Search Results - "García Ibarbia"
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The poor accuracy of D-dimer for the diagnosis of prosthetic joint infection but its potential usefulness in early postoperative infections following revision arthroplasty for aseptic loosening
Published in BMC infectious diseases (27-01-2022)“…D-dimer was introduced in 2018 as an alternative biomarker for C-reactive protein (CRP) in the diagnostic of prosthetic joint infection (PJI) criteria of the…”
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National digestive disease specialists survey on cardiovascular risk management in non‐alcoholic fatty liver disease in spanish hospitals
Published in Liver international (01-06-2021)“…Background & Aims Cardiovascular disease (CVD) is the main cause of mortality among non‐alcoholic fatty liver disease (NAFLD) patients. The aim was to explore…”
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3
Osterix and RUNX2 are Transcriptional Regulators of Sclerostin in Human Bone
Published in Calcified tissue international (01-09-2016)“…Sclerostin, encoded by the SOST gene, works as an inhibitor of the Wnt pathway and therefore is an important regulator of bone homeostasis. Due to its potent…”
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Methylprednisolone in adults hospitalized with COVID-19 pneumonia: An open-label randomized trial (GLUCOCOVID)
Published in Wiener Klinische Wochenschrift (01-04-2021)“…Summary Purpose To determine whether a 6-day course of methylprednisolone (MP) improves outcome in patients with severe SARS-CoV‑2 (Corona Virus Disease 2019…”
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Genome‐wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-01-2013)“…Objective To determine genome‐wide methylation profiles of bone from patients with hip osteoarthritis (OA) and those with osteoporotic (OP) hip fractures…”
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High Frequencies of Genetic Variants in Patients with Atypical Femoral Fractures
Published in International journal of molecular sciences (01-02-2024)“…This study explores the genetic factors associated with atypical femoral fractures (AFF), rare fractures associated with prolonged anti-resorptive therapy. AFF…”
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Contribution of genetic and epigenetic mechanisms to Wnt pathway activity in prevalent skeletal disorders
Published in Gene (15-12-2013)“…We reported previously that the expression of Wnt-related genes is lower in osteoporotic hip fractures than in osteoarthritis. We aimed to confirm those…”
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Combining familial hypercholesterolemia and statin genetic studies as a strategy for the implementation of pharmacogenomics. A multidisciplinary approach
Published in The pharmacogenomics journal (01-05-2022)“…The diagnostic process of familial hypercholesterolemia frequently involves the use of genetic studies. Patients are treated with lipid-lowering drugs,…”
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Epidemiological and genetic features of anti-3‑hydroxy-3-methylglutaryl-CoA reductase necrotizing myopathy: Single-center experience and literature review
Published in European journal of internal medicine (01-07-2022)“…•In northern Spain, anti-HMGCR IMNM usually affects people over 50 years with exposure to statins.•We confirm that HLA-DRB1×11 is associated with an increased…”
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Non-synonymous WNT16 polymorphisms alleles are associated with different osteoarthritis phenotypes
Published in Rheumatology international (01-10-2017)“…Hereditary factors have a strong influence on osteoarthritis (OA). The Wnt pathway is involved in bone and cartilage homeostasis. Hence, we hypothesized that…”
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Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication
Published in European journal of endocrinology (01-01-2011)“…ObjectiveGenes explaining the susceptibility to osteoporosis have not been fully elucidated. Our objective was to explore the association of polymorphisms…”
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Common variations in estrogen-related genes are associated with severe large-joint osteoarthritis: a multicenter genetic and functional study
Published in Osteoarthritis and cartilage (01-07-2010)“…Summary Objective Several lines of evidence suggest that estrogens influence the development of osteoarthritis (OA). The aim of this study was to explore the…”
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13
Osteocyte Deficiency in Hip Fractures
Published in Calcified tissue international (01-10-2011)“…Osteocytes play a central role in the regulation of bone remodeling. The aim of this study was to explore osteocyte function, and particularly the expression…”
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Wnt-related genes and large-joint osteoarthritis: association study and replication
Published in Rheumatology international (01-11-2013)“…Osteoarthritis (OA) has a strong genetic component, and experimental evidence suggests the involvement of the Wnt pathway in its pathogenesis. Hence, we…”
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Genetic Polymorphisms of the Wnt Receptor LRP5 are Differentially Associated with Trochanteric and Cervical Hip Fractures
Published in Calcified tissue international (01-02-2012)“…Epidemiological studies suggest that cervical and trochanteric hip fractures have different pathogenesis. We tested the hypothesis that genetic factors have…”
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Método sensible para monitorizar la migración de las células madre mesenquimales de la médula ósea en modelos murinos
Published in Revista de osteoporosis y metabolismo mineral (01-06-2020)“…Resumen Objetivo: Las células madre mesenquimales (MSCs) son atractivas en la terapia regenerativa de patologías humanas. En los modelos murinos, en los que se…”
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Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures
Published in Osteoporosis international (01-09-2013)“…Summary Two missense polymorphisms of WNT16 were associated with hip bone mineral density (BMD), the buckling ratio of the femoral neck, calcaneal ultrasound…”
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Influencia del oxígeno a alta concentración en cámara hiperbárica sobre el metabolismo óseo
Published in Revista de osteoporosis y metabolismo mineral (01-03-2020)“…Resumen Objetivos: Conocer las acciones del oxígeno a alta concentración en cámara hiperbárica (CH) sobre la expresión de genes relacionados con el metabolismo…”
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Impacto funcional de polimorfismos del gen de la esclerostina sobre la metilación de ADN y la expresión génica
Published in Revista de osteoporosis y metabolismo mineral (01-12-2019)“…Resumen Introducción Varios estudios de barrido genómico (GWAS) y otros focalizados en el gen de la esclerostina (SOST) han encontrado que algunos…”
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Etanercept-induced hypertriglyceridemia during the treatment of recurrent aphthous stomatitis
Published in Indian journal of dermatology, venereology, and leprology (01-05-2013)“…Different conditions that may present with RAS such as Behηet's disease, gastrointestinal disorders, nutritional deficiencies, human immunodeficiency virus,…”
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