Search Results - "García‐Domingo, Mónica"
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1
Fluoxetine Treatment Decreases Cardiac Vagal Input and Alters the Serotonergic Modulation of the Parasympathetic Outflow in Diabetic Rats
Published in International journal of molecular sciences (20-05-2022)“…Comorbid diabetes and depression constitutes a major health problem, worsening associated cardiovascular diseases. Fluoxetine's (antidepressant) role on…”
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2
Blockade of 5‐HT2 receptors with sarpogrelate uncovers 5‐HT7 receptors inhibiting the tachycardic sympathetic drive in pithed rats
Published in Clinical and experimental pharmacology & physiology (01-03-2020)“…Our group has previously shown in pithed rats that the cardiac sympathetic drive, which produces tachycardic responses, is inhibited by 5‐HT via the activation…”
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3
5‐HT modulates the rat mesenteric vasopressor outflow by 5‐HT1D sympatholytic receptors
Published in Clinical and experimental pharmacology & physiology (01-12-2017)“…Summary 5‐hydroxytryptamine (5‐HT) modulates noradrenergic activity in different cardiovascular territories, but its effect on the mesenteric vasopressor…”
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4
Sex influence on serotonergic modulation of the vascular noradrenergic drive in rats
Published in British journal of pharmacology (03-11-2024)“…Background and Purpose In male rats, the serotonergic system modulates sympathetic outflow at vascular levels, causing sympatho‐inhibition and…”
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5
Dopamine D4 receptor subtype activation reduces the rat cardiac parasympathetic discharge
Published in Pflügers Archiv (01-12-2020)“…The dopaminergic system influences the heart rhythm by inhibiting the rat cardiac sympathetic and parasympathetic neurotransmissions through activation of D 2…”
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6
Blockade of 5-HT 2 receptors with sarpogrelate uncovers 5-HT 7 receptors inhibiting the tachycardic sympathetic drive in pithed rats
Published in Clinical and experimental pharmacology & physiology (01-03-2020)“…Our group has previously shown in pithed rats that the cardiac sympathetic drive, which produces tachycardic responses, is inhibited by 5-HT via the activation…”
Get full text
Journal Article -
7
5-HT modulates the rat mesenteric vasopressor outflow by 5-HT 1D sympatholytic receptors
Published in Clinical and experimental pharmacology & physiology (01-12-2017)“…5-hydroxytryptamine (5-HT) modulates noradrenergic activity in different cardiovascular territories, but its effect on the mesenteric vasopressor outflow has…”
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8
Chronic sarpogrelate treatment improves renal sympathetic hyperactivity in experimental diabetes
Published in Biomedicine & pharmacotherapy (01-07-2024)“…Diabetes and derived complications, especially diabetic nephropathy and neuropathy annually cause great morbimortality worldwide. 5-hydroxytryptamine (5-HT)…”
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9
Vascular sympathetic neurotransmission and its serotonergic regulation are modified by chronic fluoxetine treatment
Published in Journal of pharmacological sciences (01-09-2021)“…Given the interconnection between depressive and cardiovascular disorders, we investigated whether antidepressant treatment (fluoxetine) modifies the…”
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10
Effect of sarpogrelate treatment on 5-HT modulation of vascular sympathetic innervation and platelet activity in diabetic rats
Published in Biomedicine & pharmacotherapy (01-09-2022)“…This study aimed to investigate whether the 5-HT2 receptor blockade alters the 5-HT effect on vascular sympathetic neurotransmission and platelet activation in…”
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11
Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats
Published in Scientific reports (09-11-2020)“…5-HT inhibits cardiac sympathetic neurotransmission in normoglycaemic rats, via 5-HT 1B , 5-HT 1D and 5-HT 5A receptor activation. Since type 1 diabetes…”
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12
Renal Sympathetic Hyperactivity in Diabetes Is Modulated by 5-HT1D Receptor Activation via NO Pathway
Published in International journal of molecular sciences (10-01-2023)“…Renal vasculature, which is highly innervated by sympathetic fibers, contributes to cardiovascular homeostasis. This renal sympathetic outflow is inhibited by…”
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13
Hypertension exhibits 5-HT4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature
Published in Hypertension research (01-05-2019)“…Sympathetic overdrive is a key player in hypertension, where the mesenteric vasculature plays a relevant role in modulating blood pressure. Although 5-HT…”
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14
Hypertension exhibits 5-HT 4 receptor as a modulator of sympathetic neurotransmission in the rat mesenteric vasculature
Published in Hypertension research (01-05-2019)“…Sympathetic overdrive is a key player in hypertension, where the mesenteric vasculature plays a relevant role in modulating blood pressure. Although 5-HT…”
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15
Renal Sympathetic Hyperactivity in Diabetes Is Modulated by 5-HT 1D Receptor Activation via NO Pathway
Published in International journal of molecular sciences (10-01-2023)“…Renal vasculature, which is highly innervated by sympathetic fibers, contributes to cardiovascular homeostasis. This renal sympathetic outflow is inhibited by…”
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Journal Article -
16
Role of peripheral 5-HT 5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats
Published in Scientific reports (09-11-2020)“…5-HT inhibits cardiac sympathetic neurotransmission in normoglycaemic rats, via 5-HT , 5-HT and 5-HT receptor activation. Since type 1 diabetes impairs the…”
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Journal Article -
17
Dopamine D 4 receptor subtype activation reduces the rat cardiac parasympathetic discharge
Published in Pflügers Archiv (01-12-2020)“…The dopaminergic system influences the heart rhythm by inhibiting the rat cardiac sympathetic and parasympathetic neurotransmissions through activation of D…”
Get full text
Journal Article -
18
Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes
Published in Life sciences (1973) (15-03-2022)“…This study investigated whether fluoxetine treatment changes the 5-HT regulation on vascular sympathetic neurotransmission in type 1 diabetes. Four-week…”
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