Search Results - "García Llorca, Andrea"
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Mouse microphthalmia‐associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Purpose Mice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and…”
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Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal Arteries
Published in International journal of molecular sciences (02-05-2023)“…It has been demonstrated previously that a variety of carbonic anhydrase inhibitors (CAIs) can induce vasodilation in pre-contracted retinal arteriolar…”
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Dopamine is involved in regulating vascular tone in retinal arterioles
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Purpose: There is clinical evidence suggesting that the neurotransmitter dopamine may play a role in regulating retinal vascular function. Patients with…”
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Sex-Related Effects of Gut Microbiota in Metabolic Syndrome-Related Diabetic Retinopathy
Published in Microorganisms (Basel) (01-02-2023)“…The metabolic syndrome (MetS) is a complex disease of metabolic abnormalities, including obesity, insulin resistance, hypertension and dyslipidaemia, and it is…”
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Different rate of retinal degenerations in mice with two distinct mutations in the Mitf gene
Published in Acta ophthalmologica (Oxford, England) (01-12-2019)“…Purpose The microphthalmia‐associated transcription factor (Mitf) gene is crucial for development of the retinal pigment epithelium (RPE) and photoreceptors…”
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A conditional Mitf mouse model of geographic atrophy (GA)
Published in Acta ophthalmologica (Oxford, England) (01-12-2019)“…Purpose Mice carrying different mutations in the microphthalmia‐associated transcription factor (Mitf) gene, affect the normal the retinal pigment epithelium…”
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Carbonic anhydrase, its inhibitors and vascular function
Published in Frontiers in molecular biosciences (2024)“…It has been known for some time that Carbonic Anhydrase (CA, EC 4.2.1.1) plays a complex role in vascular function, and in the regulation of vascular tone…”
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Measuring Retinal Vessel Diameter from Mouse Fluorescent Angiography Images
Published in Journal of visualized experiments (19-05-2023)“…It is important to study the development of retinal vasculature in retinopathies in which abnormal vessel growth can ultimately lead to vision loss. Mutations…”
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The Microphthalmia-Associated Transcription Factor (MITF) and Its Role in the Structure and Function of the Eye
Published in Genes (27-09-2024)“…The microphthalmia-associated transcription factor ( ) has been found to play an important role in eye development, structure, and function. The gene is…”
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Mitfmi/+ as a new mouse model of cone dystrophy
Published in Acta ophthalmologica (Oxford, England) (01-12-2022)“…Purpose: Mutations in the Mitf gene can lead to hypopigmentation, microphthalmia, retinal degeneration, deafness and blindness1. We have previously shown that…”
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Vasodilation of Pre-contracted Porcine Retinal Arteries by Carbonic Anhydrase Inhibitors with Enhanced Lipophilicity
Published in Current eye research (02-12-2022)“…In this study, we investigated the vasodilation properties on pre-contracted retinal arteries of a restricted series of carbonic anhydrase inhibitors (CAIs) of…”
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The microphthalmia-associated transcription factor (Mitf) gene and its role in regulating eye function
Published in Scientific reports (28-10-2019)“…Mutations in the microphthalmia-associated transcription factor ( Mitf ) gene can cause retinal pigment epithelium (RPE) and retinal dysfunction and…”
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Progressive Cone-Rod Dystrophy and RPE Dysfunction in Mitfmi/+ Mice
Published in Genes (17-07-2023)“…Mutations in the mouse microphthalmia-associated transcription factor (Mitf) gene affect retinal pigment epithelium (RPE) differentiation and development and…”
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Progressive Cone-Rod Dystrophy and RPE Dysfunction in IMitfmi/+/I Mice
Published in Genes (01-07-2023)“…Mutations in the mouse microphthalmia-associated transcription factor (Mitf) gene affect retinal pigment epithelium (RPE) differentiation and development and…”
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Progressive Cone-Rod Dystrophy and RPE Dysfunction in Mitf mi/+ Mice
Published in Genes (17-07-2023)“…Mutations in the mouse microphthalmia-associated transcription factor ( ) gene affect retinal pigment epithelium (RPE) differentiation and development and can…”
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