Search Results - "García‐Villalba, Rocío"

Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status by Tomás‐Barberán, Francisco A., González‐Sarrías, Antonio, García‐Villalba, Rocío, Núñez‐Sánchez, María A., Selma, María V., García‐Conesa, María T., Espín, Juan Carlos

“…Urolithins are dibenzo[b,d]pyran‐6‐one derivatives that are produced by the human gut microbiota from ellagitannins and ellagic acid (EA). These metabolites…”
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Urolithins: a Comprehensive Update on their Metabolism, Bioactivity, and Associated Gut Microbiota by García‐Villalba, Rocío, Giménez‐Bastida, Juan Antonio, Cortés‐Martín, Adrián, Ávila‐Gálvez, María Ángeles, Tomás‐Barberán, Francisco A., Selma, María Victoria, Espín, Juan Carlos, González‐Sarrías, Antonio

“…Urolithins, metabolites produced by the gut microbiota from the polyphenols ellagitannins and ellagic acid, are discovered by the research group in humans…”
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In vitro transformation of chlorogenic acid by human gut microbiota by Tomas‐Barberan, Francisco, García‐Villalba, Rocío, Quartieri, Andrea, Raimondi, Stefano, Amaretti, Alberto, Leonardi, Alan, Rossi, Maddalena

“…SCOPE: Chlorogenic acid (3‐O‐caffeoyl‐quinic acid, C‐QA), the caffeic ester of quinic acid, is one of the most abundant phenolic acids in Western diet. The…”
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Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight‐obese individuals consuming pomegranate: A randomized clinical trial by González‐Sarrías, Antonio, García‐Villalba, Rocío, Romo‐Vaquero, María, Alasalvar, Cesarettin, Örem, Asim, Zafrilla, Pilar, Tomás‐Barberán, Francisco A., Selma, María V., Espín, Juan Carlos

“…Scope The pomegranate lipid‐lowering properties remain controversial, probably due to the interindividual variability in polyphenol (ellagitannins) metabolism…”
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Time Course Production of Urolithins from Ellagic Acid by Human Gut Microbiota by García-Villalba, Rocío, Beltrán, David, Espín, Juan Carlos, Selma, María Victoria, Tomás-Barberán, Francisco A

“…Ellagic acid (EA) is converted to urolithins by gut microbiota. Urolithins have beneficial biological effects in humans, but differences in urolithin…”
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Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status by Tomás-Barberán, Francisco A, García-Villalba, Rocío, González-Sarrías, Antonio, Selma, María V, Espín, Juan C

“…Three phenotypes for urolithin production after ellagitannin and ellagic acid intake are consistently observed in different human intervention trials. Subjects…”
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The Endotoxemia Marker Lipopolysaccharide‐Binding Protein is Reduced in Overweight‐Obese Subjects Consuming Pomegranate Extract by Modulating the Gut Microbiota: A Randomized Clinical Trial by González‐Sarrías, Antonio, Romo‐Vaquero, María, García‐Villalba, Rocío, Cortés‐Martín, Adrián, Selma, María Victoria, Espín, Juan Carlos

“…Scope Gut microbiota dysbiosis, intestinal barrier failure, obesity, metabolic endotoxemia, and pro‐inflammatory status promote cardiovascular risk. However,…”
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Identification of Novel Urolithin Metabolites in Human Feces and Urine after the Intake of a Pomegranate Extract by García-Villalba, Rocío, Selma, María V, Espín, Juan C, Tomás-Barberán, Francisco A

“…Urolithins are bioactive gut microbiota metabolites of ellagic acid. Here, we have identified four unknown urolithins in human feces after the intake of a…”
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Gastrointestinal Simulation Model TWIN-SHIME Shows Differences between Human Urolithin-Metabotypes in Gut Microbiota Composition, Pomegranate Polyphenol Metabolism, and Transport along the Intestinal Tract by García-Villalba, Rocío, Vissenaekens, Hanne, Pitart, Judit, Romo-Vaquero, María, Espín, Juan C, Grootaert, Charlotte, Selma, María V, Raes, Katleen, Smagghe, Guy, Possemiers, Sam, Van Camp, John, Tomas-Barberan, Francisco A

“…A TWIN-SHIME system was used to compare the metabolism of pomegranate polyphenols by the gut microbiota from two individuals with different urolithin…”
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Metabolic Profiling of Dietary Polyphenols and Methylxanthines in Normal and Malignant Mammary Tissues from Breast Cancer Patients by Ávila‐Gálvez, María Ángeles, García‐Villalba, Rocío, Martínez‐Díaz, Francisco, Ocaña‐Castillo, Beatriz, Monedero‐Saiz, Tamara, Torrecillas‐Sánchez, Adela, Abellán, Beatriz, González‐Sarrías, Antonio, Espín, Juan Carlos

