Search Results - "García‐Lara, Silverio"

Natural Peptides Inducing Cancer Cell Death: Mechanisms and Properties of Specific Candidates for Cancer Therapeutics by Trinidad-Calderón, Plinio A, Varela-Chinchilla, Carlos Daniel, García-Lara, Silverio

“…Nowadays, cancer has become the second highest leading cause of death, and it is expected to continue to affect the population in forthcoming years…”
Get full text

Phytochemical and Nutraceutical Changes during Recurrent Selection for Storage Pest Resistance in Tropical Maize by García‐Lara, Silverio, Bergvinson, David J.

“…ABSTRACT Maize (Zea mays L.) is a staple crop used for subsistence by smallholder farmers around the world, who usually store grain for gradual use. During the…”
Get full text

Depsipeptides Targeting Tumor Cells: Milestones from In Vitro to Clinical Trials by Trinidad-Calderón, Plinio A, Varela-Chinchilla, Carlos Daniel, García-Lara, Silverio

“…Cancer is currently considered one of the most threatening diseases worldwide. Diet could be one of the factors that can be enhanced to comprehensively address…”
Get full text

An improved microscale method for extraction of phenolic acids from maize by Zavala-López, Mariana, García-Lara, Silverio

“…Phenolic acids are a major group of secondary metabolites widely distributed in plants. In the case of maize, the major proportion of these metabolites occurs…”
Get full text

Effects of parboiling and other hydrothermal treatments on the physical, functional, and nutritional properties of rice and other cereals by Rocha‐Villarreal, Verónica, Serna‐Saldivar, Sergio O., García‐Lara, Silverio

“…Background and objectives Parboiling is a hydrothermal treatment, rarely used in cereals other than rice, which consists in three sequential steps: grain…”
Get full text

Increase of tocopherols, phytosterols, and carotenoids in high‐oil subtropical maize after recurrent selection by García‐Lara, Silverio, Rodríguez‐Treviño, Abel, Ortíz‐Islas, Sofia, Preciado‐Ortíz, Ricardo E., Serna‐Saldívar, Sergio O.

Get full text

Maize hydroxycinnamic acids: unveiling their role in stress resilience and human health by González-Rodríguez, Tzitziki, García-Lara, Silverio

“…Maize production is pivotal in ensuring food security, particularly in developing countries. However, the crop encounters multiple challenges stemming from…”
Get full text

nurP28, a New-to-Nature Zein-Derived Peptide, Enhances the Therapeutic Effect of Docetaxel in Breast Cancer Monolayers and Spheroids by Trinidad-Calderón, Plinio Alejandro, López-Castillo, Laura Margarita, Gallegos-Martínez, Salvador, Trujillo-de Santiago, Grissel, García-Lara, Silverio, Álvarez, Mario Moisés

“…The development of novel cancer therapeutic strategies has garnered increasing interest in cancer research. Among the therapeutic choices, chemosensitizers…”
Get full text

Novel method for detecting and quantifying residual bran and germ tissues in refined maize grits by Rocha‐Villarreal, Verónica, Serna‐Saldívar, Sergio O., García‐Lara, Silverio

“…Background and Objectives Maize is dry‐milled to generate fine grits by separating the germ and bran fractions from the starchy endosperm. The removal without…”
Get full text

In Silico Analysis and In Vitro Characterization of the Bioactive Profile of Three Novel Peptides Identified from 19 kDa α-Zein Sequences of Maize by Díaz-Gómez, Jorge L, Neundorf, Ines, López-Castillo, Laura-Margarita, Castorena-Torres, Fabiola, Serna-Saldívar, Sergio O, García-Lara, Silverio

“…In this study, we characterized three novel peptides derived from the 19 kDa α-zein, and determined their bioactive profile in vitro and developed a structural…”
Get full text

Biomedical applications of synthetic peptides derived from venom of animal origin: A systematic review by Díaz-Gómez, Jorge L., Martín-Estal, Irene, Rivera-Aboytes, Elizabeth, Gaxiola-Muñíz, Ramón Alonso, Puente-Garza, César A., García-Lara, Silverio, Castorena-Torres, Fabiola

