Search Results - "García Martín, Héctor"

Opportunities at the Intersection of Synthetic Biology, Machine Learning, and Automation by Carbonell, Pablo, Radivojevic, Tijana, García Martín, Héctor

“…Our inability to predict the behavior of biological systems severely hampers progress in bioengineering and biomedical applications. We cannot predict the…”
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Accurate phylogenetic classification of variable-length DNA fragments by Rigoutsos, Isidore, McHardy, Alice Carolyn, Martín, Héctor García, Tsirigos, Aristotelis, Hugenholtz, Philip

“…Metagenome studies have retrieved vast amounts of sequence data from a variety of environments leading to new discoveries and insights into the uncultured…”
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Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities by Hugenholtz, Philip, Martín, Héctor García, Ivanova, Natalia, Kunin, Victor, Warnecke, Falk, Barry, Kerrie W, McHardy, Alice C, Yeates, Christine, He, Shaomei, Salamov, Asaf A, Szeto, Ernest, Dalin, Eileen, Putnam, Nik H, Shapiro, Harris J, Pangilinan, Jasmyn L, Rigoutsos, Isidore, Kyrpides, Nikos C, Blackall, Linda Louise, McMahon, Katherine D

“…Enhanced biological phosphorus removal (EBPR) is one of the best-studied microbially mediated industrial processes because of its ecological and economic…”
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ClusterCAD: a computational platform for type I modular polyketide synthase design by Eng, Clara H, Backman, Tyler W H, Bailey, Constance B, Magnan, Christophe, García Martín, Héctor, Katz, Leonard, Baldi, Pierre, Keasling, Jay D

“…Abstract ClusterCAD is a web-based toolkit designed to leverage the collinear structure and deterministic logic of type I modular polyketide synthases (PKSs)…”
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Synthetic and systems biology for microbial production of commodity chemicals by Chubukov, Victor, Mukhopadhyay, Aindrila, Petzold, Christopher J, Keasling, Jay D, Martín, Héctor García

“…The combination of synthetic and systems biology is a powerful framework to study fundamental questions in biology and produce chemicals of immediate practical…”
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On the Origin and Robustness of Power-Law Species-Area Relationships in Ecology by Martín, Héctor García, Goldenfeld, Nigel

“…We present an explanation for the widely reported power-law species-area relationship (SAR), which relates the area occupied by a biome to the number of…”
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A Method to Constrain Genome-Scale Models with 13C Labeling Data by Martín, Héctor García, Kumar, Vinay Satish, Weaver, Daniel, Ghosh, Amit, Chubukov, Victor, Mukhopadhyay, Aindrila, Arkin, Adam, Keasling, Jay D

“…Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired…”
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The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism by Birkel, Garrett W, Ghosh, Amit, Kumar, Vinay S, Weaver, Daniel, Ando, David, Backman, Tyler W H, Arkin, Adam P, Keasling, Jay D, Martín, Héctor García

“…Modeling of microbial metabolism is a topic of growing importance in biotechnology. Mathematical modeling helps provide a mechanistic understanding for the…”
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Automated “Cells-To-Peptides” Sample Preparation Workflow for High-Throughput, Quantitative Proteomic Assays of Microbes by Chen, Yan, Guenther, Joel M, Gin, Jennifer W, Chan, Leanne Jade G, Costello, Zak, Ogorzalek, Tadeusz L, Tran, Huu M, Blake-Hedges, Jacquelyn M, Keasling, Jay D, Adams, Paul D, García Martín, Héctor, Hillson, Nathan J, Petzold, Christopher J

“…Mass spectrometry-based quantitative proteomic analysis has proven valuable for clinical and biotechnology-related research and development. Improvements in…”
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Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases by Barajas, Jesus F., McAndrew, Ryan P., Thompson, Mitchell G., Backman, Tyler W. H., Pang, Bo, de Rond, Tristan, Pereira, Jose H., Benites, Veronica T., Martín, Héctor García, Baidoo, Edward E. K., Hillson, Nathan J., Adams, Paul D., Keasling, Jay D.

