Search Results - "García‐Aranda, Natalia"

In Vivo Antitumor and Antimetastatic Efficacy of a Polyacetal‐Based Paclitaxel Conjugate for Prostate Cancer Therapy by Fernández, Yolanda, Movellan, Julie, Foradada, Laia, Giménez, Vanessa, García‐Aranda, Natalia, Mancilla, Sandra, Armiñán, Ana, Borgos, Sven Even, Hyldbakk, Astrid, Bogdanska, Anna, Gobbo, Oliviero L., Prina‐Mello, Adriele, Ponti, Jessica, Calzolai, Luigi, Zagorodko, Oleksandr, Gallon, Elena, Niño‐Pariente, Amaya, Paul, Alison, Schwartz Jr, Simó, Abasolo, Ibane, Vicent, María J.

“…Prostate cancer (PCa), one of the leading causes of cancer‐related deaths, currently lacks effective treatment for advanced‐stage disease. Paclitaxel (PTX) is…”
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Selectively Targeting Breast Cancer Stem Cells by 8-Quinolinol and Niclosamide by Cámara-Sánchez, Patricia, Díaz-Riascos, Zamira V., García-Aranda, Natalia, Gener, Petra, Seras-Franzoso, Joaquin, Giani-Alonso, Micaela, Royo, Miriam, Vázquez, Esther, Schwartz, Simó, Abasolo, Ibane

“…Cancer maintenance, metastatic dissemination and drug resistance are sustained by cancer stem cells (CSCs). Triple negative breast cancer (TNBC) is the breast…”
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Extracellular vesicles from recombinant cell factories improve the activity and efficacy of enzymes defective in lysosomal storage disorders by Seras‐Franzoso, Joaquin, Díaz‐Riascos, Zamira V., Corchero, José Luis, González, Patricia, García‐Aranda, Natalia, Mandaña, Mònica, Riera, Roger, Boullosa, Ana, Mancilla, Sandra, Grayston, Alba, Moltó‐Abad, Marc, Garcia‐Fruitós, Elena, Mendoza, Rosa, Pintos‐Morell, Guillem, Albertazzi, Lorenzo, Rosell, Anna, Casas, Josefina, Villaverde, Antonio, Schwartz, Simó, Abasolo, Ibane

“…In the present study the use of extracellular vesicles (EVs) as vehicles for therapeutic enzymes in lysosomal storage disorders was explored. EVs were isolated…”
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Polymer Capsules as a Theranostic Tool for a Universal In Vitro Screening Assay-The Case of Lysosomal Storage Diseases by Nazarenus, Moritz, Abasolo, Ibane, García-Aranda, Natalia, Voccoli, Vladimir, Rejman, Joanna, Cecchini, Marco, Schwartz Jr, Simó, Rivera_Gil, Pilar, Parak, Wolfgang J.

“…Lysosomal storage disorders are rare genetic diseases characterized by a lysosomal enzyme deficiency. The defect leads to an accumulation of normally degraded…”
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Theranostics: Polymer Capsules as a Theranostic Tool for a Universal In Vitro Screening Assay-The Case of Lysosomal Storage Diseases (Part. Part. Syst. Charact. 11/2015) by Nazarenus, Moritz, Abasolo, Ibane, García-Aranda, Natalia, Voccoli, Vladimir, Rejman, Joanna, Cecchini, Marco, Schwartz Jr, Simó, Rivera_Gil, Pilar, Parak, Wolfgang J.

