Search Results - "Garcia, Charles A."

North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13 by Small, Kent W., MD, DeLuca, Adam P., PhD, Whitmore, S. Scott, PhD, Rosenberg, Thomas, MD, Silva-Garcia, Rosemary, MD, Udar, Nitin, PhD, Puech, Bernard, MD, Garcia, Charles A., MD, Rice, Thomas A., MD, Fishman, Gerald A., MD, Héon, Elise, MD, Folk, James C., MD, Streb, Luan M., BA, Haas, Christine M., BA, Wiley, Luke A., PhD, Scheetz, Todd E., PhD, Fingert, John H., MD, PhD, Mullins, Robert F., PhD, Tucker, Budd A., PhD, Stone, Edwin M., MD, PhD

“…Purpose To identify specific mutations causing North Carolina macular dystrophy (NCMD). Design Whole-genome sequencing coupled with reverse transcription…”
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A dominant mutation in hexokinase 1 (HK1) causes retinitis pigmentosa by Sullivan, Lori S, Koboldt, Daniel C, Bowne, Sara J, Lang, Steven, Blanton, Susan H, Cadena, Elizabeth, Avery, Cheryl E, Lewis, Richard A, Webb-Jones, Kaylie, Wheaton, Dianna H, Birch, David G, Coussa, Razck, Ren, Huanan, Lopez, Irma, Chakarova, Christina, Koenekoop, Robert K, Garcia, Charles A, Fulton, Robert S, Wilson, Richard K, Weinstock, George M, Daiger, Stephen P

“…To identify the cause of retinitis pigmentosa (RP) in UTAD003, a large, six-generation Louisiana family with autosomal dominant retinitis pigmentosa (adRP). A…”
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A Preclinical Safety Study of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells for Macular Degeneration by Mazzilli, John L, Snook, Joshua D, Simmons, Ken, Domozhirov, Aleksey Y, Garcia, Charles A, Wetsel, Rick A, Zsigmond, Eva M, Westenskow, Peter D

“…Age-related macular degeneration (AMD) is a common disease trending towards epidemic proportions and is a leading cause of irreversible vision loss in people…”
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Pearls of Elschnig by K Foutch, Brian, A Garcia, Charles, S Ferguson, Amy

“…This is a Photo Essay and does not contain an abstract…”
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ACE2 gene transfer ameliorates vasoreparative dysfunction in CD34+ cells derived from diabetic older adults by Joshi, Shrinidh, Montes de Oca, Ildamaris, Maghrabi, Ahmad, Lopez-Yang, Christine, Quiroz-Olvera, Julio, Garcia, Charles A, Jarajapu, Yagna Prasada Rao

“…Diabetes increases the risk for ischemic vascular diseases, which is further elevated in older adults. Bone marrow-derived hematopoietic CD34+ stem/progenitor…”
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The role of telomerase reverse transcriptase in the mitochondrial protective functions of Angiotensin-(1–7) in diabetic CD34+ cells by Jahan, Jesmin, Joshi, Shrinidh, Oca, Ildamaris Montes de, Toelle, Andrew, Lopez-Yang, Christine, Chacon, Carmen V., Beyer, Andreas M., Garcia, Charles A., Jarajapu, Yagna PR

“…[Display omitted] Angiotensin (Ang)-(1–7) stimulates vasoprotective functions of diabetic (DB) CD34+ hematopoietic stem/progenitor cells partly by decreasing…”
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Complement Receptor 1 (CR1/CD35)-expressing retinal pigment epithelial cells as a potential therapy for age-related macular degeneration by Simmons, Ken T., Mazzilli, John L., Mueller-Ortiz, Stacey L., Domozhirov, Aleksey Y., Garcia, Charles A., Zsigmond, Eva M., Wetsel, Rick A.

“…•CR1, a membrane-bound complement inhibitor, shows little to no expression on RPE.•Stable transfection produced a CR1-expressing ARPE19 line.•CR1-expressing…”
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Prevalence of Disease-Causing Mutations in Families with Autosomal Dominant Retinitis Pigmentosa: A Screen of Known Genes in 200 Families by Sullivan, Lori S, Bowne, Sara J, Birch, David G, Hughbanks-Wheaton, Dianna, Heckenlively, John R, Lewis, Richard Alan, Garcia, Charles A, Ruiz, Richard S, Blanton, Susan H, Northrup, Hope, Gire, Anisa I, Seaman, Robyn, Duzkale, Hatice, Spellicy, Catherine J, Zhu, Jingya, Shankar, Suma P, Daiger, Stephen P

“…To survey families with clinical evidence of autosomal dominant retinitis pigmentosa (adRP) for mutations in genes known to cause adRP. Two hundred adRP…”
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Persistent unilateral central serous chorioretinopathy in a breastfeeding woman by Lopez-Yang, Christine Elizabeth, Garcia, Charles A

“…A 40-year-old woman presented with blurred vision and floaters in her right eye for the past 7 months. The patient was in the sixth month of pregnancy at onset…”
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Derivation and characterization of the human embryonic stem cell line CR-4: Differentiation to human retinal pigment epithelial cells by Mazzilli, John L., Domozhirov, Aleksey Y., Mueller-Ortiz, Stacey L., Garcia, Charles A., Wetsel, Rick A., Zsigmond, Eva M.

