Search Results - "Garcia, Jesus Beltran"

Development of Novel Lipid Nanoparticles and Virus-like Particles for In Vivo Engineering of Immune Cells for Targeted Cancer Therapy by Beltran-Garcia, Jesus, Han, Sangwoo, Perez, Barbara S., Gunn, Jonathan, Kwon, Ester, Kaufman, Dan

“…Recent progress in genetic and cellular engineering has revolutionized medicine and cancer care, offering new avenues for effective treatments and potential…”
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Extracellular histones induce endothelial pyroptosis through oxidative stress mechanisms leading to severe phenotypes in sepsis by Beltran-Garcia, Jesus, Osca-Verdegal, Rebeca, Nacher-Sendra, Elena, Novella, Susana, Hermenegildo, Carlos, Pallardó, Federico V., García-Giménez, José Luis

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Role of microRNAs As Biomarkers in Sepsis-Associated Encephalopathy by Osca-Verdegal, Rebeca, Beltrán-García, Jesús, Pallardó, Federico V., García-Giménez, José Luis

“…Sepsis-associated encephalopathy (SAE) is a neurological complication of sepsis, characterized by brain dysfunction without any direct central nervous system…”
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Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease Progression by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Pallardó, Federico V., Ferreres, José, Rodríguez, María, Mulet, Sandra, Sanchis-Gomar, Fabian, Carbonell, Nieves, García-Giménez, José Luis

“…Since the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak emerged, countless efforts are being made worldwide to understand the molecular…”
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Epigenetic IVD Tests for Personalized Precision Medicine in Cancer by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Mena-Mollá, Salvador, García-Giménez, José Luis

“…Epigenetic alterations play a key role in the initiation and progression of cancer. Therefore, it is possible to use epigenetic marks as biomarkers for…”
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The Endothelial Glycocalyx and Neonatal Sepsis by Fatmi, Ahlam, Saadi, Wiam, Beltrán-García, Jesús, García-Giménez, José Luis, Pallardó, Federico V

“…Sepsis carries a substantial risk of morbidity and mortality in newborns, especially preterm-born neonates. Endothelial glycocalyx (eGC) is a carbohydrate-rich…”
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Challenges in the analysis of epigenetic biomarkers in clinical samples by García-Giménez, José Luis, Mena-Mollá, Salvador, Beltrán-García, Jesús, Sanchis-Gomar, Fabian

“…Epigenetic modifications represent an interesting landscape which can describe relevant features of human disease. Epigenetic biomarkers show several…”
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Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Nacher-Sendra, Elena, Pallardó, Federico V, García-Giménez, José Luis

“…Sepsis is a life-threatening condition that occurs when the body responds to an infection that damages it is own tissues. The major problem in sepsis is rapid,…”
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The Intricate Role of Non-Coding RNAs in Sepsis-Associated Disseminated Intravascular Coagulation by Cánovas-Cervera, Irene, Nacher-Sendra, Elena, Osca-Verdegal, Rebeca, Dolz-Andrés, Enric, Beltrán-García, Jesús, Rodríguez-Gimillo, María, Ferrando-Sánchez, Carolina, Carbonell, Nieves, García-Giménez, José Luis

“…Disseminated Intravascular Coagulation (DIC) is a type of tissue and organ dysregulation in sepsis, due mainly to the effect of the inflammation on the…”
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Validation of circulating histone detection by mass spectrometry for early diagnosis, prognosis, and management of critically ill septic patients by García-Giménez, José Luis, García-López, Eva, Mena-Mollá, Salvador, Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Nacher-Sendra, Elena, Aguado-Velasco, Carmen, Casabó-Vallés, Germán, Romá-Mateo, Carlos, Rodriguez-Gimillo, María, Antúnez, Oreto, Ferreres, José, Pallardó, Federico V, Carbonell, Nieves

“…As leading contributors to worldwide morbidity and mortality, sepsis and septic shock are considered a major global health concern. Proactive biomarker…”
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DNA Methylation Analysis to Unravel Altered Genetic Pathways Underlying Early Onset and Late Onset Neonatal Sepsis. A Pilot Study by Lorente-Pozo, Sheila, Navarrete, Paula, Garzón, María José, Lara-Cantón, Inmaculada, Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Mena-Mollá, Salvador, García-López, Eva, Vento, Máximo, Pallardó, Federico V, García-Giménez, José Luis

