Search Results - "García, Leandro"
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Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy
Published in Journal of medical genetics (01-09-2013)“…Peripheral neuropathy is the dose limiting toxicity of paclitaxel, a chemotherapeutic drug widely used to treat solid tumours. This toxicity exhibits great…”
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The miR-200 family controls β-tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients
Published in Endocrine-related cancer (01-02-2011)“…Ovarian cancer remains one of the leading causes of cancer deaths. Thus, new biomarkers predictive of response to the standard paclitaxel–carboplatin treatment…”
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Hsa‐miR‐139‐5p is a prognostic thyroid cancer marker involved in HNRNPF‐mediated alternative splicing
Published in International journal of cancer (15-01-2020)“…It is critical to identify biomarkers and functional networks associated with aggressive thyroid cancer to anticipate disease progression and facilitate…”
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Tumoral and tissue-specific expression of the major human β-tubulin isotypes
Published in Cytoskeleton (Hoboken, N.J.) (01-04-2010)“…The β‐tubulins are microtubule components encoded by a multigene family, which produces slightly different proteins with complex expression patterns. Several…”
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Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma
Published in Annals of oncology (01-09-2013)“…Previous studies suggest that expression of hypoxia markers may be associated with response to antiangiogenic drugs. Thus, we aimed to identify predictors of…”
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Internacionalismos en disputa al interior de la Unión Sindical Argentina (1922-1924)
Published in Sociohistórica : Cuadernos del CISH (01-03-2024)“…Este artículo analiza los debates producidos en la Unión Sindical Argentina (USA) acerca de la posición que debía adoptar la central en relación a las…”
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An stated preference analysis of Spanish freight forwarders modal choice on the south-west Europe Motorway of the Sea
Published in Transport policy (2011)“…This paper aims to contribute towards the design of effective freight transport policy by means of empirical analysis. In order to do so, a stated preference…”
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Research Resource: Transcriptional Profiling Reveals Different Pseudohypoxic Signatures in SDHB and VHL-Related Pheochromocytomas
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2010)“…The six major genes involved in hereditary susceptibility for pheochromocytoma (PCC)/paraganglioma (PGL) (RET, VHL, NF1, SDHB, SDHC, and SDHD) have been…”
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Polymeric films prepared from starch and a crosslinker extracted from avocado seeds
Published in Journal of applied polymer science (15-08-2022)“…The avocado seeds, considered as waste, were used for the extraction of oil rich in pentosans and starch. The avocado starch (AS) and a commercial starch (CS)…”
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Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family
Published in Genes chromosomes & cancer (01-11-2011)“…Hereditary primary hyperparathyroidism (HPT) may develop as a solitary endocrinopathy (FIHP) or as part of multiple endocrine neoplasia Type 1, multiple…”
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Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis
Published in Endocrine-related cancer (01-03-2010)“…Therapeutic options for patients with metastatic medullary thyroid carcinoma (MTC) are limited due to lack of effective treatments. Thus, there is a need to…”
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Microstructured TiO2 coatings by anodization of Ti6Al4V with oxalic acid
Published in Applied physics. A, Materials science & processing (01-02-2023)“…Natural oxidation of Titanium allows the formation of a TiO 2 coating that is known to present relevant tribological and photocatalytic properties. These…”
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Biocompatibility and Surface Properties of TiO₂ Thin Films Deposited by DC Magnetron Sputtering
Published in Materials (27-05-2014)“…We present the study of the biocompatibility and surface properties of titanium dioxide (TiO₂) thin films deposited by direct current magnetron sputtering…”
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Cytotoxicity Evaluation of Anatase and Rutile TiO₂ Thin Films on CHO-K1 Cells in Vitro
Published in Materials (26-07-2016)“…Cytotoxicity of titanium dioxide (TiO₂) thin films on Chinese hamster ovary (CHO-K1) cells was evaluated after 24, 48 and 72 h of culture. The TiO₂ thin films…”
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Integrative analysis of miRNA and mRNA expression profiles in pheochromocytoma and paraganglioma identifies genotype-specific markers and potentially regulated pathways
Published in Endocrine-related cancer (01-08-2013)“…Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare neuroendocrine neoplasias of neural crest origin that can be part of several inherited syndromes…”
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MAML3-fusions modulate vascular and immune tumour microenvironment and confer high metastatic risk in pheochromocytoma and paraganglioma
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (29-08-2024)“…Pheochromocytomas and paragangliomas are rare neuroendocrine tumours. Around 20–25 % of patients develop metastases, for which there is an urgent need of…”
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Molecular characterisation of a common SDHB deletion in paraganglioma patients
Published in Journal of medical genetics (01-04-2008)“…Hereditary susceptibility to familial paraganglioma syndromes is mainly due to mutations in one of six genes, including three of the four genes encoding the…”
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Genetic variation in the SLC19A1 gene and methotrexate toxicity in rheumatoid arthritis patients
Published in Pharmacogenomics (01-11-2012)“…We investigated the clinical relevance of SLC19A1 genetic variability for methotrexate (MTX) toxicity in rheumatoid arthritis patients using a haplotype-based…”
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Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology
Published in Journal of Alzheimer's disease (01-01-2016)“…Alzheimer's disease (AD) is characterized by a long pre-clinical phase (20-30 years), during which significant brain pathology manifests itself. Disease…”
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Design of Acetaldehyde Gas Sensor Based on Piezoelectric Multilayer Microelectromechanical System Resonator
Published in Micromachines (Basel) (28-07-2024)“…Acetaldehyde is a volatile organic compound that can cause damage at the cellular and genomic levels. The monitoring of acetaldehyde gas at low concentrations…”
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