“…Engineered polyketide synthases (PKSs) are promising synthetic biology platforms for the production of chemicals with diverse applications. The dehydratase…”
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Flux Analysis of Central Metabolic Pathways in Geobacter metallireducens during Reduction of Soluble Fe(III)-Nitrilotriacetic Acid by Tang, Yinjie J, Chakraborty, Romy, Martín, Héctor García, Chu, Jeannie, Hazen, Terry C, Keasling, Jay D

“…We analyzed the carbon fluxes in the central metabolism of Geobacter metallireducens strain GS-15 using ¹³C isotopomer modeling. Acetate labeled in the first…”
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Erratum to: The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism by Birkel, Garrett W, Ghosh, Amit, Kumar, Vinay S, Weaver, Daniel, Ando, David, Backman, Tyler W H, Arkin, Adam P, Keasling, Jay D, Martín, Héctor García

“…Following publication of this article [1], it has come to our attention that an incomplete version of Fig. 7 was included in this article. The complete figure…”
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Study of stationary phase metabolism via isotopomer analysis of amino acids from an isolated protein by Shaikh, Afshan S., Tang, Yinjie J., Mukhopadhyay, Aindrila, Martín, Héctor García, Gin, Jennifer, Benke, Peter I., Keasling, Jay D.

“…Microbial production of many commercially important secondary metabolites occurs during stationary phase, and methods to measure metabolic flux during this…”
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Common principles and best practices for engineering microbiomes by Lawson, Christopher E., Harcombe, William R., Hatzenpichler, Roland, Lindemann, Stephen R., Löffler, Frank E., O’Malley, Michelle A., García Martín, Héctor, Pfleger, Brian F., Raskin, Lutgarde, Venturelli, Ophelia S., Weissbrodt, David G., Noguera, Daniel R., McMahon, Katherine D.

“…Despite broad scientific interest in harnessing the power of Earth’s microbiomes, knowledge gaps hinder their efficient use for addressing urgent societal and…”
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Flux-Enabled Exploration of the Role of Sip1 in Galactose Yeast Metabolism by Shymansky, Christopher M, Wang, George, Baidoo, Edward E K, Gin, Jennifer, Apel, Amanda Reider, Mukhopadhyay, Aindrila, García Martín, Héctor, Keasling, Jay D

“…C metabolic flux analysis ( C MFA) is an important systems biology technique that has been used to investigate microbial metabolism for decades. The…”
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Microbial Synthesis of Pinene by Sarria, Stephen, Wong, Betty, Martín, Hector García, Keasling, Jay D, Peralta-Yahya, Pamela

“…The volumetric heating values of today’s biofuels are too low to power energy-intensive aircraft, rockets, and missiles. Recently, pinene dimers were shown to…”
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A method to constrain genome-scale models with [sup.13]C labeling data by Martin, Hector Garcia, Kumar, Vinay Satish, Weaver, Daniel, Ghosh, Amit, Chubukov, Victor, Mukhopadhyay, Aindrila, Arkin, Adam, Keasling, Jay D

“…Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired…”
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A peptide-based method for [sup.13]C metabolic flux analysis in microbial communities by Ghosh, Amit, Nilmeier, Jerome, Weaver, Daniel, Adams, Paul D, Keasling, Jay D, Mukhopadhyay, Aindrila, Petzold, Christopher J, Martin, Hector Garcia

“…The study of intracellular metabolic fluxes and inter-species metabolite exchange for microbial communities is of crucial importance to understand and predict…”
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A High-Quality Genome-Scale Model for Rhodococcus opacus Metabolism by Roell, Garrett W., Schenk, Christina, Anthony, Winston E., Carr, Rhiannon R., Ponukumati, Aditya, Kim, Joonhoon, Akhmatskaya, Elena, Foston, Marcus, Dantas, Gautam, Moon, Tae Seok, Tang, Yinjie J., García Martín, Hector

“…Rhodococcus opacus is a bacterium that has a high tolerance to aromatic compounds and can produce significant amounts of triacylglycerol (TAG). Here, we…”
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A Method to Constrain Genome-Scale Models with 13 C Labeling Data: e1004363 by Martín, Héctor García, Kumar, Vinay Satish, Weaver, Daniel, Ghosh, Amit, Chubukov, Victor, Mukhopadhyay, Aindrila, Arkin, Adam, Keasling, Jay D

“…Current limitations in quantitatively predicting biological behavior hinder our efforts to engineer biological systems to produce biofuels and other desired…”
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