“…Neonatal sepsis is a systemic condition widely affecting preterm infants and characterized by pro-inflammatory and anti-inflammatory responses. However, its…”
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Alterations in leukocyte DNA methylome are associated to immunosuppression in severe clinical phenotypes of septic patients by Beltrán-García, Jesús, Casabó-Vallés, Germán, Osca-Verdegal, Rebeca, Navarrete-López, Paula, Rodriguez-Gimillo, María, Nacher-Sendra, Elena, Ferrando-Sánchez, Carolina, García-López, Eva, Pallardó, Federico V, Carbonell, Nieves, Mena-Mollá, Salvador, García-Giménez, José Luis

“…Sepsis patients experience a complex interplay of host pro- and anti-inflammatory processes which compromise the clinical outcome. Despite considering the…”
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Comparative Analysis of Chromatin-Delivered Biomarkers in the Monitoring of Sepsis and Septic Shock: A Pilot Study by Beltrán-García, Jesús, Manclús, Juan J., García-López, Eva M., Carbonell, Nieves, Ferreres, José, Rodríguez-Gimillo, María, Garcés, Concepción, Pallardó, Federico V., García-Giménez, José L., Montoya, Ángel, Romá-Mateo, Carlos

“…Sepsis management remains one of the most important challenges in modern clinical practice. Rapid progression from sepsis to septic shock is practically…”
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Epigenetic biomarkers for human sepsis and septic shock: insights from immunosuppression by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Romá-Mateo, Carlos, Carbonell, Nieves, Ferreres, José, Rodríguez, María, Mulet, Sandra, García-López, Eva, Pallardó, Federico V, García-Giménez, José Luis

“…Sepsis is a life-threatening condition that occurs when the body responds to an infection damaging its own tissues. Sepsis survivors sometimes suffer from…”
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Extracellular Histones Activate Endothelial NLRP3 Inflammasome and are Associated with a Severe Sepsis Phenotype by Garcia, Jesus Beltran, Verdegal, Rebeca Osca, Cremades, Daniel Perez, Novella, Susana, Hermenegildo, Carlos, Pallardo, Federico V, Gimenez, Jose Luis Garcia

“…Introduction: Circulating extracellular histones acquire relevance as cytotoxic mediators in sepsis. Extracellular histones act as damage-associated molecular…”
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Histone Citrullination Mediates a Protective Role in Endothelium and Modulates Inflammation by Osca-Verdegal, Rebeca, Beltrán-García, Jesús, Paes, Ana B, Nacher-Sendra, Elena, Novella, Susana, Hermenegildo, Carlos, Carbonell, Nieves, García-Giménez, José Luis, Pallardó, Federico V

“…NETosis is a key host immune process against a pathogenic infection during innate immune activation, consisting of a neutrophil "explosion" and, consequently,…”
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Use of Circular RNAs in Diagnosis, Prognosis and Therapeutics of Renal Cell Carcinoma by Osca-Verdegal, Rebeca, Beltrán-García, Jesús, Górriz, José Luis, Martínez Jabaloyas, José María, Pallardó, Federico V., García-Giménez, José Luis

“…Renal cell carcinoma is the most common type of kidney cancer, representing 90% of kidney cancer diagnoses, and the deadliest urological cancer. While the…”
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Characterization of Early Peripheral Immune Responses in Patients with Sepsis and Septic Shock by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Jávega, Beatriz, Herrera, Guadalupe, O'Connor, José-Enrique, García-López, Eva, Casabó-Vallés, Germán, Rodriguez-Gimillo, María, Ferreres, José, Carbonell, Nieves, Pallardó, Federico V, García-Giménez, José Luis

“…(1) Background: Sepsis is a life-threatening condition caused by an abnormal host response to infection that produces altered physiological responses causing…”
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Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials by Victoria-Escandell, Alejandro, Ibañez-Cabellos, José Santiago, de Cutanda, Sergio Bañuls-Sánchez, Berenguer-Pascual, Ester, Beltrán-García, Jesús, García-López, Eva, Pallardó, Federico V., García-Giménez, José Luis, Pallarés-Sabater, Antonio, Zarzosa-López, Ignacio, Monterde, Manuel

“…Human dental pulp stem cells (HDPSCs) are of special relevance in future regenerative dental therapies. Characterizing cytotoxicity and genotoxicity produced…”
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Sepsis and Coronavirus Disease 2019: Common Features and Anti-Inflammatory Therapeutic Approaches by Beltrán-García, Jesús, Osca-Verdegal, Rebeca, Pallardó, Federico V., Ferreres, José, Rodríguez, María, Mulet, Sandra, Ferrando-Sánchez, Carolina, Carbonell, Nieves, García-Giménez, José Luis

“…Great efforts are being made worldwide to identify the specific clinical characteristics of infected critically ill patients that mediate the associated…”
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