Search Results - "García Canadilla, Patricia"
-
1
Myoarchitectural disarray of hypertrophic cardiomyopathy begins pre‐birth
Published in Journal of anatomy (01-11-2019)“…Myoarchitectural disarray – the multiscalar disorganisation of myocytes, is a recognised histopathological hallmark of adult human hypertrophic cardiomyopathy…”
Get full text
Journal Article -
2
-
3
Whole heart detailed and quantitative anatomy, myofibre structure and vasculature from X-ray phase-contrast synchrotron radiation-based micro computed tomography
Published in European heart journal cardiovascular imaging (01-07-2017)“…While individual cardiac myocytes only have a limited ability to shorten, the heart efficiently pumps a large volume-fraction thanks to a cell organization in…”
Get full text
Journal Article -
4
Structural coronary artery remodelling in the rabbit fetus as a result of intrauterine growth restriction
Published in PloS one (21-06-2019)“…Intrauterine growth restriction (IUGR) is a fetal condition that affects up to 10% of all pregnancies and is associated with cardiovascular structural and…”
Get full text
Journal Article -
5
Permanent cardiac sarcomere changes in a rabbit model of intrauterine growth restriction
Published in PloS one (17-11-2014)“…Intrauterine growth restriction (IUGR) induces fetal cardiac remodelling and dysfunction, which persists postnatally and may explain the link between low birth…”
Get full text
Journal Article -
6
A computational model of the fetal circulation to quantify blood redistribution in intrauterine growth restriction
Published in PLoS computational biology (01-06-2014)“…Intrauterine growth restriction (IUGR) due to placental insufficiency is associated with blood flow redistribution in order to maintain delivery of oxygenated…”
Get full text
Journal Article -
7
Acute myocarditis with transient myocardial thickening in two oncologic patients treated with anti‐GD2 immunotherapy
Published in ESC Heart Failure (01-06-2023)“…Immunotherapy has considerably improved clinical outcomes in different types of cancers but has also been associated with the development of myocarditis,…”
Get full text
Journal Article -
8
Remodeling of the cardiovascular circulation in fetuses of mothers with diabetes: A fetal computational model analysis
Published in Placenta (Eastbourne) (01-03-2018)“…Myocardial structural and functional abnormalities are known to occur in fetuses of mothers with diabetes mellitus (FMDM). The main aim of this investigation…”
Get full text
Journal Article -
9
Machine Learning in Fetal Cardiology: What to Expect
Published in Fetal diagnosis and therapy (01-05-2020)“…In fetal cardiology, imaging (especially echocardiography) has demonstrated to help in the diagnosis and monitoring of fetuses with a compromised…”
Get more information
Journal Article -
10
Pulmonary vascular reactivity in growth restricted fetuses using computational modelling and machine learning analysis of fetal Doppler waveforms
Published in Scientific reports (11-03-2024)“…The aim of this study was to investigate the pulmonary vasculature in baseline conditions and after maternal hyperoxygenation in growth restricted fetuses…”
Get full text
Journal Article -
11
Complex Congenital Heart Disease Associated With Disordered Myocardial Architecture in a Midtrimester Human Fetus
Published in Circulation. Cardiovascular imaging (01-10-2018)“…In the era of increasingly successful corrective interventions in patients with congenital heart disease (CHD), global and regional myocardial remodeling are…”
Get full text
Journal Article -
12
Comprehensive assessment of myocardial remodeling in ischemic heart disease by synchrotron propagation based X-ray phase contrast imaging
Published in Scientific reports (07-07-2021)“…Cardiovascular research is in an ongoing quest for a superior imaging method to integrate gross-anatomical information with microanatomy, combined with…”
Get full text
Journal Article -
13
Cardiac dysfunction is associated with altered sarcomere ultrastructure in intrauterine growth restriction
Published in American journal of obstetrics and gynecology (01-06-2014)“…Objective The purpose of this study was to assess whether abnormal cardiac function in human fetuses with intrauterine growth restriction (IUGR) is associated…”
Get full text
Journal Article -
14
A scalable and transparent data pipeline for AI-enabled health data ecosystems
Published in Frontiers in medicine (30-07-2024)“…Transparency and traceability are essential for establishing trustworthy artificial intelligence (AI). The lack of transparency in the data preparation process…”
Get full text
Journal Article -
15
Detailed quantification of cardiac ventricular myocardial architecture in the embryonic and fetal mouse heart by application of structure tensor analysis to high resolution episcopic microscopic data
Published in Frontiers in cell and developmental biology (16-11-2022)“…The mammalian heart, which is one of the first organs to form and function during embryogenesis, develops from a simple tube into a complex organ able to…”
Get full text
Journal Article -
16
Machine Learning-Based Systems for the Anticipation of Adverse Events After Pediatric Cardiac Surgery
Published in Frontiers in pediatrics (27-06-2022)“…Pediatric congenital heart disease (CHD) patients are at higher risk of postoperative complications and clinical deterioration either due to their underlying…”
Get full text
Journal Article -
17
A tomographic microscopy-compatible Langendorff system for the dynamic structural characterization of the cardiac cycle
Published in Frontiers in cardiovascular medicine (22-12-2022)“…Cardiac architecture has been extensively investigated using a broad spectrum of imaging techniques. Nevertheless, the heart is a dynamic system and the…”
Get full text
Journal Article -
18
A two dimensional electromechanical model of a cardiomyocyte to assess intra-cellular regional mechanical heterogeneities
Published in PloS one (24-08-2017)“…Experimental studies on isolated cardiomyocytes from different animal species and human hearts have demonstrated that there are regional differences in the…”
Get full text
Journal Article -
19
Patient-specific estimates of vascular and placental properties in growth-restricted fetuses based on a model of the fetal circulation
Published in Placenta (Eastbourne) (01-09-2015)“…Abstract Introduction Intrauterine growth restriction (IUGR) due to placental insufficiency is associated with blood-flow redistribution in order to maintain…”
Get full text
Journal Article -
20
MicroCT imaging reveals differential 3D micro-scale remodelling of the murine aorta in ageing and Marfan syndrome
Published in Theranostics (01-01-2018)“…Aortic wall remodelling is a key feature of both ageing and genetic connective tissue diseases, which are associated with vasculopathies such as Marfan…”
Get full text
Journal Article