Search Results - "García Cerro, Susana"

Inflammatory dysregulation of monocytes in pediatric patients with obsessive-compulsive disorder by Rodríguez, Natalia, Morer, Astrid, González-Navarro, E Azucena, Serra-Pages, Carles, Boloc, Daniel, Torres, Teresa, García-Cerro, Susana, Mas, Sergi, Gassó, Patricia, Lázaro, Luisa

“…Although the exact etiology of obsessive-compulsive disorder (OCD) is unknown, there is growing evidence of a role for immune dysregulation in the…”
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Identifying key transcription factors for pharmacogenetic studies of antipsychotics induced extrapyramidal symptoms by Boloc, Daniel, Rodríguez, Natalia, Torres, Teresa, García-Cerro, Susana, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manuel J., Bernardo, Miquel, Gassó, Patricia, Lafuente, Amalia, Mas, Sergi, Arnaiz, Joan Albert

“…Introduction We explore the transcription factors involved in the molecular mechanism of antipsychotic (AP)-induced acute extrapyramidalsymptoms (EPS) in order…”
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Normalizing the gene dosage of Dyrk1A in a mouse model of Down syndrome rescues several Alzheimer's disease phenotypes by García-Cerro, Susana, Rueda, Noemí, Vidal, Verónica, Lantigua, Sara, Martínez-Cué, Carmen

“…Abstract The intellectual disability that characterizes Down syndrome (DS) is primarily caused by prenatal changes in central nervous system growth and…”
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Exploratory Analysis of MicroRNA Alterations in a Neurodevelopmental Mouse Model for Autism Spectrum Disorder and Schizophrenia by García-Cerro, Susana, Gómez-Garrido, Ana, Garcia, Gonçalo, Crespo-Facorro, Benedicto, Brites, Dora

“…MicroRNAs (miRNAs) play a crucial role in the regulation of gene expression levels and have been implicated in the pathogenesis of autism spectrum disorder…”
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Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome by García-Cerro, Susana, Martínez, Paula, Vidal, Verónica, Corrales, Andrea, Flórez, Jesús, Vidal, Rebeca, Rueda, Noemí, Arbonés, María L, Martínez-Cué, Carmen

“…Down syndrome (DS) phenotypes result from the overexpression of several dosage-sensitive genes. The DYRK1A (dual-specificity tyrosine-(Y)-phosphorylation…”
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Efficacy of clozapine versus standard treatment in adult individuals with intellectual disability and treatment-resistant psychosis (CLOZAID): study protocol of a multicenter randomized clinical trial by Alemany-Navarro, María, Sánchez-Barbero, Bianca, Reguera-Pozuelo, Pablo, Altea-Manzano, Laura, Gómez-Garrido, Ana, Rocha-González, Idalino, Garrido-Torres, Nathalia, Ruiz-Veguilla, Miguel, García-Cerro, Susana, Rosso-Fernández, Clara M, Villagrán-Moreno, José María, Sarramea, Fernando, Cervilla-Ballesteros, Jorge, Martínez-Leal, Rafael, Mayoral-Cleries, Fermín, Crespo-Facorro, Benedicto

“…Intellectual disability (ID) affects approximately 1% of the worldwide population and individuals with ID have a higher comorbidity with mental illness, and…”
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Cerebellar alterations in a model of Down syndrome: The role of the Dyrk1A gene by García-Cerro, Susana, Vidal, Verónica, Lantigua, Sara, Berciano, Maria Teresa, Lafarga, Miguel, Ramos-Cabrer, Pedro, Padro, Daniel, Rueda, Noemí, Martínez-Cué, Carmen

“…Down syndrome (DS) is characterized by a marked reduction in the size of the brain and cerebellum. These changes play an important role in the motor…”
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Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer's Disease by Vidal, Verónica, Puente, Alba, García-Cerro, Susana, García Unzueta, María Teresa, Rueda, Noemí, Riancho, Javier, Martínez-Cué, Carmen

“…All individuals with Down syndrome (DS) eventually develop Alzheimer's disease (AD) neuropathology, including neurodegeneration, increases in -amyloid (Aβ)…”
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Author Correction: Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics by Boloc, Daniel, Gortat, Anna, Cheng-Zhang, Jia Qi, García-Cerro, Susana, Rodríguez, Natalia, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manolo J., Gassó, Patricia, Lafuente, Amalia, Bernardo, Miquel, Mas, Sergi

“…One of the funding sources (FEDER-Unión Europea) was not previously acknowledged in this Article. This study was supported by the Spanish Ministry of Health,…”
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miRNAs as biomarkers of autism spectrum disorder: a systematic review and meta-analysis by Garrido-Torres, Nathalia, Guzmán-Torres, Karem, García-Cerro, Susana, Pinilla Bermúdez, Gladys, Cruz-Baquero, Claudia, Ochoa, Hansel, García-González, Diego, Canal-Rivero, Manuel, Crespo-Facorro, Benedicto, Ruiz-Veguilla, Miguel

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex clinical manifestations that arise between 18 and 36 months of age. Social…”
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Prenatal Administration of Oleic Acid or Linolenic Acid Reduces Neuromorphological and Cognitive Alterations in Ts65dn Down Syndrome Mice by García-Cerro, Susana, Rueda, Noemí, Vidal, Verónica, Puente, Alba, Campa, Víctor, Lantigua, Sara, Narcís, Oriol, Velasco, Ana, Bartesaghi, Renata, Martínez-Cué, Carmen

