Search Results - "Garcia, Stéphane"

Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions by Olivares, Orianne, Mayers, Jared R., Gouirand, Victoire, Torrence, Margaret E., Gicquel, Tristan, Borge, Laurence, Lac, Sophie, Roques, Julie, Lavaut, Marie-Noëlle, Berthezène, Patrice, Rubis, Marion, Secq, Veronique, Garcia, Stéphane, Moutardier, Vincent, Lombardo, Dominique, Iovanna, Juan Lucio, Tomasini, Richard, Guillaumond, Fabienne, Vander Heiden, Matthew G., Vasseur, Sophie

“…Tissue architecture contributes to pancreatic ductal adenocarcinoma (PDAC) phenotypes. Cancer cells within PDAC form gland-like structures embedded in a…”
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Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma by Guillaumond, Fabienne, Bidaut, Ghislain, Ouaissi, Mehdi, Servais, Stéphane, Gouirand, Victoire, Olivares, Orianne, Lac, Sophie, Borge, Laurence, Roques, Julie, Gayet, Odile, Pinault, Michelle, Guimaraes, Cyrille, Nigri, Jérémy, Loncle, Céline, Lavaut, Marie-Noëlle, Garcia, Stéphane, Tailleux, Anne, Staels, Bart, Calvo, Ezequiel, Tomasini, Richard, Iovanna, Juan Lucio, Vasseur, Sophie

“…The malignant progression of pancreatic ductal adenocarcinoma (PDAC) is accompanied by a profound desmoplasia, which forces proliferating tumor cells to…”
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Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness by Leca, Julie, Martinez, Sébastien, Lac, Sophie, Nigri, Jérémy, Secq, Véronique, Rubis, Marion, Bressy, Christian, Sergé, Arnauld, Lavaut, Marie-Noelle, Dusetti, Nelson, Loncle, Céline, Roques, Julie, Pietrasz, Daniel, Bousquet, Corinne, Garcia, Stéphane, Granjeaud, Samuel, Ouaissi, Mehdi, Bachet, Jean Baptiste, Brun, Christine, Iovanna, Juan L, Zimmermann, Pascale, Vasseur, Sophie, Tomasini, Richard

“…The intratumoral microenvironment, or stroma, is of major importance in the pathobiology of pancreatic ductal adenocarcinoma (PDA), and specific conditions in…”
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Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts by Nicolle, Rémy, Blum, Yuna, Marisa, Laetitia, Loncle, Celine, Gayet, Odile, Moutardier, Vincent, Turrini, Olivier, Giovannini, Marc, Bian, Benjamin, Bigonnet, Martin, Rubis, Marion, Elarouci, Nabila, Armenoult, Lucile, Ayadi, Mira, Duconseil, Pauline, Gasmi, Mohamed, Ouaissi, Mehdi, Maignan, Aurélie, Lomberk, Gwen, Boher, Jean-Marie, Ewald, Jacques, Bories, Erwan, Garnier, Jonathan, Goncalves, Anthony, Poizat, Flora, Raoul, Jean-Luc, Secq, Veronique, Garcia, Stephane, Grandval, Philippe, Barraud-Blanc, Marine, Norguet, Emmanuelle, Gilabert, Marine, Delpero, Jean-Robert, Roques, Julie, Calvo, Ezequiel, Guillaumond, Fabienne, Vasseur, Sophie, Urrutia, Raul, de Reyniès, Aurélien, Dusetti, Nelson, Iovanna, Juan

“…Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine…”
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Immediate or Delayed Transplantation of a Vein Conduit Filled with Nasal Olfactory Stem Cells Improves Locomotion and Axogenesis in Rats after a Peroneal Nerve Loss of Substance by Bonnet, Maxime, Guiraudie-Capraz, Gaëlle, Marqueste, Tanguy, Garcia, Stéphane, Jaloux, Charlotte, Decherchi, Patrick, Féron, François

