Search Results - "García Medina, Jose J"
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Strategies to Reduce Oxidative Stress in Glaucoma Patients
Published in Current neuropharmacology (01-01-2018)“…Background: Primary open-angle glaucoma (POAG) is a multifactorial pathology involving a variety of pathogenic mechanisms, including oxidative/nitrosative…”
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Biochemical-molecular-genetic biomarkers in the tear film, aqueous humor, and blood of primary open-angle glaucoma patients
Published in Frontiers in medicine (26-05-2023)“…Glaucoma is a chronic neurodegenerative disease, which is the leading cause of irreversible blindness worldwide. As a response to high intraocular pressure,…”
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Signature of Circulating Biomarkers in Recurrent Non-Infectious Anterior Uveitis. Immunomodulatory Effects of DHA-Triglyceride. A Pilot Study
Published in Diagnostics (Basel) (19-04-2021)“…The purpose of this study was to identify circulating biomarkers of recurrent non-infectious anterior uveitis (NIAU), and to address the anti-inflammatory…”
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Oxidative stress and mitochondrial failure in the pathogenesis of glaucoma neurodegeneration
Published in Progress in brain research (2015)“…This review focuses on oxidative stress and mitochondrial failure for understanding mechanisms of optic nerve damage in primary open-angle glaucoma. The…”
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Evaluation of presumptive biomarkers of oxidative stress, immune response and apoptosis in primary open-angle glaucoma
Published in Current opinion in pharmacology (01-02-2013)“…Highlights ► Oxidative stress, immune response and apoptosis in POAG initiation and progression. ► Putative glaucoma biomarkers are MDA, TAS, 8-OH-dG,…”
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Searching for the Antioxidant, Anti-Inflammatory, and Neuroprotective Potential of Natural Food and Nutritional Supplements for Ocular Health in the Mediterranean Population
Published in Foods (28-05-2021)“…Adherence to a healthy diet offers a valuable intervention to compete against the increasing cases of ocular diseases worldwide, such as dry eye disorders,…”
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Clinical and Molecular-Genetic Insights into the Role of Oxidative Stress in Diabetic Retinopathy: Antioxidant Strategies and Future Avenues
Published in Antioxidants (01-11-2020)“…Reactive oxygen species (ROS) overproduction and ROS-signaling pathways activation attack the eyes. We evaluated the oxidative stress (OS) and the effects of a…”
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Eclectic Ocular Comorbidities and Systemic Diseases with Eye Involvement: A Review
Published in BioMed research international (01-01-2016)“…Coexistence of several ocular diseases is more frequent than suspected. In spite of the refractive errors, one or more of the following can be detected…”
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Enhanced Oxidative Stress and Other Potential Biomarkers for Retinopathy in Type 2 Diabetics: Beneficial Effects of the Nutraceutic Supplements
Published in BioMed research international (01-01-2015)“…We have studied the global risk of retinopathy in a Mediterranean population of type 2 diabetes mellitus (T2DM) patients, according to clinical, biochemical,…”
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Ocular Comorbidities and the Relationship between Eye Diseases and Systemic Disorders
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Do Nutritional Supplements Have a Role in Age Macular Degeneration Prevention?
Published in Journal of Ophthalmology (01-01-2014)“…Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids…”
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A Multi-Locus Genetic Risk Score for Primary Open-Angle Glaucoma (POAG) Variants Is Associated with POAG Risk in a Mediterranean Population: Inverse Correlations with Plasma Vitamin C and E Concentrations
Published in International journal of molecular sciences (01-11-2017)“…Primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide. The genetics of POAG are complex, and population-specific effects have been…”
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Oxidative Stress Mediates Epigenetic Modifications and the Expression of miRNAs and Genes Related to Apoptosis in Diabetic Retinopathy Patients
Published in Journal of clinical medicine (22-12-2023)“…Knowledge on the underlying mechanisms and molecular targets for managing the ocular complications of type 2 diabetes mellitus (T2DM) remains incomplete…”
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Impact of Systemic Comorbidities on Ocular Hypertension and Open-Angle Glaucoma, in a Population from Spain and Portugal
Published in Journal of clinical medicine (25-09-2022)“…Open-angle glaucoma (OAG), the most prevalent clinical type of glaucoma, is still the main cause of irreversible blindness worldwide. OAG is a…”
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Computational Analysis of Clinical and Molecular Markers and New Theranostic Possibilities in Primary Open-Angle Glaucoma
Published in Journal of clinical medicine (21-09-2020)“…Primary open-angle glaucoma (POAG) is a paramount cause of irreversible visual disability worldwide. We focus on identifying clinical and molecular facts that…”
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Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: Results from the VISIONARY Study Population in Spain
Published in Journal of ocular pharmacology and therapeutics (01-04-2022)“…Data are presented from ophthalmology clinics in Spain participating in the VISIONARY study, examining the effectiveness, tolerability, and safety of the…”
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Respiratory comorbidities. Looking ahead to new glaucoma risk factors
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Purpose: Open‐Angle glaucoma (OAG) continues being the first cause of irreversible blindness worldwide. Recent advances in biotechnology did not cover all…”
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Oxidative Stress in Primary Open-angle Glaucoma
Published in Journal of glaucoma (01-06-2008)“…PURPOSETo analyze oxidative stress in primary open-angle glaucoma (POAG). MATERIAL AND METHODSA case-control study including 90 eyes of 90 patients who needed…”
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miRNAs and Genes Involved in the Interplay between Ocular Hypertension and Primary Open-Angle Glaucoma. Oxidative Stress, Inflammation, and Apoptosis Networks
Published in Journal of clinical medicine (21-05-2021)“…Glaucoma has no cure and is a sight-threatening neurodegenerative disease affecting more than 100 million people worldwide, with primary open angle glaucoma…”
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Ocular Motor Palsy After Spinal Puncture
Published in Regional anesthesia and pain medicine (01-01-2017)“…ABSTRACTOcular motor palsy is a rare but alarming complication of subarachnoid puncture. In order to better understand this condition, a literature search was…”
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