“…Polymer multilayer capsules are used by P. Rivera_Gil, W. J. Parak, and co‐workers for concomitant pH‐sensing and enzyme delivery to lysosomes in the framework…”
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Impact of Chemical Composition on the Nanostructure and Biological Activity of α‑Galactosidase‑Loaded Nanovesicles for Fabry Disease Treatment by Tomsen-Melero, Judit, Passemard, Solène, García-Aranda, Natalia, Díaz-Riascos, Zamira Vanessa, González-Rioja, Ramon, Nedergaard Pedersen, Jannik, Lyngsø, Jeppe, Merlo-Mas, Josep, Cristóbal-Lecina, Edgar, Corchero, José Luis, Pulido, Daniel, Cámara-Sánchez, Patricia, Portnaya, Irina, Ionita, Inbal, Schwartz, Simó, Veciana, Jaume, Sala, Santi, Royo, Miriam, Córdoba, Alba, Danino, Dganit, Pedersen, Jan Skov, González-Mira, Elisabet, Abasolo, Ibane, Ventosa, Nora

“…Fabry disease is a rare lysosomal storage disorder characterized by a deficiency of α-galactosidase A (GLA), a lysosomal hydrolase. The enzyme replacement…”
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Highly Versatile Polyelectrolyte Complexes for Improving the Enzyme Replacement Therapy of Lysosomal Storage Disorders by Giannotti, Marina I, Abasolo, Ibane, Oliva, Mireia, Andrade, Fernanda, García-Aranda, Natalia, Melgarejo, Marta, Pulido, Daniel, Corchero, José L, Fernández, Yolanda, Villaverde, Antonio, Royo, Miriam, García-Parajo, María F, Sanz, Fausto, Schwartz, Simó

“…Lysosomal storage disorders are currently treated by enzyme replacement therapy (ERT) through the direct administration of the unprotected recombinant protein…”
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Polymeric micelles targeted against CD44v6 receptor increase niclosamide efficacy against colorectal cancer stem cells and reduce circulating tumor cells in vivo by Andrade, Fernanda, Rafael, Diana, Vilar-Hernández, Mireia, Montero, Sara, Martínez-Trucharte, Francesc, Seras-Franzoso, Joaquin, Díaz-Riascos, Zamira V., Boullosa, Ana, García-Aranda, Natalia, Cámara-Sánchez, Patricia, Arango, Diego, Nestor, Marika, Abasolo, Ibane, Sarmento, Bruno, Schwartz, Simó

“…Colorectal cancer (CRC) is a highly prevalent disease worldwide. Patient survival is hampered by tumor relapse and the appearance of drug-resistant metastases,…”
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Application of Quality by Design to the robust preparation of a liposomal GLA formulation by DELOS-susp method by Merlo-Mas, Josep, Tomsen-Melero, Judit, Corchero, José-Luis, González-Mira, Elisabet, Font, Albert, Pedersen, Jannik N., García-Aranda, Natalia, Cristóbal-Lecina, Edgar, Alcaina-Hernando, Marta, Mendoza, Rosa, Garcia-Fruitós, Elena, Lizarraga, Teresa, Resch, Susanne, Schimpel, Christa, Falk, Andreas, Pulido, Daniel, Royo, Miriam, Schwartz, Simó, Abasolo, Ibane, Pedersen, Jan Skov, Danino, Dganit, Soldevila, Andreu, Veciana, Jaume, Sala, Santi, Ventosa, Nora, Córdoba, Alba

“…•Robust preparation of liposomal formulation by DELOS-susp method.•Implementation of Quality by Design methodology to liposomes preparation.•Influence of…”
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Improved pharmacokinetic profile of lipophilic anti-cancer drugs using ανβ3-targeted polyurethane-polyurea nanoparticles by Rocas, Pau, Fernández, Yolanda, García-Aranda, Natalia, Foradada, Laia, Calvo, Pilar, Avilés, Pablo, Guillén, María José, Schwartz, Simó, Rocas, Josep, Albericio, Fernando, Abasolo, Ibane

“…Glutathione degradable polyurethane-polyurea nanoparticles (PUUa NP) with a disulfide-rich multiwalled structure and a cyclic RGD peptide as a targeting moiety…”
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Design of chalcogen-containing norepinephrines: efficient GPx mimics and strong cytotoxic agents against HeLa cells by Marset, Azucena, Begines, Paloma, López, Óscar, Maya, Inés, García-Aranda, Natalia, Schwartz, Simó, Abasolo, Ibane, Fernández-Bolaños, José G