“…Scope Dietary polyphenols may protect against breast cancer. However, it is unknown whether polyphenols reach human malignant breast tumors in molecular forms…”
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Technological and Biotechnological Processes To Enhance the Bioavailability of Dietary (Poly)phenols in Humans by Polia, Franck, Pastor-Belda, Marta, Martínez-Blázquez, Alberto, Horcajada, Marie-Noelle, Tomás-Barberán, Francisco A, García-Villalba, Rocío

“…The health effects of (poly)­phenols (PPs) depend upon their bioavailability that, in general, is very low and shows a high interindividual variability. The…”
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Pomegranate Fruit and Juice (cv. Mollar), Rich in Ellagitannins and Anthocyanins, Also Provide a Significant Content of a Wide Range of Proanthocyanidins by Díaz-Mula, Huertas M, Tomás-Barberán, Francisco A, García-Villalba, Rocío

“…Proanthocyanidins (PAs) were characterized in husk, membranes, arils, and seeds of ‘Mollar de Elche’ pomegranate cultivar using liquid…”
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Validated Method for the Characterization and Quantification of Extractable and Nonextractable Ellagitannins after Acid Hydrolysis in Pomegranate Fruits, Juices, and Extracts by García-Villalba, Rocío, Espín, Juan Carlos, Aaby, Kjersti, Alasalvar, Cesarettin, Heinonen, Marina, Jacobs, Griet, Voorspoels, Stefan, Koivumäki, Tuuli, Kroon, Paul A, Pelvan, Ebru, Saha, Shikha, Tomás-Barberán, Francisco A

“…Pomegranates are one of the main highly valuable sources of ellagitannins. Despite the potential health benefits of these compounds, reliable data on their…”
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The Human Metabolism of Nuts Proanthocyanidins does not Reveal Urinary Metabolites Consistent with Distinctive Gut Microbiota Metabotypes by Cortés‐Martín, Adrián, Selma, María Victoria, Espín, Juan Carlos, García‐Villalba, Rocío

“…Scope The stratification of individuals according to their gut microbiota metabotypes is crucial to understand the polyphenols health effects as reported for…”
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Gut Bacteria Involved in Ellagic Acid Metabolism To Yield Human Urolithin Metabotypes Revealed by Iglesias-Aguirre, Carlos E., García-Villalba, Rocío, Beltrán, David, Frutos-Lisón, María Dolores, Espín, Juan C., Tomás-Barberán, Francisco A., Selma, María V.

“…We aimed to elucidate the gut bacteria that characterize the human urolithin metabotypes A and B (UM-A and UM-B). We report here a new bacterium isolated from…”
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Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid by Selma, María V, Beltrán, David, Luna, María C, Romo-Vaquero, María, García-Villalba, Rocío, Mira, Alex, Espín, Juan C, Tomás-Barberán, Francisco A

“…Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates…”
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Endocrine disruption in Crohn’s disease: Bisphenol A enhances systemic inflammatory response in patients with gut barrier translocation of dysbiotic microbiota products by Linares, Raquel, Fernández, Mariana F., Gutiérrez, Ana, García‐Villalba, Rocío, Suárez, Beatriz, Zapater, Pedro, Martínez‐Blázquez, José Alberto, Caparrós, Esther, Tomás‐Barberán, Francisco A., Francés, Rubén

“…The relevance of environmental triggers in Crohn's disease remains poorly explored, despite the well‐known association between industrialization and disease…”
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LC-MS Untargeted Metabolomics To Explain the Signal Metabolites Inducing Browning in Fresh-Cut Lettuce by García, Carlos J, García-Villalba, Rocío, Gil, María I, Tomas-Barberan, Francisco A

“…Enzymatic browning is one of the main causes of quality loss in lettuce as a prepared and ready-to-eat cut salad. An untargeted metabolomics approach using…”
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Detection of novel metabolites of flaxseed lignans in vitro and in vivo by Quartieri, Andrea, García-Villalba, Rocío, Amaretti, Alberto, Raimondi, Stefano, Leonardi, Alan, Rossi, Maddalena, Tomàs-Barberàn, Francisco

“…Scope This study aimed to improve the knowledge of secoisolariciresinol diglucoside (SDG) transformation by human gut microbiota. Methods and results…”
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Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter species by Selma, María V, Beltrán, David, García-Villalba, Rocío, Espín, Juan C, Tomás-Barberán, Francisco A

“…Ellagitannin and ellagic acid metabolism to urolithins in the gut shows a large human interindividual variability and this has been associated with differences…”
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