Search Results - "García Del Caño, Gontzal"
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Intermittent ethanol exposure during adolescence impairs cannabinoid type 1 receptor-dependent long-term depression and recognition memory in adult mice
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2020)“…Binge drinking is a significant problem in adolescent populations, and because of the reciprocal interactions between ethanol (EtOH) consumption and the…”
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Effects of Platelet-Rich Plasma on Cellular Populations of the Central Nervous System: The Influence of Donor Age
Published in International journal of molecular sciences (09-02-2021)“…Platelet-rich plasma (PRP) is a biologic therapy that promotes healing responses across multiple medical fields, including the central nervous system (CNS)…”
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3
Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors
Published in Pain (Amsterdam) (01-07-2012)“…Plasticity of serotonergic neurotransmission mediated by 5-HT2A and 5-HT2B receptors impairs spinal mu-opioid of receptor efficacy during neuropathic pain,…”
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Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization
Published in International journal of molecular sciences (05-03-2022)“…Platelet-Rich Plasma (PRP) is enriched in molecular messengers with restorative effects on altered tissue environments. Upon activation, platelets release a…”
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Tuning the properties of peptide imprinted nanoparticles for protein immunoprecipitation using magnetic streptavidin beads
Published in Mikrochimica acta (1966) (01-11-2024)“…Maximizing the binding properties of thermoresponsive molecularly imprinted nanoparticles (MIN) was aimed to explore their feasibility as antibody substitutes…”
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Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex
Published in Molecules (Basel, Switzerland) (16-11-2021)“…Numerous studies have investigated the roles of the type 1 cannabinoid receptor (CB1) in glutamatergic and GABAergic neurons. Here, we used the…”
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Dopamine D1-like Receptors Regulate Constitutive, μ-Opioid Receptor-Mediated Repression of Use-Dependent Synaptic Plasticity in Dorsal Horn Neurons: More Harm than Good?
Published in The Journal of neuroscience (18-05-2016)“…The current study reports on a synaptic mechanism through which D1-like receptors (D1LRs) modulate spinal nociception and plasticity by regulating activation…”
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Fit-for-purpose based testing and validation of antibodies to amino- and carboxy-terminal domains of cannabinoid receptor 1
Published in Histochemistry and cell biology (01-11-2021)“…Specific and selective anti-CB 1 antibodies are among the most powerful research tools to unravel the complex biological processes mediated by the CB 1…”
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Time-dependent cross talk between spinal serotonin 5-HT2A receptor and mGluR1 subserves spinal hyperexcitability and neuropathic pain after nerve injury
Published in The Journal of neuroscience (26-09-2012)“…Emerging evidence implicates serotonergic descending facilitatory pathways from the brainstem to the spinal cord in the maintenance of pathologic pain…”
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PLCβ1 by-passes early growth response -1 to induce the differentiation of neuronal cells
Published in Cell death discovery (24-05-2024)“…The Gα q /phospholipase C-β (PLCβ) signaling system mediates calcium responses to a variety of hormones and neurotransmitters. Recent studies suggest that…”
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New Insights into Gene Delivery to Human Neuronal Precursor NT2 Cells: A Comparative Study between Lipoplexes, Nioplexes, and Polyplexes
Published in Molecular pharmaceutics (02-11-2015)“…The transfection of human NTera2/D1 teratocarcinoma-derived cell line (or NT2 cells) represents a promising strategy for the delivery of exogenous proteins or…”
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Organization and origin of the connection from the inferior to the superior colliculi in the rat
Published in Journal of comparative neurology (1911) (10-12-2006)“…The inferior colliculus (IC) is the main ascending auditory relay station prior to the superior colliculus (SC). The morphology and origin of the connection…”
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Schwannomin-Interacting Protein-1 Isoform IQCJ-SCHIP-1 Is a Late Component of Nodes of Ranvier and Axon Initial Segments
Published in The Journal of neuroscience (11-06-2008)“…Axon initial segments (AISs) and nodes of Ranvier (NRs) are essential regions for saltatory conduction of the action potential along the axon. These two…”
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CK2‐regulated schwannomin‐interacting protein IQCJ‐SCHIP‐1 association with AnkG contributes to the maintenance of the axon initial segment
Published in Journal of neurochemistry (01-08-2015)“…The axon initial segment (AIS) plays a central role in electrogenesis and in the maintenance of neuronal polarity. Its molecular organization is dependent on…”
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Expression pattern of calcitonin gene-related peptide in the superior colliculus during postnatal development: Demonstration of its intrinsic nature and possible roles
Published in Journal of comparative neurology (1911) (10-02-2006)“…Calcitonin gene‐related peptide (CGRP) is a widespread neuropeptide with multiple central and peripheral targets. In an analysis on the expression of this…”
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Endocannabinoid 2-Arachidonoylglycerol Synthesis and Metabolism at Neuronal Nuclear Matrix Fractions Derived from Adult Rat Brain Cortex
Published in International journal of molecular sciences (01-02-2023)“…In this report, we describe the kinetics characteristics of the diacylglycerol lipase-α (DGLα) located at the nuclear matrix of nuclei derived from adult…”
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Plastic reaction of the rat visual corticocollicular connection after contralateral retinal deafferentiation at the neonatal or adult stage: Axonal growth versus reactive synaptogenesis
Published in Journal of comparative neurology (1911) (29-04-2002)“…The effects of neonatal or adult enucleation on the final adult pattern of the rat visual corticocollicular (C‐Co) connection were studied using the…”
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Solid-phase synthesis of imprinted nanoparticles as artificial antibodies against the C-terminus of the cannabinoid CB1 receptor: exploring a viable alternative for bioanalysis
Published in Mikrochimica acta (1966) (01-11-2021)“…The production of artificial anti-CB1 antibodies in nanoparticle format is described using the solid-phase imprinting approach. Instead of whole protein…”
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Abstract 1948: Phospholipase Cβ1 Induces Differentiation of Neuronal Cell Lines
Published in The Journal of biological chemistry (2023)Get full text
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Design and validation of recombinant protein standards for quantitative Western blot analysis of cannabinoid CB1 receptor density in cell membranes: an alternative to radioligand binding methods
Published in Microbial cell factories (15-09-2022)“…Abstract Background Replacement of radioligand binding assays with antibody-antigen interaction-based approaches for quantitative analysis of G protein-coupled…”
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