“…Numerous chronic diseases exhibit multifactorial etiologies, so focusing on a single therapeutic target is usually an inadequate treatment; instead,…”
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Extracellular vesicles increase the enzymatic activity of lysosomal proteins and improve the efficacy of enzyme replacement therapy in Fabry disease by Abasolo, Ibane, Seras-Franzoso, Joaquin, Díaz-Riascos, Zamira Vanessa, Corchero, José Luis, González, Patricia, García-Aranda, Natalia, Mandaña, Monica, Riera, Roger, Boullosa, Ana, Mancilla, Sandra, Grayston, Alba, Moltó-Abad, Marc, Garcia-Fruitós, Elena, Mendoza, Rosa, Pintos-Morell, Guillem, Albertazzi, Lorenzo, Rosell, Anna, Casas, Josefina, Villaverde, Antonio, Schwartz, Simó

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Targeted nanoliposomes for the treatment of Fabry disease by Abasolo, Ibane, Lechado, Anna, García-Aranda, Natalia, Bueno, Dolores, Ortega, David, González-Mira, Elisabeth, Passemard, Solène, Díaz-Riascos, Zamira Vanessa, Mendoza, Rosa, Corchero, José Luis, Moltó-Abad, Marc, Cristóbal-Lecina, Edgar, Pulido, Daniel, Casas, Josefina, Royo, Miriam, Pintos-Morell, Guillem, Veciana, Jaume, Ventosa, Nora, Schwartz, Simó

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Highly Versatile Polyelectrolyte Complexes for Improving the Enzyme Replacement Therapy of Lysosomal Storage Disorders by Giannotti, Marina Ines, Abasolo, Ibane, Oliva, Mireia (Oliva Herrera), Andrade, Fernanda, García-Aranda, Natalia, Melgarejo Diaz, Marta, Pulido, Daniel, Corchero, José L, Fernández Amurgo, Yolanda, Villaverde, Antonio, Royo Expósito, Miriam, García-Parajo, María F, Sanz Carrasco, Fausto, Schwartz Navarro, Simó

“…Lysosomal storage disorders are currently treated by enzyme replacement therapy (ERT) through the direct administration of the unprotected recombinant protein…”
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Highly Versatile Polyelectrolyte Complexes for Improving the Enzyme Replacement Therapy of Lysosomal Storage Disorders by Giannotti, Marina Ines, Abasolo, Ibane, Oliva, Mireia (Oliva Herrera), Andrade, Fernanda, García-Aranda, Natalia, Melgarejo Diaz, Marta, Pulido, Daniel, Corchero, José L, Fernández Amurgo, Yolanda, Villaverde, Antonio, Royo Expósito, Miriam, García-Parajo, María F, Sanz Carrasco, Fausto, Schwartz Navarro, Simó

“…Lysosomal storage disorders are currently treated by enzyme replacement therapy (ERT) through the direct administration of the unprotected recombinant protein…”
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Efficient EFGR mediated siRNA delivery to breast cancer cells by Cetuximab functionalized Pluronic® F127/Gelatin by Rafael, Diana, Martínez, Francesc, Andrade, Fernanda, Seras-Franzoso, Joaquin, Garcia-Aranda, Natalia, Gener, Petra, Sayós, Joan, Arango, Diego, Abasolo, Ibane, Schwartz, Simó

“…•F127 is efficiently carboxylated through the maleic anhydride method (PM F127:COOH).•Carboxylated F127 is efficiently conjugated with Cetuximab (PM…”
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Are bacterial growth and/or chemotaxis increased by filler injections? Implications for the pathogenesis and treatment of filler-related granulomas by Alijotas-Reig, Jaume, Miró-Mur, Francesc, Planells-Romeu, Irene, Garcia-Aranda, Natalia, Garcia-Gimenez, Victor, Vilardell-Tarrés, Miquel

“…As microbial agents have been associated with late adverse effects related to fillers antibiotic treatment has been envisaged. To determine whether…”
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