Search Results - "García, Néstor H"

Monosialoganglioside GM1 reduces toxicity of Ptx and increase anti-metastasic effect in a murine mammary cancer model by Leonhard, Victoria, Alasino, Roxana V., Pasqualini, María E., Cremonezzi, David C., García, Néstor H., Beltramo, Dante M.

“…Having demonstrated the ability of monosialoganglioside GM1 micelles as oncology drug transporter, this work focuses on evaluating its application in an in…”
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Eicosapentaenoic acid prevents salt sensitivity in diabetic rats and decreases oxidative stress by Vara-Messler, Marianela, Mukdsi, Jorge H., Osieki, Natalia I., Benizio, Evangelina, Repossi, Gastón M., Ajayi, Ebenezer I.O., García, Néstor H.

“…•Salt Sensitivity prevention in Diabetes Mellitus.•Hypertension is an important risk factor for cardiovascular disease and mortality, characterized by a slow…”
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Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α by Cabral, Pablo D, Silva, Guillermo B, Baigorria, Sandra T, Juncos, Luis I, Ajayi, Ebenezer I O, García, Néstor H

“…Sodium chloride (NaCl) reabsorption in the cortical thick ascending limb (cTAL) is regulated by opposing effects. Nitric oxide (NO) inhibits NaCl reabsorption…”
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High Concentrations of Sodium Chloride Improve Microbicidal Activity of Ibuprofen against Common Cystic Fibrosis Pathogens by Muñoz, Adrián J, Alasino, Roxana V, Garro, Ariel G, Heredia, Valeria, García, Néstor H, Cremonezzi, David C, Beltramo, Dante M

“…Ibuprofen (IBU-H), a widely used anti-inflammatory, also shows a marked antimicrobial effect against several bacterial species, including those involved in…”
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Risk of Vascular Disease in Premenopausal Women With Diabetes Mellitus by García, Néstor H., MD, PhD, Pérez, Hernán A., MD, Spence, J. David, MD, FRCPC, FAHA, Armando, Luis J., MD

“…Abstract Purpose The aims of this study were (1) to estimate the prevalence of cardiovascular disease risk factors among premenopausal and menopausal…”
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Increased carotid plaque burden in patients with family medical history of premature cardiovascular events in the absence of classical risk factors by Atkins, Paul W, Perez, Hernán A, Spence, J David, Muñoz, Sonia E, Armando, Luis J, García, Néstor H

“…The hypothesis that relates atherosclerosis to traditional risk factors (TRF) seems to be not as adequate as previously thought; other risk factors (RF) need…”
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Reversal of SARS-CoV2-Induced Hypoxia by Nebulized Sodium Ibuprofenate in a Compassionate Use Program by Salva, Oscar, Doreski, Pablo A., Giler, Celia S., Quinodoz, Dario C., Guzmán, Lucia G., Muñoz, Sonia E., Carrillo, Mariana N., Porta, Daniela J., Ambasch, Germán, Coscia, Esteban, Diaz, Jorge L. Tambini, Bueno, Germán D., Fandi, Jorge O., Maldonado, Miriam A., Peña Chiappero, Leandro E., Fournier, Fernando, Pérez, Hernán A., Quiroga, Mauro A., Sala Mercado, Javier A., Martínez Picco, Carlos, Beltrán, Marcelo Alejandro, Argañarás, Luis A., Ríos, Nicolás Martínez, Kalayan, Galia I., Beltramo, Dante M., García, Néstor H.

“…Introduction Sodium ibuprofenate in hypertonic saline (NaIHS) administered directly to the lungs by nebulization and inhalation has antibacterial and…”
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Atorvastatin improves sodium handling and decreases blood pressure in salt-loaded rats with chronic renal insufficiency by Juncos, Luis I., M.D., Ph.D, Martín, Fernando L., M.D, Baigorria, Sandra T., Lab.Tech, Pasqualini, María E., Ph.D, Fiore, María C., Ph.D, Eynard, Aldo R., M.D., Ph.D, Juncos, Luis A., M.D, García, Néstor H., M.D., Ph.D

“…Abstract Objective Oxidative stress and inflammation seem to mediate the cardiovascular risks associated with salt sensitivity. Because hydroxymethyl glutaryl…”
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8-iso-prostaglandin-F2α stimulates chloride transport in thick ascending limbs: role of cAMP and protein kinase A by Cabral, Pablo D, Silva, Guillermo B, Baigorria, Sandra T, Juncos, Luis A, Juncos, Luis I, García, Néstor H

“…Salt reabsorption by the loop of Henle controls NaCl handling and blood pressure regulation. Increased oxidative stress stimulates NaCl transport in one…”
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Obesidad central, sarcopenia y conductas sedentarias en el riesgo cardiovascular por score Framingham y área total de placa carotídea by Viola, Lorena, García, Néstor Horacio, Pérez, Hernán A., Armando, Luis J., Carrillo, Mariana N., Muñoz, Sonia E., Aballay, Laura R.

