Search Results - "Garcia, Benjamin"

Comprehensive Catalog of Currently Documented Histone Modifications by Zhao, Yingming, Garcia, Benjamin A

“…Modern techniques in molecular biology, genomics, and mass spectrometry-based proteomics have identified a large number of novel histone posttranslational…”
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Recognizing Hispanic and Latinx Analytical Scientists by Garcia, Benjamin A

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Central Bank Independence at Low Interest Rates by GARCÍA, BENJAMÍN, SKAPERDAS, ARSENIOS

“…Abstract We create a new measure of the political pressure faced by the Federal Reserve based on the analysis of transcripts of the Chairs' testimonies to…”
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High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells by He, Chongsheng, Sidoli, Simone, Warneford-Thomson, Robert, Tatomer, Deirdre C., Wilusz, Jeremy E., Garcia, Benjamin A., Bonasio, Roberto

“…Interactions between noncoding RNAs and chromatin proteins play important roles in gene regulation, but the molecular details of most of these interactions are…”
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Quantitative Proteomic Analysis of Histone Modifications by Huang, He, Lin, Shu, Garcia, Benjamin A, Zhao, Yingming

“…A look at the quantitative proteomic analysis of histone modifications is presented. detection of histone PTMs with high sequence coverage and sensitivity and…”
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NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming by Kuo, Alex J., Cheung, Peggie, Chen, Kaifu, Zee, Barry M., Kioi, Mitomu, Lauring, Josh, Xi, Yuanxin, Park, Ben Ho, Shi, Xiaobing, Garcia, Benjamin A., Li, Wei, Gozani, Or

“…The histone lysine methyltransferase NSD2 (MMSET/WHSC1) is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent…”
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A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation by Laurent, Benoit, Ruitu, Lv, Murn, Jernej, Hempel, Kristina, Ferrao, Ryan, Xiang, Yang, Liu, Shichong, Garcia, Benjamin A., Wu, Hao, Wu, Feizhen, Steen, Hanno, Shi, Yang

“…Lysine-specific demethylase 1 (LSD1) has been reported to repress and activate transcription by mediating histone H3K4me1/2 and H3K9me1/2 demethylation,…”
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Bifunctional Peptide Nanofibrils for Targeted Protein Degradation by Lin, Zongtao, Garcia, Benjamin A., Lv, Dongwen

“…Proteolysis targeting chimera (PROTAC) is a state‐of‐the‐art technology for ablating undruggable targets. A PROTAC degrader achieves targeted protein…”
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Critical Role of Histone Turnover in Neuronal Transcription and Plasticity by Maze, Ian, Wenderski, Wendy, Noh, Kyung-Min, Bagot, Rosemary C., Tzavaras, Nikos, Purushothaman, Immanuel, Elsässer, Simon J., Guo, Yin, Ionete, Carolina, Hurd, Yasmin L., Tamminga, Carol A., Halene, Tobias, Farrelly, Lorna, Soshnev, Alexey A., Wen, Duancheng, Rafii, Shahin, Birtwistle, Marc R., Akbarian, Schahram, Buchholz, Bruce A., Blitzer, Robert D., Nestler, Eric J., Yuan, Zuo-Fei, Garcia, Benjamin A., Shen, Li, Molina, Henrik, Allis, C. David

“…Turnover and exchange of nucleosomal histones and their variants, a process long believed to be static in post-replicative cells, remains largely unexplored in…”
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Asymmetrically Modified Nucleosomes by Voigt, Philipp, LeRoy, Gary, Drury, William J., III, Zee, Barry M, Son, Jinsook, Beck, David B, Young, Nicolas L, Garcia, Benjamin A, Reinberg, Danny

“…Mononucleosomes, the basic building blocks of chromatin, contain two copies of each core histone. The associated posttranslational modifications regulate…”
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Human chimeric antigen receptor macrophages for cancer immunotherapy by Klichinsky, Michael, Ruella, Marco, Shestova, Olga, Lu, Xueqing Maggie, Best, Andrew, Zeeman, Martha, Schmierer, Maggie, Gabrusiewicz, Konrad, Anderson, Nicholas R., Petty, Nicholas E., Cummins, Katherine D., Shen, Feng, Shan, Xinhe, Veliz, Kimberly, Blouch, Kristin, Yashiro-Ohtani, Yumi, Kenderian, Saad S., Kim, Miriam Y., O’Connor, Roddy S., Wallace, Stephen R., Kozlowski, Miroslaw S., Marchione, Dylan M., Shestov, Maksim, Garcia, Benjamin A., June, Carl H., Gill, Saar

