.L.

“…Key points The proposed mechanism for the increased ventilation in response to hyperoxia includes a reduced brain CO2–[H+] washout‐induced central…”
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Human brain blood flow and metabolism during isocapnic hyperoxia: the role of reactive oxygen species by Mattos, João D., Campos, Monique O., Rocha, Marcos P., Mansur, Daniel E., Rocha, Helena N. M., Garcia, Vinicius P., Batista, Gabriel, Alvares, Thiago S., Oliveira, Gustavo V., Souza, Mônica V., Videira, Rogério L. R., Rocha, Natalia G., Secher, Niels H., Nóbrega, Antonio C. L., Fernandes, Igor A.

“…Key points It is unknown whether excessive reactive oxygen species (ROS) production drives the isocapnic hyperoxia (IH)‐induced decline in human cerebral blood…”
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Global REACH 2018: dysfunctional extracellular microvesicles in Andean highlander males with excessive erythrocytosis by Brewster, L Madden, Bain, Anthony R, Garcia, Vinicius P, Fandl, Hannah K, Stone, Rachel, DeSouza, Noah M, Greiner, Jared J, Tymko, Michael M, Vizcardo-Galindo, Gustavo A, Figueroa-Mujica, Romulo J, Villafuerte, Francisco C, Ainslie, Philip N, DeSouza, Christopher A

“…High altitude-related excessive erythrocytosis (EE) is associated with increased cardiovascular risk. The experimental aim of this study was to determine the…”
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Hypertension impairs hypoxia-induced angiogenesis in men by Garcia, Vinicius P, Rocha, Helena N M, Rocha, Marcos P, Mattos, João D, Campos, Monique O, Mansur, Daniel E, Secher, Niels H, Nóbrega, Antonio C L, Fernandes, Igor A, Rocha, Natália G

“…The inability of the organism to appropriately respond to hypoxia results in abnormal cell metabolism and function. Hypoxia-induced angiogenesis seems to be…”
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Hypertension impairs hypoxia-induced angiogenesis in men by Garcia, Vinicius P., Rocha, Helena N.M., Rocha, Marcos P., Mattos, João D., Campos, Monique O., Mansur, Daniel E., Secher, Niels H., Nóbrega, Antonio C.L., Fernandes, Igor A., Rocha, Natália G.

“…OBJECTIVE:The inability of the organism to appropriately respond to hypoxia results in abnormal cell metabolism and function. Hypoxia-induced angiogenesis…”
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Differential vasomotor responses to isocapnic hyperoxia: cerebral versus peripheral circulation by Mattos, João D, Campos, Monique O, Rocha, Marcos P, Mansur, Daniel E, Rocha, Helena N M, Garcia, Vinicius P, Rocha, Natalia G, Alvares, Thiago S, Secher, Niels H, Nóbrega, Antonio C L, Fernandes, Igor A

“…Isocapnic hyperoxia (IH) evokes cerebral and peripheral hypoperfusion via both disturbance of redox homeostasis and reduction in nitric oxide (NO)…”
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Disturbed blood flow induces endothelial apoptosis without mobilizing repair mechanisms in hypertension by Rocha, Helena N.M., Garcia, Vinicius P., Batista, Gabriel M.S., Silva, Gustavo M., Mattos, João D., Campos, Monique O., Nóbrega, Antonio C.L., Fernandes, Igor A., Rocha, Natália G.

“…The influence of blood flow disturbances on vascular function, endothelial activation and repair capacity has not been fully elucidated either in physiological…”
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Differential Expression of Vascular-Related MicroRNA in Circulating Endothelial Microvesicles in Adults With Spinal Cord Injury: A Pilot Study by Park, Andrew J, Fandl, Hannah K, Garcia, Vinicius P, Coombs, Geoff B, DeSouza, Noah M, Greiner, Jared J, Barak, Otto F, Mijacika, Tanja, Dujic, Zeljko, Ainslie, Philip N, DeSouza, Christopher A

“…Spinal cord injury (SCI) is associated with an increased risk and prevalence of cardiopulmonary and cerebrovascular disease-related morbidity and mortality…”
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Global REACH 2018: Influence of excessive erythrocytosis on coagulation and fibrinolytic factors in Andean highlanders by DeSouza, Noah M., Brewster, L. Madden, Bain, Anthony R., Garcia, Vinicius P., Stone, Rachel, Stockelman, Kelly A., Greiner, Jared J., Tymko, Michael M., Vizcardo‐Galindo, Gustavo, Figueroa‐Mujica, Romulo J., Villafuerte, Francisco C., Ainslie, Philip N., DeSouza, Christopher A.

“…New Findings What is the central question of this study? Are coagulation and fibrinolytic factors disrupted in Andean highlanders with excessive…”
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