Search Results - "García‐Sancho, Javier"

Intervertebral Disc Repair by Allogeneic Mesenchymal Bone Marrow Cells: A Randomized Controlled Trial by Noriega, David C, Ardura, Francisco, Hernández-Ramajo, Rubén, Martín-Ferrero, Miguel Ángel, Sánchez-Lite, Israel, Toribio, Borja, Alberca, Mercedes, García, Verónica, Moraleda, José M, Sánchez, Ana, García-Sancho, Javier

“…BACKGROUNDDegenerative disc disease often causes severe low-back pain, a public health problem with huge economic and life quality impact. Chronic cases often…”
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The coupling of plasma membrane calcium entry to calcium uptake by endoplasmic reticulum and mitochondria by García‐Sancho, Javier

“…Key points Cross‐talk between organelles and plasma membrane Ca2+ channels modulates cytosolic Ca2+ signals in different ways. In chromaffin cells Ca2+ entry…”
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A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency by Calonge, Margarita, Pérez, Inmaculada, Galindo, Sara, Nieto-Miguel, Teresa, López-Paniagua, Marina, Fernández, Itziar, Alberca, Mercedes, García-Sancho, Javier, Sánchez, Ana, Herreras, José M.

“…Ocular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive…”
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Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening by Arduino, Daniela M., Wettmarshausen, Jennifer, Vais, Horia, Navas-Navarro, Paloma, Cheng, Yiming, Leimpek, Anja, Ma, Zhongming, Delrio-Lorenzo, Alba, Giordano, Andrea, Garcia-Perez, Cecilia, Médard, Guillaume, Kuster, Bernhard, García-Sancho, Javier, Mokranjac, Dejana, Foskett, J. Kevin, Alonso, M. Teresa, Perocchi, Fabiana

“…The mitochondrial calcium uniporter complex is essential for calcium (Ca2+) uptake into mitochondria of all mammalian tissues, where it regulates…”
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Calcium Signaling and Exocytosis in Adrenal Chromaffin Cells by Garcia, Antonio G, Garcia-De-Diego, Antonio M, Gandia, Luis, Borges, Ricardo, Garcia-Sancho, Javier

“…Instituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, and Servicio de Farmacología Clínica e Instituto Universitario de Investigación…”
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Caffeine chelates calcium in the lumen of the endoplasmic reticulum by Rojo-Ruiz, Jonathan, Rodríguez-Prados, Macarena, Delrio-Lorenzo, Alba, Alonso, María Teresa, García-Sancho, Javier

“…Cytosolic Ca signals are often amplified by massive calcium release from the endoplasmic reticulum (ER). This calcium-induced calcium release (CICR) occurs by…”
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Stem Cell Therapy for Corneal Epithelium Regeneration following Good Manufacturing and Clinical Procedures by Calonge, Margarita, García-Sancho, Javier, Fernández, Itziar, Herreras, José M., Sánchez, Ana, Ramírez, Beatriz E., Nieto-Miguel, Teresa

“…Objective. To evaluate outcomes of cultivated limbal epithelial transplantation (CLET) for management of ocular surface failure due to limbal stem cell…”
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CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons by Calatayud, Carles, Carola, Giulia, Fernández-Carasa, Irene, Valtorta, Marco, Jiménez-Delgado, Senda, Díaz, Mònica, Soriano-Fradera, Jordi, Cappelletti, Graziella, García-Sancho, Javier, Raya, Ángel, Consiglio, Antonella

“…Patient-specific induced pluripotent stem cells (iPSCs) are a powerful tool to investigate the molecular mechanisms underlying Parkinson’s disease (PD), and…”
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Imaging of Endoplasmic Reticulum Ca2+ in the Intact Pituitary Gland of Transgenic Mice Expressing a Low Affinity Ca2+ Indicator by Rojo-Ruiz, Jonathan, Navas-Navarro, Paloma, Nuñez, Lucía, García-Sancho, Javier, Alonso, María Teresa

“…The adenohypophysis contains five secretory cell types (somatotrophs, lactotrophs, thyrotrophs, corticotrophs, and gonadotrophs), each secreting a different…”
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Calcium homoeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress by Gallego-Sandín, Sonia, Alonso, María Teresa, García-Sancho, Javier