“…The cognitive impairments that characterize Down syndrome (DS) have been attributed to brain hypocellularity due to neurogenesis impairment during fetal…”
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Prenatal, but not Postnatal, Curcumin Administration Rescues Neuromorphological and Cognitive Alterations in Ts65Dn Down Syndrome Mice by Rueda, Noemí, Vidal, Verónica, García-Cerro, Susana, Puente, Alba, Campa, Víctor, Lantigua, Sara, Narcís, Oriol, Bartesaghi, Renata, Martínez-Cué, Carmen

“…The cognitive dysfunction in Down syndrome (DS) is partially caused by deficient neurogenesis during fetal stages. Curcumin enhances neurogenesis and learning…”
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The positive allosteric modulator of the mGlu2 receptor JNJ-46356479 partially improves neuropathological deficits and schizophrenia-like behaviors in a postnatal ketamine mice model by Martínez-Pinteño, Albert, García-Cerro, Susana, Mas, Sergi, Torres, Teresa, Boloc, Daniel, Rodríguez, Natalia, Lafuente, Amalia, Gassó, Patricia, Arnaiz, Joan Albert, Parellada, Eduard

“…Current antipsychotics have limited efficacy in controlling cognitive and negative symptoms of schizophrenia (SZ). Glutamatergic dysregulation has been…”
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Early postnatal oleic acid administration enhances synaptic development and cognitive abilities in the Ts65Dn mouse model of Down syndrome by Vidal, Verónica, García-Cerro, Susana, Rueda, Noemí, Puente, Alba, Bartesaghi, Renata, Martínez-Cué, Carmen

“…The brains of individuals with Down syndrome (DS) present defects in neurogenesis and synaptogenesis during prenatal and early postnatal stages that are…”
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Exploring genetic testing requests, genetic alterations and clinical associations in a cohort of children with autism spectrum disorder by Garrido-Torres, Nathalia, Marqués Rodríguez, Renata, Alemany-Navarro, María, Sánchez-García, Javier, García-Cerro, Susana, Ayuso, María Irene, González-Meneses, Antonio, Martinez-Mir, Amalia, Ruiz-Veguilla, Miguel, Crespo-Facorro, Benedicto

“…Several studies show great heterogeneity in the type of genetic test requested and in the clinicopathological characteristics of patients with ASD. The…”
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Microarray gene-expression study in fibroblast and lymphoblastoid cell lines from antipsychotic-naïve first-episode schizophrenia patients by Gassó, Patricia, Mas, Sergi, Rodríguez, Natalia, Boloc, Daniel, García-Cerro, Susana, Bernardo, Miquel, Lafuente, Amalia, Parellada, Eduard

“…Schizophrenia (SZ) is a chronic psychiatric disorder whose onset of symptoms occurs in late adolescence and early adulthood. The etiology is complex and…”
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Anti-IL17 treatment ameliorates Down syndrome phenotypes in mice by Rueda, Noemí, Vidal, Verónica, García-Cerro, Susana, Narcís, Josep Oriol, Llorens-Martín, María, Corrales, Andrea, Lantigua, Sara, Iglesias, Marcos, Merino, Jesús, Merino, Ramón, Martínez-Cué, Carmen

“…•Ts65Dn mice show an altered neuroinflammatory milieu in the hippocampus.•Anti-IL17 treatment improves the cognitive abilities of TS mice.•Anti-IL17 reduces…”
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Chronic Melatonin Administration Reduced Oxidative Damage and Cellular Senescence in the Hippocampus of a Mouse Model of Down Syndrome by Parisotto, Eduardo B., Vidal, Verónica, García-Cerro, Susana, Lantigua, Sara, Wilhelm Filho, Danilo, Sanchez-Barceló, Emilio J., Martínez-Cué, Carmen, Rueda, Noemí

“…Previous studies have demonstrated that melatonin administration improves spatial learning and memory and hippocampal long-term potentiation in the adult…”
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Pre- and post-natal melatonin administration partially regulates brain oxidative stress but does not improve cognitive or histological alterations in the Ts65Dn mouse model of Down syndrome by Corrales, Andrea, Parisotto, Eduardo B., Vidal, Verónica, García-Cerro, Susana, Lantigua, Sara, Diego, Marian, Wilhem Filho, Danilo, Sanchez-Barceló, Emilio J., Martínez-Cué, Carmen, Rueda, Noemí

“…•Neuroprotective effects of melatonin at early stages were evaluated in the TS mice.•Melatonin administered at early stages did not improve cognition in the TS…”
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Improving pharmacogenetic prediction of extrapyramidal symptoms induced by antipsychotics by Boloc, Daniel, Gortat, Anna, Cheng-Zhang, Jia Qi, García-Cerro, Susana, Rodríguez, Natalia, Parellada, Mara, Saiz-Ruiz, Jeronimo, Cuesta, Manolo J., Gassó, Patricia, Lafuente, Amalia, Bernardo, Miquel, Mas, Sergi

“…In previous work we developed a pharmacogenetic predictor of antipsychotic (AP) induced extrapyramidal symptoms (EPS) based on four genes involved in mTOR…”
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