Search Results - "García‐Altares, María"
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What are we imaging? Software tools and experimental strategies for annotation and identification of small molecules in mass spectrometry imaging
Published in Mass spectrometry reviews (01-09-2023)“…Mass spectrometry imaging (MSI) has become a widespread analytical technique to perform nonlabeled spatial molecular identification. The Achilles' heel of MSI…”
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A Pair of Bacterial Siderophores Releases and Traps an Intercellular Signal Molecule: An Unusual Case of Natural Nitrone Bioconjugation
Published in Angewandte Chemie International Edition (02-01-2019)“…In microbial interactions bacteria employ diverse molecules with specific functions, such as sensing the environment, communication with other microbes or…”
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Silicon‐Based Laser Desorption Ionization Mass Spectrometry for the Analysis of Biomolecules: A Progress Report
Published in Advanced functional materials (01-11-2019)“…Matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) is widely used in the biomedical field for the label‐free analysis of molecules such…”
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Gold Nanoparticle-Assisted Black Silicon Substrates for Mass Spectrometry Imaging Applications
Published in ACS nano (23-06-2020)“…Mass spectrometry imaging (MSI) based on matrix-assisted laser desorption ionization (MALDI) is widely used in proteomics. However, matrix-free technologies…”
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Injury‐Triggered Blueing Reactions of Psilocybe “Magic” Mushrooms
Published in Angewandte Chemie International Edition (20-01-2020)“…Upon injury, psychotropic psilocybin‐producing mushrooms instantly develop an intense blue color, the chemical basis and mode of formation of which has…”
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Induced Chemical Defense of a Mushroom by a Double‐Bond‐Shifting Polyene Synthase
Published in Angewandte Chemie International Edition (15-05-2017)“…The antilarval mushroom polyenes 18‐methyl‐19‐oxoicosaoctaenoic acid and 20‐methyl‐21‐oxodocosanonaenoic acid appear in response to injury of the mycelium of…”
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Perspective on Multimodal Imaging Techniques Coupling Mass Spectrometry and Vibrational Spectroscopy: Picturing the Best of Both Worlds
Published in Analytical chemistry (Washington) (27-04-2021)“…Studies on complex biological phenomena often combine two or more imaging techniques to collect high-quality comprehensive data directly in situ, preserving…”
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SALDI-MS and SERS Multimodal Imaging: One Nanostructured Substrate to Rule Them Both
Published in Analytical chemistry (Washington) (15-02-2022)“…Imaging techniques based on mass spectrometry or spectroscopy methods inform in situ about the chemical composition of biological tissues or organisms, but…”
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Multimodal Molecular Imaging and Identification of Bacterial Toxins Causing Mushroom Soft Rot and Cavity Disease
Published in Chembiochem : a European journal of chemical biology (01-10-2021)“…Soft rot disease of edible mushrooms leads to rapid degeneration of fungal tissue and thus severely affects farming productivity worldwide. The bacterial…”
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Antagonistic bacteria disrupt calcium homeostasis and immobilize algal cells
Published in Nature communications (24-11-2017)“…Photosynthetic unicellular organisms, known as microalgae, are key contributors to carbon fixation on Earth. Their biotic interactions with other microbes…”
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rMSIannotation: A peak annotation tool for mass spectrometry imaging based on the analysis of isotopic intensity ratios
Published in Analytica chimica acta (01-08-2021)“…Mass spectrometry imaging (MSI) consist of spatially located spectra with thousands of peaks. Only a fraction of these peaks corresponds to unique monoisotopic…”
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Raman2imzML converts Raman imaging data into the standard mass spectrometry imaging format
Published in BMC bioinformatics (09-10-2020)“…Multimodal imaging that combines mass spectrometry imaging (MSI) with Raman imaging is a rapidly developing multidisciplinary analytical method used by a…”
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Rapid Screening of Polyol Polyketides from Marine Dinoflagellates
Published in Analytical chemistry (Washington) (18-10-2022)“…Dinoflagellate-derived polyketides are typically large molecules (>1000 Da) with complex structures, potent bioactivities, and high toxicities. Their discovery…”
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Opisthobranch grazing results in mobilisation of spherulous cells and re-allocation of secondary metabolites in the sponge Aplysina aerophoba
Published in Scientific reports (14-12-2020)“…Sponges thrive in marine benthic communities due to their specific and diverse chemical arsenal against predators and competitors. Yet, some animals…”
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Lipidomics Reveals Myocardial Lipid Composition in a Murine Model of Insulin Resistance Induced by a High-Fat Diet
Published in International journal of molecular sciences (26-02-2024)“…Ectopic fat accumulation in non-adipose tissues is closely related to diabetes-related myocardial dysfunction. Nevertheless, the complete picture of the lipid…”
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Synergistic activity of cosecreted natural products from amoebae-associated bacteria
Published in Proceedings of the National Academy of Sciences - PNAS (10-04-2018)“…Investigating microbial interactions from an ecological perspective is a particularly fruitful approach to unveil both new chemistry and bioactivity. Microbial…”
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Mapping Natural Dyes in Archeological Textiles by Imaging Mass Spectrometry
Published in Scientific reports (20-02-2019)“…Organic dyes of animal and plant origin have often been used by our ancestors to create textiles with polychromic ornamental patterns, and dyestuff analyses…”
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Confirmation of pinnatoxins and spirolides in shellfish and passive samplers from Catalonia (Spain) by liquid chromatography coupled with triple quadrupole and high-resolution hybrid tandem mass spectrometry
Published in Marine drugs (23-06-2014)“…Cyclic imines are lipophilic marine toxins that bioaccumulate in seafood. Their structure comprises a cyclic-imino moiety, responsible for acute neurotoxicity…”
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Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases
Published in Chemical science (Cambridge) (2019)“…Modular biosynthetic machineries such as polyketide synthases (PKSs) or nonribosomal peptide synthetases (NRPSs) give rise to a vast structural diversity of…”
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rMSIfragment: improving MALDI-MSI lipidomics through automated in-source fragment annotation
Published in Journal of cheminformatics (15-09-2023)“…Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging (MALDI-MSI) spatially resolves the chemical composition of tissues. Lipids are of…”
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