“…CALHM1 (calcium homoeostasis modulator 1), a membrane protein with similarity to NMDA (N-methyl-D-aspartate) receptor channels that localizes in the plasma…”
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The Endoplasmic Reticulum of Dorsal Root Ganglion Neurons Contains Functional TRPV1 Channels by Gallego-Sandín, Sonia, Rodríguez-García, Arancha, Alonso, María Teresa, García-Sancho, Javier

“…Transient receptor potential vanilloid type 1 (TRPV1) is a plasma membrane Ca2+ channel involved in transduction of painful stimuli. Dorsal root ganglion (DRG)…”
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Autologous bone marrow expanded mesenchymal stem cells in patellar tendinopathy: protocol for a phase I/II, single-centre, randomized with active control PRP, double-blinded clinical trial by Rodas, Gil, Soler, Robert, Balius, Ramón, Alomar, Xavier, Peirau, Xavier, Alberca, Mercedes, Sánchez, Ana, Sancho, Javier García, Rodellar, Clementina, Romero, Antonio, Masci, Lorenzo, Orozco, Lluís, Maffulli, Nicola

“…Patellar tendon overuse injuries are common in athletes. Imaging may show a change in tissue structure with tendon thickening and disruption of the…”
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Influence of HLA Matching on the Efficacy of Allogeneic Mesenchymal Stromal Cell Therapies for Osteoarthritis and Degenerative Disc Disease by García-Sancho, Javier, Sánchez, Ana, Vega, Aurelio, Noriega, David C., Nocito, Mercedes

“…The necessity for more effective therapies for chronic osteoarticular diseases has led to the development of treatments based on mesenchymal stem cells (MSCs),…”
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Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells: A Pilot Study by Orozco, Lluis, Munar, Anna, Soler, Robert, Alberca, Mercedes, Soler, Francesc, Huguet, Marina, Sentís, Joan, Sánchez, Ana, García-Sancho, Javier

“…BACKGROUNDOsteoarthritis is the most prevalent joint disease and a frequent cause of joint pain, functional loss, and disability. Osteoarthritis often becomes…”
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Bone regeneration with autologous adipose-derived mesenchymal stem cells: A reliable experimental model in rats by Barrientos, F. Javier, Redondo, Luis Miguel, Alberca, Mercedes, Sánchez, Ana María, García-Sancho, Javier

“…The adult mesenchymal stem cell (MSC) has been proposed to be the definitive tool in regenerative medicine due to its multi-differentiation potential and…”
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Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial by Vega, Aurelio, Martín-Ferrero, Miguel Angel, Del Canto, Francisco, Alberca, Mercedes, García, Veronica, Munar, Anna, Orozco, Lluis, Soler, Robert, Fuertes, Juan Jose, Huguet, Marina, Sánchez, Ana, García-Sancho, Javier

“…Osteoarthritis is the most prevalent joint disease and a common cause of joint pain, functional loss, and disability. Conventional treatments demonstrate only…”
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Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate by Núñez, Lucía, Valero, Ruth A, Senovilla, Laura, Sanz-Blasco, Sara, García-Sancho, Javier, Villalobos, Carlos

“…Store-operated Ca 2+ entry (SOCE) is a ubiquitous Ca 2+ influx pathway involved in control of multiple cellular and physiological processes including cell…”
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Rapid Changes in Anterior Pituitary Cell Phenotypes in Male and Female Mice after Acute Cold Stress by Senovilla, Laura, Núñez, Lucía, Villalobos, Carlos, García-Sancho, Javier

“…The anterior pituitary (AP) is made of five different cell types. The relative abundance and phenotype of AP cells may change in different physiological…”
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Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells: Two-Year Follow-up Results by Orozco, Lluis, Munar, Anna, Soler, Robert, Alberca, Mercedes, Soler, Francesc, Huguet, Marina, Sentís, Joan, Sánchez, Ana, García-Sancho, Javier

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Intervertebral Disc Repair by Autologous Mesenchymal Bone Marrow Cells: A Pilot Study by OROZCO, Lluis, SOLER, Robert, MORERA, Carles, ALBERCA, Mercedes, SANCHEZ, Ana, GARCIA-SANCHO, Javier

“…Degenerative disc disease may cause severe low-back pain, a large public health problem with significant economic and life quality impact. Chronic cases often…”
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