“…The CR-4 human embryonic stem cell line was derived from the inner cell mass of a developing blastocyst. This cell line has been adapted to grow in feeder-free…”
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Retinal lesions as clues to disseminated bacterial and candidal infections: frequency, natural history, and etiology by Rodríguez-Adrián, Libsen J, King, Robert T, Tamayo-Derat, Luis G, Miller, John W, Garcia, Charles A, Rex, John H

“…Invasive bacterial and candidal infections are known to involve the retina, but the natural history of the retinal lesions and the utility of ophthalmologic…”
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Biodegradation and tissue reaction to intravitreous biodegradable poly(D,L-lactic-co-glycolic)acid microspheres by Giordano, G G, Chevez-Barrios, P, Refojo, M F, Garcia, C A

“…We studied the biodegradation of and the tissue reaction to microspheres of 50:50 poly(D,L-lactic-co-glycolic)acid (PLGA) (viscosity-average MW: 3000 d),…”
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Central serous chorioretinopathy after blunt trauma by Ponce, Claudia Maria Prospero, Mohidat, Hasan M, Garcia, Charles A

“…The authors report a case of a 46-year-old Hispanic male with central serous chorioretinopathy (CSC) following blunt trauma to the left eye. The patient…”
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Comparison of the modified Early Treatment Diabetic Retinopathy Study and mild macular grid laser photocoagulation strategies for diabetic macular edema by Fong, Donald S, Strauber, Samara F, Aiello, Lloyd Paul, Beck, Roy W, Callanan, David G, Danis, Ronald P, Davis, Matthew D, Feman, Stephen S, Ferris, Frederick, Friedman, Scott M, Garcia, Charles A, Glassman, Adam R, Han, Dennis P, Le, Darma, Kollman, Craig, Lauer, Andreas K, Recchia, Franco M, Solomon, Sharon D

“…To compare 2 laser photocoagulation techniques for treatment of diabetic macular edema: the modified Early Treatment Diabetic Retinopathy Study (ETDRS)…”
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Aicardi Syndrome in Monozygotic Twins by Pons, Mauricio E., Garcia, Charles A.

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Squalamine lactate for exudative age-related macular degeneration by Connolly, Brian, Desai, Avinash, Garcia, Charles A, Thomas, Edgar, Gast, Michael J

“…Squalamine lactate inhibits angiogenesis by a long-lived, intracellular mechanism of action. The drug is taken up into activated endothelial cells through…”
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Abstract P241: Involvement of Mitochondrial Telomerase Reverse Transcriptase in the Restoration of Nitric Oxide Levels by Angiotensin-(1-7) in the Dysfunctional Diabetic CD34 + Cells by Joshi, Shrinidh, Gomez, Sam, Cantu, Wendy, Quiroz, Julio, Beyer, Andreas, Garcia, Charles A, Jarajapu, Yagna P

“…Abstract only Telomerase reverse transcriptase (TERT) has been shown to translocate to mitochondria (mtTERT), and decrease the generation of mitochondrial…”
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Proton beam irradiation of subfoveal choroidal neovascularisation in age-related macular degeneration by FLAXEL, C. J, FRIEDRICHSEN, E. J, SMITH, J. O, OEINCK, S. C, BLACHARSKI, P. A, GARCIA, C. A, CHU, H. H

“…To assess the safety and potential toxicity of proton beam radiation in the treatment of subfoveal choroidal neovascular membrane (CNVM) due to age-related…”
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Manufacture and characterization of poly(α-hydroxy ester) thin films as temporary substrates for retinal pigment epithelium cells by Thomson, Robert C., Giordano, Giovanni G., Collier, Joel H., Ishaug, Susan L., Mikos, Antonios G., Lahiri-Munir, Devjani, Garcia, Charles A.

“…For many disorders of the retinal pigment epithelium (RPE) for which there are no effective treatments, transplantation of RPE cells may provide a viable means…”
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North Carolina macular dystrophy (MCDR1) in Texas by Small, K W, Garcia, C A, Gallardo, G, Udar, N, Yelchits, S

“…To map the gene responsible for causing a macular degeneration in a Texan family that appears clinically similar to the North Carolina macular dystrophy…”
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