Search Results - "García‐Olmo, Damián"

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial by Panés, Julián, Prof, García-Olmo, Damián, MD, Van Assche, Gert, Prof, Colombel, Jean Frederic, Prof, Reinisch, Walter, Prof, Baumgart, Daniel C, Prof, Dignass, Axel, Prof, Nachury, Maria, MD, Ferrante, Marc, Prof, Kazemi-Shirazi, Lili, Prof, Grimaud, Jean C, Prof, de la Portilla, Fernando, Prof, Goldin, Eran, Prof, Richard, Marie Paule, MD, Leselbaum, Anne, MD, Danese, Silvio, Prof

“…Summary Background Complex perianal fistulas in Crohn's disease are challenging to treat. Allogeneic, expanded, adipose-derived stem cells (Cx601) are a…”
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Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids by Fernández‐Barral, Asunción, Costales‐Carrera, Alba, Buira, Sandra P., Jung, Peter, Ferrer‐Mayorga, Gemma, Larriba, María Jesús, Bustamante‐Madrid, Pilar, Domínguez, Orlando, Real, Francisco X., Guerra‐Pastrián, Laura, Lafarga, Miguel, García‐Olmo, Damián, Cantero, Ramón, Peso, Luis, Batlle, Eduard, Rojo, Federico, Muñoz, Alberto, Barbáchano, Antonio

“…Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but…”
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Treatment of faecal incontinence with autologous expanded mesenchymal stem cells: results of a pilot study by Portilla, Fernando, Guerrero, José Luis, Maestre, Maria Victoria, Leyva, Laura, Mera, Santiago, García‐Olmo, Damián, Rodríguez, Antonio, Mata, Rosario, Lora, Fabiola

“…Aim Management of faecal incontinence (FI) remains challenging because no definitive optimal treatment for this condition has yet been determined. Regenerative…”
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Oncological transformation in vitro of hepatic progenitor cell lines isolated from adult mice by Olivera-Salazar, Rocío, García-Arranz, Mariano, Sánchez, Aránzazu, Olmedillas-López, Susana, Vega-Clemente, Luz, Serrano, Luis Javier, Herrera, Blanca, García-Olmo, Damián

“…Colorectal cancer cells can transfer the oncogene KRAS to distant cells, predisposing them to malignant transformation (Genometastasis Theory). This process…”
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A clinico-pathological and molecular analysis reveals differences between solitary (early and late-onset) and synchronous rectal cancer by Perea, José, García, Juan L., Corchete, Luis, Tapial, Sandra, Olmedillas-López, Susana, Vivas, Alfredo, García-Olmo, Damián, Urioste, Miguel, Goel, Ajay, González-Sarmiento, Rogelio

“…Rectal cancer (RC) appears to behave differently compared with colon cancer. We aimed to analyze existence of different subtypes of RC depending on distinct…”
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Redefining synchronous colorectal cancers based on tumor clonality by Perea, José, García, Juan L., Corchete, Luis, Lumbreras, Eva, Arriba, María, Rueda, Daniel, Tapial, Sandra, Pérez, Jessica, Vieiro, Victoria, Rodríguez, Yolanda, Brandáriz, Lorena, García‐Arranz, Mariano, García‐Olmo, Damián, Goel, Ajay, Urioste, Miguel, Sarmiento, Rogelio González

“…To analyze the possible clonal origin of a part of Synchronous colorectal cancer (SCRC), we studied 104 paired‐SCRCs from 52 consecutive patients without…”
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The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer by Shelton, Phillip M., Duran, Angeles, Nakanishi, Yuki, Reina-Campos, Miguel, Kasashima, Hiroaki, Llado, Victoria, Ma, Li, Campos, Alex, García-Olmo, Damián, García-Arranz, Mariano, García-Olmo, Dolores C., Olmedillas-López, Susana, Caceres, Javier F., Diaz-Meco, Maria T., Moscat, Jorge

“…Most colorectal cancer (CRC)-related deaths are due to liver metastases. PKCζ is a tumor suppressor in CRC with reduced expression in metastasis. Given the…”
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The Current Status of Mesenchymal Stromal Cells: Controversies, Unresolved Issues and Some Promising Solutions to Improve Their Therapeutic Efficacy by García-Bernal, David, García-Arranz, Mariano, Yáñez, Rosa M, Hervás-Salcedo, Rosario, Cortés, Alfonso, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Óscar, Bueren, Juan A, García-Olmo, Damián, Moraleda, Jose M, Segovia, José C, Zapata, Agustín G

“…Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in advanced therapies with different purposes, most of which are…”
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Understanding CAR T cell therapy and its role in ovarian cancer and peritoneal carcinomatosis from ovarian cancer by Domínguez-Prieto, Víctor, Qian, Siyuan, Villarejo-Campos, Pedro, Meliga, Cecilia, González-Soares, Sara, Guijo Castellano, Ismael, Jiménez-Galanes, Santos, García-Arranz, Mariano, Guadalajara, Héctor, García-Olmo, Damián

“…Ovarian cancer is the seventh most common cancer worldwide in women and the most lethal gynecologic malignancy due to the lack of accurate screening tools for…”
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Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients by Avivar-Valderas, Alvaro, Martín-Martín, Cristina, Ramírez, Cristina, Del Río, Borja, Menta, Ramón, Mancheño-Corvo, Pablo, Ortiz-Virumbrales, Maitane, Herrero-Méndez, Ángel, Panés, Julián, García-Olmo, Damián, Castañer, José Luís, Palacios, Itziar, Lombardo, Eleuterio, Dalemans, Wilfried, DelaRosa, Olga