“…Chimeric antigen receptor (CAR) T cell therapy has shown promise in hematologic malignancies, but its application to solid tumors has been challenging 1 – 4 …”
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Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling by Runkle, Kristin B., Kharbanda, Akriti, Stypulkowski, Ewa, Cao, Xing-Jun, Wang, Wei, Garcia, Benjamin A., Witze, Eric S.

“…Inappropriate activation of the receptor tyrosine kinase EGFR contributes to a variety of human malignancies. Here we show a mechanism to induce vulnerability…”
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SnapShot: Histone Modifications by Huang, He, Sabari, Benjamin R., Garcia, Benjamin A., Allis, C. David, Zhao, Yingming

“…Histone proteins are decorated by a variety of protein posttranslational modifications called histone marks that modulate chromatin structure and function,…”
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Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation by Dorighi, Kristel M., Swigut, Tomek, Henriques, Telmo, Bhanu, Natarajan V., Scruggs, Benjamin S., Nady, Nataliya, Still, Christopher D., Garcia, Benjamin A., Adelman, Karen, Wysocka, Joanna

“…Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at lysine 27 (H3K27ac) are correlated with transcriptionally engaged enhancer…”
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Comprehensive glycoproteomics shines new light on the complexity and extent of glycosylation in archaea by Schulze, Stefan, Pfeiffer, Friedhelm, Garcia, Benjamin A, Pohlschroder, Mechthild

“…Glycosylation is one of the most complex posttranslational protein modifications. Its importance has been established not only for eukaryotes but also for a…”
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The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape by Weinberg, Daniel N., Papillon-Cavanagh, Simon, Chen, Haifen, Yue, Yuan, Chen, Xiao, Rajagopalan, Kartik N., Horth, Cynthia, McGuire, John T., Xu, Xinjing, Nikbakht, Hamid, Lemiesz, Agata E., Marchione, Dylan M., Marunde, Matthew R., Meiners, Matthew J., Cheek, Marcus A., Keogh, Michael-Christopher, Bareke, Eric, Djedid, Anissa, Harutyunyan, Ashot S., Jabado, Nada, Garcia, Benjamin A., Li, Haitao, Allis, C. David, Majewski, Jacek, Lu, Chao

“…Enzymes that catalyse CpG methylation in DNA, including the DNA methyltransferases 1 (DNMT1), 3A (DNMT3A) and 3B (DNMT3B), are indispensable for mammalian…”
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Accelerating the Field of Epigenetic Histone Modification Through Mass Spectrometry–Based Approaches by Lu, Congcong, Coradin, Mariel, Porter, Elizabeth G., Garcia, Benjamin A.

“…Histone post-translational modifications (PTMs) are one of the main mechanisms of epigenetic regulation. Dysregulation of histone PTMs leads to many human…”
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Middle-down proteomics: a still unexploited resource for chromatin biology by Sidoli, Simone, Garcia, Benjamin A

“…Analysis of histone post-translational modifications (PTMs) by mass spectrometry (MS) has become a fundamental tool for the characterization of chromatin…”
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Capturing the Onset of PRC2-Mediated Repressive Domain Formation by Oksuz, Ozgur, Narendra, Varun, Lee, Chul-Hwan, Descostes, Nicolas, LeRoy, Gary, Raviram, Ramya, Blumenberg, Lili, Karch, Kelly, Rocha, Pedro P., Garcia, Benjamin A., Skok, Jane A., Reinberg, Danny

“…Polycomb repressive complex 2 (PRC2) maintains gene silencing by catalyzing methylation of histone H3 at lysine 27 (H3K27me2/3) within chromatin. By designing…”
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Plant Host-Associated Mechanisms for Microbial Selection by Jones, Piet, Garcia, Benjamin J, Furches, Anna, Tuskan, Gerald A, Jacobson, Daniel

“…Plants serve as host to numerous microorganisms. The members of these microbial communities interact among each other and with the plant, and there is…”
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