“…Over the recent years, several methods have been experienced to repair injured peripheral nerves. Among investigated strategies, the use of natural or…”
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Tumor Protein 53-induced Nuclear Protein 1 Is a Major Mediator of p53 Antioxidant Function by CANO, Carla E, GOMMEAUX, Julien, DUSETTI, Nelson J, IOVANNA, Juan L, CARRIER, Alice, PIETRI, Sylvia, CULCASI, Marcel, GARCIA, Stéphane, SEUX, Mylène, BARELIER, Sarah, VASSEUR, Sophie, SPOTO, Rose P, PEBUSQUE, Marie-Josèphe

“…p53 exerts its tumor suppressor function mainly through transcriptional induction of target genes involved in several processes, including cell cycle…”
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Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion by Benyahia, Zohra, Dussault, Nadège, Cayol, Mylène, Sigaud, Romain, Berenguer-Daizé, Caroline, Delfino, Christine, Tounsi, Asma, Garcia, Stéphane, Martin, Pierre-Marie, Mabrouk, Kamel, Ouafik, L'Houcine

“…Tumor- or cancer-associated fibroblasts (TAFs or CAFs) are active players in tumorigenesis and exhibit distinct angiogenic and tumorigenic properties…”
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Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity by Berruyer, Carole, Pouyet, Laurent, Millet, Virginie, Martin, Florent M, LeGoffic, Aude, Canonici, Alexandra, Garcia, Stéphane, Bagnis, Claude, Naquet, Philippe, Galland, Franck

“…Colitis involves immune cell-mediated tissue injuries, but the contribution of epithelial cells remains largely unclear. Vanin-1 is an epithelial ectoenzyme…”
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Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts by Bian, Benjamin, Bigonnet, Martin, Gayet, Odile, Loncle, Celine, Maignan, Aurélie, Gilabert, Marine, Moutardier, Vincent, Garcia, Stephane, Turrini, Olivier, Delpero, Jean‐Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Ouaissi, Mehdi, Secq, Veronique, Poizat, Flora, Nicolle, Rémy, Blum, Yuna, Marisa, Laetitia, Rubis, Marion, Raoul, Jean‐Luc, Bradner, James E, Qi, Jun, Lomberk, Gwen, Urrutia, Raul, Saul, Andres, Dusetti, Nelson, Iovanna, Juan

“…c‐MYC controls more than 15% of genes responsible for proliferation, differentiation, and cellular metabolism in pancreatic as well as other cancers making…”
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Neutrophil extracellular traps are associated with the pathogenesis of diffuse alveolar hemorrhage in murine lupus by Jarrot, Pierre-André, Tellier, Edwige, Plantureux, Lea, Crescence, Lydie, Robert, Stéphane, Chareyre, Corinne, Daniel, Laurent, Secq, Véronique, Garcia, Stéphane, Dignat-George, Françoise, Panicot-Dubois, Laurence, Dubois, Christophe, Kaplanski, Gilles

“…Diffuse alveolar hemorrhage (DAH) is a life-threatening complication of systemic lupus erythematosus (SLE) and systemic vasculitis. Although initially…”
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Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma by Siret, Carole, Dobric, Aurélie, Martirosyan, Anna, Terciolo, Chloé, Germain, Sébastien, Bonier, Renaté, Dirami, Thassadite, Dusetti, Nelson, Tomasini, Richard, Rubis, Marion, Garcia, Stéphane, Iovanna, Juan, Lombardo, Dominique, Rigot, Véronique, André, Frédéric

“…Background: Pancreatic ductal adenocarcinoma (PDAC) is characterised by an extensive tissue invasion and an early formation of metastasis. Alterations in the…”
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Functional recovery after peripheral nerve injury and implantation of a collagen guide by Alluin, Olivier, Wittmann, Catherine, Marqueste, Tanguy, Chabas, Jean-François, Garcia, Stéphane, Lavaut, Marie-Noëlle, Guinard, Didier, Feron, François, Decherchi, Patrick

“…Abstract Although surgery techniques improved over the years, the clinical results of peripheral nerve repair remain unsatisfactory. In the present study, we…”
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Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer by Ghiringhelli, François, Bibeau, Frederic, Greillier, Laurent, Fumet, Jean-David, Ilie, Alis, Monville, Florence, Laugé, Caroline, Catteau, Aurélie, Boquet, Isabelle, Majdi, Amine, Morgand, Erwan, Oulkhouir, Youssef, Brandone, Nicolas, Adam, Julien, Sbarrato, Thomas, Kassambara, Alboukadel, Fieschi, Jacques, Garcia, Stéphane, Lepage, Anne Laure, Tomasini, Pascale, Galon, Jérôme

