Search Results - "García, Isela"

QSAR, docking, and CoMFA studies of GSK3 inhibitors by García, Isela, Fall, Yagamare, Gómez, Generosa

“…GSK-3 inhibitors are interesting candidates to develop Anti-Alzheimer compounds. GSK-3β are also interesting as Anti-parasitic compounds active against…”
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Using topological indices to predict anti-Alzheimer and anti-parasitic GSK-3 inhibitors by multi-target QSAR in silico screening by García, Isela, Fall, Yagamare, Gómez, Generosa

“…Plasmodium falciparum, Leishmania, Trypanosomes, are the causers of diseases such as malaria, leishmaniasis and African trypanosomiasis that nowadays are the…”
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First computational chemistry multi-target model for anti-Alzheimer, anti-parasitic, anti-fungi, and anti-bacterial activity of GSK-3 inhibitors in vitro, in vivo, and in different cellular lines by García, Isela, Fall, Yagamare, Gómez, Generosa, González-Díaz, Humberto

“…In the work described here, we developed the first multi-target quantitative structure–activity relationship (QSAR) model able to predict the results of 42…”
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QSAR & complex network study of the HMGR inhibitors structural diversity by García, Isela, Diop, Yagamare Fall, Gómez, Generosa

“…Efficient drugs such as statins or mevinic acids are inhibitors of the rate-limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methyl-glutaryl coenzyme A…”
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Administration of low doses of the 5-HT1A receptor agonist 8-OH-DPAT attenuates the discriminative signal of amphetamine in the conditioned taste aversion procedure by Sandoval-Sánchez, Alma R., Cedillo Zavaleta, Laura N., Jiménez, Juan C., Ruíz-García, Isela, Miranda, Florencio

“…Several studies have reported that low doses of the 5-HT1A receptor agonist 8-OH-DPAT reduce cocaine-induced locomotor activity. However, it has also been…”
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Review of synthesis, biological assay, and QSAR studies of HMGR inhibitors by García, Isela, Fall, Yagamare, Gómez, Generosa

“…Effective as statin drugs or acids are inhibitors mevinic limiting enzyme in cholesterol biosynthesis, 3-hydroxy- 3-methyl-glutaryl coenzyme…”
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New synthetic strategies to vitamin D analogues by García, Isela, Fall, Yagamare, Gómez, Generosa

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Entropy multi-target QSAR model for prediction of antiviral drug complex networks by Prado-Prado, Francisco J., García, Isela, García-Mera, Xerardo, González-Díaz, Humberto

“…The antiviral QSAR models today have an important limitation. Only they predict the biological activity of drugs against only one viral species. This is…”
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QSAR and complex network study of the chiral HMGR inhibitor structural diversity by García, Isela, Munteanu, Cristian Robert, Fall, Yagamare, Gómez, Generosa, Uriarte, Eugenio, González-Díaz, Humberto

“…Efficient drugs such as statins or mevinic acids are inhibitors of the rate-limiting enzyme of cholesterol biosynthesis, 3-hydroxy-3-methyl-glutaryl coenzyme A…”
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Theoretical study of GSK−3α: neural networks QSAR studies for the design of new inhibitors using 2D descriptors by García, Isela, Fall, Yagamare, García-Mera, Xerardo, Prado-Prado, Francisco

“…Glycogen synthase kinase-3 (GSK-3) targets encompass proteins implicated in AD and neurological disorders. The functions of GSK-3 and its implication in…”
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Synthetic studies toward zoapatanol by García, Isela, Pérez, Manuel, Besada, Pedro, Gómez, Generosa, Fall, Yagamare

“…The oxepane core of zoapatanol was efficiently synthesized from commercially available 1,2,4-butanetriol, and it was shown to be possible to introduce the…”
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Review of QSAR for DNA polymerase inhibitors and new models for heterogeneous series of compounds by García, Isela, Fall, Yagamare, Gómez, Generosa