“…Development of therapeutic agents that have fewer adverse effects and have higher efficacy for diseases, such as cancer, metabolic disorders, neurological…”
Get full text

Application of metabolic engineering to enhance the content of alkaloids in medicinal plants by Mora-Vásquez, Soledad, Wells-Abascal, Guillermo Gael, Espinosa-Leal, Claudia, Cardineau, Guy A., García-Lara, Silverio

“…Plants are a rich source of bioactive compounds, many of which have been exploited for cosmetic, nutritional, and medicinal purposes. Through the…”
Get full text

Antioxidant Activity of Zein Hydrolysates from Zea Species and Their Cytotoxic Effects in a Hepatic Cell Culture by Díaz-Gómez, Jorge L, Ortíz-Martínez, Margarita, Aguilar, Oscar, García-Lara, Silverio, Castorena-Torres, Fabiola

“…In recent years, food proteins with bioactivity have been studied for cancer treatment. Zein peptides have shown an important set of bioactivities. This work…”
Get full text

Antiproliferative effect of peptide fractions isolated from a quality protein maize, a white hybrid maize, and their derived peptides on hepatocarcinoma human HepG2 cells by Ortiz-Martinez, Margarita, Gonzalez de Mejia, Elvira, García-Lara, Silverio, Aguilar, Oscar, Lopez-Castillo, L. Margarita, Otero-Pappatheodorou, José T.

“…•Albumins in varieties of maize provide reservoir of bioactive peptides.•Peptides from albumin maize inhibit cell growth by apoptosis of HepG2 cells.•Maize…”
Get full text

Anti-Cancer Activity of Maize Bioactive Peptides by Díaz-Gómez, Jorge L, Castorena-Torres, Fabiola, Preciado-Ortiz, Ricardo E, García-Lara, Silverio

“…Cancer is one of the main chronic degenerative diseases worldwide. In recent years, consumption of whole-grain cereals and their derivative food products has…”
Get full text

Novel Combination of the Biophysical, Nutritional, and Nutraceutical Properties in Subtropical Pigmented Maize Hybrids by Tiessen-Favier, Axel, Escalante-Aburto, Anayansi, Espinosa-Leal, Claudia, García-Lara, Silverio

“…Maize ( L.) represents the main caloric source for much of the world's population. Pigmented maize varieties are an excellent source of nutraceutical…”
Get full text

Enhancing the Antioxidant Activity of Tea ( Camellia sinensis ) Through Common Herbal Infusions by Ortiz-Islas, Sofia, Espinosa-Leal, Claudia A, González-Rodríguez, Tzitziki, García-Lara, Silverio

“…Tea is the second most widely consumed beverage globally, after water, and is known for its substantial antioxidant properties, primarily due to its phenolic…”
Get full text

Fatty acid composition and proximate analysis of improved high‐oil corn double haploid hybrids adapted to subtropical areas by Ortíz‐Islas, Sofia, García‐Lara, Silverio, Preciado‐Ortíz, Ricardo E., Serna‐Saldívar, Sergio O.

“…Background and objectives Commercial yellow corn contains approximately 4% oil whereas improved high‐oil corn (HOC) genotypes from 6% to 9% oil. The higher oil…”
Get full text

Compositional Variation in Trans -Ferulic, p -coumaric, and Diferulic Acids Levels Among Kernels of Modern and Traditional Maize ( Zea mays L.) Hybrids by Zavala-López, Mariana, Flint-García, Sherry, García-Lara, Silverio

“…Maize is one of the most heterogenous cereals worldwide in terms of yield, physical characteristics, and biochemical composition due to its natural diversity…”
Get full text

Acetone-precipitated zein protein hydrolysates from blue-maize selectively target hepatocellular carcinoma and fibroblasts in a dose-dependent manner by Trinidad-Calderón, Plinio A., López-Castillo, Laura Margarita, Díaz-Gómez, Jorge L., Muñoz Soto, Rodrigo Balam, Castorena-Torres, Fabiola, García-Lara, Silverio

“…•Acetone precipitation promoted the selection of bioactive BmapZPH.•BmapZPH could be a potential candidate for treating hepatic carcinoma.•BmapZPH decreased…”
Get full text