“…Anti-PD-1 and PD-L1 antibodies (mAbs) are approved immunotherapy agents to treat metastatic non-small cell lung cancer (NSCLC) patients. Only a minority of…”
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Best imaging signs identified by radiomics could outperform the model: application to differentiating lung carcinoid tumors from atypical hamartomas by Habert, Paul, Decoux, Antoine, Chermati, Lilia, Gibault, Laure, Thomas, Pascal, Varoquaux, Arthur, Le Pimpec-Barthes, Françoise, Arnoux, Armelle, Juquel, Loïc, Chaumoitre, Kathia, Garcia, Stéphane, Gaubert, Jean-Yves, Duron, Loïc, Fournier, Laure

“…Objectives Lung carcinoids and atypical hamartomas may be difficult to differentiate but require different treatment. The aim was to differentiate these tumors…”
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Infection with hepatitis E virus in kidney transplant recipients in southeastern France by Moal, Valérie, Legris, Tristan, Burtey, Stéphane, Morange, Sophie, Purgus, Raj, Dussol, Bertrand, Garcia, Stéphane, Motte, Anne, Gérolami, René, Berland, Yvon, Colson, Philippe

“…Hepatitis E virus (HEV) is an emerging cause of acute hepatitis in Europe, particularly in southern France, and HEV is a new causative agent of chronic…”
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Homotypic cell cannibalism, a cell‐death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer by Cano, Carla E., Sandí, María José, Hamidi, Tewfik, Calvo, Ezequiel L., Turrini, Olivier, Bartholin, Laurent, Loncle, Céline, Secq, Véronique, Garcia, Stéphane, Lomberk, Gwen, Kroemer, Guido, Urrutia, Raul, Iovanna, Juan L.

“…Pancreatic adenocarcinoma (PDAC) is an extremely deadly disease for which all treatments available have failed to improve life expectancy significantly. This…”
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Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis by Cano, Carla E, Hamidi, Tewfik, Garcia, Maria Noé, Grasso, Daniel, Loncle, Céline, Garcia, Stéphane, Calvo, Ezequiel, Lomberk, Gwen, Dusetti, Nelson, Bartholin, Laurent, Urrutia, Raul, Iovanna, Juan L

“…Nuclear protein 1 (Nupr1) is a major factor in the cell stress response required for Kras(G12D)-driven formation of pancreatic intraepithelial neoplastic…”
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Anti-proliferative and anti-secretory effects of everolimus on human pancreatic neuroendocrine tumors primary cultures: is there any benefit from combination with somatostatin analogs? by Mohamed, Amira, Romano, David, Saveanu, Alexandru, Roche, Catherine, Albertelli, Manuela, Barbieri, Federica, Brue, Thierry, Niccoli, Patricia, Delpero, Jean-Robert, Garcia, Stephane, Ferone, Diego, Florio, Tullio, Moutardier, Vincent, Poizat, Flora, Barlier, Anne, Gerard, Corinne

“…Therapeutic management of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is challenging. The mammalian target of rapamycin (mTOR) inhibitor everolimus…”
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Colitis and Colitis-Associated Cancer Are Exacerbated in Mice Deficient for Tumor Protein 53-Induced Nuclear Protein 1 by Gommeaux, Julien, Cano, Carla, Garcia, Stéphane, Gironella, Meritxell, Pietri, Sylvia, Culcasi, Marcel, Pébusque, Marie-Josèphe, Malissen, Bernard, Dusetti, Nelson, Iovanna, Juan, Carrier, Alice

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity by Taieb, David, Roignot, Julie, André, Frédéric, Garcia, Stéphane, Masson, Bénédicte, Pierres, Anne, Iovanna, Juan-Lucio, Soubeyran, Philippe

“…The poor prognosis of pancreatic cancer is due to rapid locoregional invasion, the early development of metastases, and the limited efficacy of current…”
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