“…DNA polymerases are essential enzymes for DNA replication, repair and recombination. The high number of possible candidates creates the necessity of…”
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N‐(furan‐2‐ylmethyl)‐N‐methylprop‐2‐yn‐1‐amine (F2MPA): A Potential Cognitive Enhancer with MAO Inhibitor Properties by Di Giovanni, Giuseppe, García, Isela, Colangeli, Roberto, Pierucci, Massimo, Rivadulla, Marcos L., Soriano, Elena, Chioua, Mourad, Della Corte, Laura, Yáñez, Matilde, De Deurwaerdère, Philippe, Fall, Yagamare, Marco‐Contelles, José

“…Summary Background A considerable body of human and animal experimental evidence links monoaminergic systems and cognition. Monoamine oxidase inhibitors…”
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The furan approach to azacyclic compounds by García, Isela, Pérez, Manuel, Gándara, Zoila, Gómez, Generosa, Fall, Yagamare

“…We describe an efficient new approach to the synthesis of azacyclic compounds that extends our recently developed methodology based on the oxidation of a furan…”
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Oregano (Lippia graveolens) essential oil added within pectin edible coatings prevents fungal decay and increases the antioxidant capacity of treated tomatoes by Rodriguez-Garcia, Isela, Cruz-Valenzuela, M Reynaldo, Silva-Espinoza, Brenda A, Gonzalez-Aguilar, Gustavo A, Moctezuma, Edgar, Gutierrez-Pacheco, M Melissa, Tapia-Rodriguez, Melvin R, Ortega-Ramirez, Luis A, Ayala-Zavala, J Fernando

“…BACKGROUND Tomato is a fruit widely consumed due to its flavor and nutritional value; however, it is susceptible to fungi contamination. Oregano essential oil…”
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Potential of Medicinal Plants as Antimicrobial and Antioxidant Agents in Food Industry: A Hypothesis by Ortega‐Ramirez, Luis Alberto, Rodriguez‐Garcia, Isela, Leyva, Juan Manuel, Cruz‐Valenzuela, Manuel Reynaldo, Silva‐Espinoza, Brenda Adriana, Gonzalez‐Aguilar, Gustavo A, Siddiqui, Md Wasim, Ayala‐Zavala, Jesus Fernando

“…Many food preservation strategies can be used for the control of microbial spoilage and oxidation; however, these quality problems are not yet controlled…”
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Myristic Acid Produces Anxiolytic-Like Effects in Wistar Rats in the Elevated Plus Maze by Contreras, Carlos M., Rodríguez-Landa, Juan Francisco, García-Ríos, Rosa Isela, Cueto-Escobedo, Jonathan, Guillen-Ruiz, Gabriel, Bernal-Morales, Blandina

“…A mixture of eight fatty acids (linoleic, palmitic, stearic, myristic, elaidic, lauric, oleic, and palmitoleic acids) at similar concentrations identified in…”
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Oregano essential oil-pectin edible films as anti-quorum sensing and food antimicrobial agents by Alvarez, Maria V, Ortega-Ramirez, Luis A, Gutierrez-Pacheco, M Melissa, Bernal-Mercado, A Thalia, Rodriguez-Garcia, Isela, Gonzalez-Aguilar, Gustavo A, Ponce, Alejandra, Moreira, Maria Del R, Roura, Sara I, Ayala-Zavala, J Fernando

“…Edible films can be used as carriers for antimicrobial compounds to assure food safety and quality; in addition, pathogenesis of food bacteria is related to a…”
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Anxiolytic-Like Actions of Fatty Acids Identified in Human Amniotic Fluid by García-Ríos, Rosa Isela, Contreras, C. M., Rodríguez-Landa, Juan Francisco

“…Eight fatty acids (C12–C18) were previously identified in human amniotic fluid, colostrum, and milk in similar proportions but different amounts. Amniotic…”
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Anxiolytic-like effect of the aqueous extract of Justicia spicigera leaves on female rats: A comparison to diazepam by García-Ríos, Rosa Isela, Mora-Pérez, Armando, González-Torres, Daniel, Carpio-Reyes, Ricardo de Jesús, Soria-Fregozo, Cesar

“…In Mexico, an infusion made from muicle (Justicia spicigera, Mexican honeysuckle) is used to treat menstrual problems and soothe people's “nerves” (i.e.,…”
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