“…Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of…”
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Intermediate-onset colorectal cancer: A clinical and familial boundary between both early and late-onset colorectal cancer by Arriba, María, Sánchez, Carmen, Vivas, Alfredo, Nutu, O A, Rueda, Daniel, Tapial, Sandra, Rodríguez, Yolanda, Brandáriz, Lorena, García, Juan L, García-Olmo, Damián, Goel, Ajay, González-Sarmiento, Rogelio, Urioste, Miguel, Perea, José

“…Comparative studies of colorectal cancer (CRC) according to the age of onset have found differences between early-onset CRC (EOCRC) and late-onset CRC (LOCRC)…”
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Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10 by Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Oscar, Segovia, Jose-Carlos, Alvarez-Silva, Marcio, García-Arranz, Mariano, Minguez, Pablo, Del Pozo, Victoria, de Alba, Marta Rodríguez, García-Olmo, Damián, Ayuso, Carmen, Lamana, María Luisa, Bueren, Juan A, Yañez, Rosa María

“…Mesenchymal stromal cells (MSCs) constitute one of the cell types most frequently used in cell therapy. Although several studies have shown the efficacy of…”
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Detection of KRAS G12D in colorectal cancer stool by droplet digital PCR by Susana Olmedillas-López Dennis César Lévano-Linares Carmen Laura Aúz Alexandre Luz Vega-Clemente Edurne León Sánchez Alejandro Villagrasa Jaime Ruíz-Tovar Mariano García-Arranz Damián García-Olmo

“…AIM To assess KRAS G12 D mutation detection by droplet digital PCR(dd PCR) in stool-derived DNA from colorectal cancer(CRC) patients.METHODS In this study,…”
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Liquid biopsy in peritoneal fluid and plasma as a prognostic factor in advanced colorectal and appendiceal tumors after complete cytoreduction and hyperthermic intraperitoneal chemotherapy by López-Rojo, Irene, Olmedillas-López, Susana, Villarejo Campos, Pedro, Domínguez Prieto, Víctor, Barambio Buendía, Javier, Cortés Guiral, Delia, García-Arranz, Mariano, García-Olmo, Damián

“…Background: Positive cytology has been identified as an independent negative prognostic factor in patients with peritoneal metastases (PM) of colorectal…”
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Biodistribution, long-term survival, and safety of human adipose tissue-derived mesenchymal stem cells transplanted in nude mice by high sensitivity non-invasive bioluminescence imaging by Vilalta, Marta, Dégano, Irene R, Bagó, Juli, Gould, David, Santos, Mònica, García-Arranz, Mariano, Ayats, Ramon, Fuster, Carme, Chernajovsky, Yuti, García-Olmo, Damián, Rubio, Nuria, Blanco, Jerónimo

“…Cultivated murine bone marrow mesenchymal stem cells (MSCs) frequently accumulate chromosome abnormalities, become oncogenically transformed, and generate…”
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Liquid biopsy by NGS: differential presence of exons (DPE) in cell‐free DNA reveals different patterns in metastatic and nonmetastatic colorectal cancer by Olmedillas‐López, Susana, García‐Olmo, Dolores C., García‐Arranz, Mariano, Peiró‐Pastor, Ramón, Aguado, Begoña, García‐Olmo, Damián

“…Next‐generation sequencing (NGS) has been proposed as a suitable tool for liquid biopsy in colorectal cancer (CRC), although most studies to date have focused…”
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Chemical Scalpel: An Experimental Collagenase-Based Treatment for Peritoneal Adhesions by Barambio, Javier, García-Arranz, Mariano, Villarejo Campos, Pedro, Vélez Pinto, Juan Felipe, Clemente, Luz Vega, Gómez-Heras, Soledad García, Guadalajara, Héctor, García-Olmo, Damián

“…(1) Background: Abdominal adhesions are a common disease appearing after any type of abdominal surgery and may prolong surgical time and cause intestinal…”
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The role of mucin cell-free DNA detection as a new marker for the study of acellular pseudomyxoma peritonei of appendicular origin by liquid biopsy by García-Olmo, Damián, Olmedillas-López, Susana, Cortés-Guiral, Delia, Villarejo, Pedro, López Rojo, Irene, Guadalajara, Héctor, García Gómez-Heras, Soledad, García-Arranz, Mariano

“…Background: Acellular pseudomyxoma peritonei (aPMP) is a rare peritoneal malignancy characterized by the accumulation of large amounts of mucin (lacking tumor…”
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Exofucosylation of Adipose Mesenchymal Stromal Cells Alters Their Secretome Profile by García-Bernal, David, García-Arranz, Mariano, García-Guillén, Ana I, García-Hernández, Ana M, Blanquer, Miguel, García-Olmo, Damián, Sackstein, Robert, Moraleda, Jose M, Zapata, Agustín G

“…Mesenchymal stromal cells (MSCs) constitute the cell type more frequently used in many regenerative medicine approaches due to their exclusive immunomodulatory…”
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Histopathological analysis of human specimens removed from the injection area of expanded adipose-derived stem cells by García-Arranz, Mariano, Gómez-Pinedo, Ulises, Hardisson, David, Herreros, Dolores, Guadalajara, Héctor, García-Gómez, Ignacio, García-Verdugo, José Manuel, García-Olmo, Damián

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