“…Antecedentes: las enfermedades cardiovasculares son la principal causa de morbimortalidad mundial. La obesidad, sarcopenia, actividad física insuficiente y las…”
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Pharmacoinformatics studies of coenzyme Q10 and potassium polyacrylate on angiotensin-converting enzyme associated with hypertension by Adeoye, Akinwunmi O., Porta, Daniela J., Rivoira, María A., Garcia, Néstor H.

“…Coenzyme Q10's (CoQ10) favorable impact on cardiovascular diseases risk factors like hypertension and atherosclerosis is linked to the antioxidant action of…”
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Nitric Oxide-Induced Inhibition of Transport by Thick Ascending Limbs From Dahl Salt-Sensitive Rats by García, Néstor H, Plato, Craig F, Stoos, Barbara A, Garvin, Jeffrey L

“…The factor responsible for salt sensitivity of blood pressure in Dahl rats is unclear but presumably resides in the kidney. We tested the hypotheses that (1)…”
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Mechanism of the Nitric Oxide-Induced Blockade of Collecting Duct Water Permeability by Garcia, Nestor H, Stoos, Barbara A, Carretero, Oscar A, Garvin, Jeffrey L

“…Nitric oxide has a diuretic effect in vivo. We have shown that nitric oxide inhibits antidiuretic hormone-stimulated osmotic water permeability in the…”
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Atherosclerosis plaque area reduction: working hypothesis to prevent cardiovascular event by Perez, Hernán A., Allende, Gustavo Flores, Ajayi, Ebenezer I. O., Porta, Daniela J., García, Néstor H.

“…Cardiovascular events are the leading cause of death worldwide. In this sense, cardiovascular diseases (CVD) are the main products of atherosclerosis (ATR),…”
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Hyperkalemia, Renal Failure, and Converting-Enzyme Inhibition: An Overrated Connection by García, Néstor H, Baigorria, Sandra T, Juncos, Luis I

“…Hyperkalemia is widely viewed as a common complication of ACE inhibition in azotemic patients. These renal failure patients are the patients who benefit most…”
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Angiotensin II and Anti Diuretic Hormone Exert Synergistic Effects on Thick Ascending Limb Transport in Spontaneously Hypertensive Rats by Silva, Guillermo B, Juncos, Luis I, Garcia, Néstor H

“…Sodium reabsorption is increased in the thick ascending limb (TAL) of Henle in several hypertensive models. In this segment, while transport is increased by…”
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Ibuprofen, a traditional drug that may impact the course of COVID-19 new effective formulation in nebulizable solution by García, Néstor H., Porta, Daniela J., Alasino, Roxana V., Muñoz, Sonia E., Beltramo, Dante M.

“…The traditional formulation of ibuprofen is poorly soluble in water, so the administered dose must be 10 times higher than the dose required for a therapeutic…”
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An intensive follow-up in subjects with cardiometabolic high-risk by Pérez, Hernán A., Adeoye, Akinwunmi O., Aballay, Laura, Armando, Luis A., García, Néstor H.

“…Addressing chronic problems requires a model of care that promotes self-management of the disease and facilitates adherence to treatment. This project was…”
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Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors by Silva, Guillermo B, Atchison, Douglas K, Juncos, Luis I, García, Néstor H

“…The energy required for active Na chloride reabsorption in the thick ascending limb (TAL) depends on oxygen consumption and oxidative phosphorylation (OXP). In…”
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The Antihypertensive Actions of Statins: Modulation by Salt Intake by Juncos, Luis I., Juncos, Luis A., García, Nestor H.

“…Hydroxy methyl glutaryl CoA inhibitors (statins) are the agents most frequently used to reduce elevated serum cholesterol. In addition to their cholesterol…”
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