Search Results - "Garcia, J.G.N."

Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: Role of receptor transactivation by Singleton, P.A., Lingen, M.W., Fekete, M.J., Garcia, J.G.N., Moss, J.

“…Angiogenesis or the formation of new blood vessels is important in the growth and metastatic potential of various cancers. Therefore, agents that inhibit…”
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242: Pre-B-Cell Colony Enhancing Factor (PBEF) Is a Novel target in Hypoxia-Induced Murine Pulmonary Hypertension by Machado, R.F, Moreno-Vinasco, L, Zaidi, R, Sammani, S, Garcia, J.G.N

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Myosin Light Chain Kinase (MYLK) Variants that Confer Increased Risk of Sepsis and Acute Lung Injury are Associated with Asthma and Associated Phenotypes by Gao, L, Grant, A, Chi, P, Gao, P, Stockton, M, Watson, H, Hansel, N.N, Diette, G, Dunston, G, Mathias, R.A, Togias, A, Brower, R, Sevransky, J, Maloney, J.P, Moss, M, Shanholtz, C, Garcia, J.G.N, Beaty, T.H, Barnes, K.C

“…Asthma is a heritable trait characterized by lower airway smooth muscle contraction and inflammation…”
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306 POSTER Methylnaltrexone-induced receptor tyrosine phosphatase mu (RPTP mu) activation regulates inhibition of VEGF-induced angiogenesis by Moss, J, Singleton, P.A, Garcia, J.G.N

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Preclinical Model to Predict Anti-Leukemic Activity of Busulfan and Irradiation by Patel, P.R, Mahmud, D, Zhan, W, Zhou, T, Weichselbaum, R.R, Garcia, J.G.N, Rondelli, D

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Differential elastic responses to barrier-altering agonists in two types of human lung endothelium by Viswanathan, P., Ephstein, Y., Garcia, J.G.N., Cho, M., Dudek, S.M.

“…Vascular integrity is primarily determined by endothelial cell (EC) cytoskeletal structure that is differentially regulated by various stimuli. In this study,…”
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The Significant Role of c-Abl Kinase in Barrier Altering Agonists-mediated Cytoskeletal Biomechanics by Wang, X., Wang, L., Garcia, J. G. N., Dudek, S. M., Shekhawat, G. S., Dravid, V. P.

“…Exploration of human pulmonary artery endothelial cell (EC) as a prototypical biomechanical system has important pathophysiologic relevance because this cell…”
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FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl by WANG, L, CHIANG, E. T, SIMMONS, J. T, GARCIA, J. G. N, DUDEK, S. M

“…Strategies to improve pulmonary endothelial barrier function are needed to reverse the devastating effects of vascular leak in acute respiratory distress…”
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Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis by Man, M, Close, S L, Shaw, A D, Bernard, G R, Douglas, I S, Kaner, R J, Payen, D, Vincent, J-L, Fossceco, S, Janes, J M, Leishman, A G, O'Brien, L, Williams, M D, Garcia, J G N

“…Management of severe sepsis, an acute illness with high morbidity and mortality, suffers from the lack of effective biomarkers and largely empirical…”
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HABP2 is a Novel Regulator of Vascular Integrity by Mambetsariev, N., Mirzapoiazova, T., Mambetsariev, B., Sammani, S., Lennon, F.E., Garcia, J.G.N., Singleton, P.A.

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Gene Transcripts of Peripheral Blood as Potential Biomarkers for Allergic Changes in Upper Airways by Grigoryev, D.N., Ma, S.F., Ye, S.Q., Garcia, J.G.N., Barnes, K.C.

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A Reevaluation of Evans Blue Dye as a Marker of Albumin Clearance in Mouse Models of Acute Lung Injury by Sammani, S., Moitra, J., Garcia, J.G.N.

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Role of Rac Guanosine Triphosphatase in Simvastatin-Mediated Endothelial Cell Signaling by Jacobson, J.R., Chen, W., Garcia, J.G.N.

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Novel Mechanism of Prostaglandin E 2 -Mediated Endothelial Cell Barrier Enhancement: Role of Epcr, S1P 1 Receptor, Epac, Rap1, Af-6, and Profilin by Singleton, P.A., Dore, S., Garcia, J.G.N.

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Novel Mechanism of Prostaglandin E2-Mediated Endothelial Cell Barrier Enhancement: Role of Epcr, S1P1 Receptor, Epac, Rap1, Af-6, and Profilin by Singleton, P.A., Dore, S., Garcia, J.G.N.

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Role of Caspase Activation and Apoptosis in Sphingosine 1-P-Induced Human Endothelial Cell Angiogenesis and Tube Maturation by McGillem, L. Linz, Garcia, J.G.N.

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Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P 1 receptor by Dudek, S.M., Camp, S.M., Chiang, E.T., Singleton, P.A., Usatyuk, P.V., Zhao, Y., Natarajan, V., Garcia, J.G.N.

“…Novel therapeutic strategies are needed to reverse the loss of endothelial cell (EC) barrier integrity that occurs during inflammatory disease states such as…”
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Protective effects of oxidized phospholipids on ventilator-induced lung injury by Birukova, A.A., Nonas, S.A., Miller, I., Chatchavalvanich, S., Garcia, J.G.N., Birukov, K.G.

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80 POSTER Methylnaltrexone potentiates the effects of 5-fluorouracil (5-FU) and Bevacizumab on inhibition of VEGF-induced endothelial cell proliferation and migration by Moss, J., Singleton, P.A., Garcia, J.G.N.

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Signal Transduction and Gene Expression in Magnitude-Dependent Mechanochemical Regulation of Lung Endothelial Barrier by Chatchavalvanich, S., Birukova, A.A., Garcia, J.G.N., Birukov, K.G.

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