Search Results - "Garcés, Mariana"
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Mitochondrial bioenergetics links inflammation and cardiac contractility in endotoxemia
Published in Basic research in cardiology (01-09-2019)“…There is current awareness about the central role of mitochondrial dysfunction in the development of cardiac dysfunction in systemic inflammatory syndromes,…”
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Inhalable Mannosylated Rifampicin-Curcumin Co-Loaded Nanomicelles with Enhanced In Vitro Antimicrobial Efficacy for an Optimized Pulmonary Tuberculosis Therapy
Published in Pharmaceutics (28-04-2022)“…Among respiratory infections, tuberculosis was the second deadliest infectious disease in 2020 behind COVID-19. Inhalable nanocarriers offer the possibility of…”
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Urban air pollution induces alterations in redox metabolism and mitochondrial dysfunction in mice brain cortex
Published in Archives of biochemistry and biophysics (15-06-2021)“…Previous reports indicate that the central nervous system (CNS) is a target of air pollution, causing tissue damage and functional alterations. Oxidative…”
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Development of a new micellar formulation of carvedilol and curcumin to enhance blood pressure reduction in a spontaneously hypertensive rat model
Published in Naunyn-Schmiedeberg's archives of pharmacology (18-10-2024)“…Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide, requiring innovative therapeutic strategies. This project explores a…”
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Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure
Published in Free radical biology & medicine (01-04-2021)“…Along with the AgNP applications development, the concern about their possible toxicity has increasingly gained attention. As the respiratory system is one of…”
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NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter
Published in Ecotoxicology and environmental safety (01-12-2020)“…Exposure to ambient air particulate matter (PM) is associated with increased cardiorespiratory morbidity and mortality. In this context, alveolar macrophages…”
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Role of transition metals present in air particulate matter on lung oxygen metabolism
Published in The international journal of biochemistry & cell biology (01-12-2016)“…Several epidemiological studies have shown a positive correlation between daily increases in airborne particulate matter (PM) concentration and the occurrence…”
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Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice
Published in Toxicology (Amsterdam) (01-12-2021)“…[Display omitted] •Ni-NP alters lung O2 metabolism increasing ROS production by mitochondria and NOX.•Ni-NP-increased ROS production leads to lung oxidative…”
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Selective TNF-α targeting with infliximab attenuates impaired oxygen metabolism and contractile function induced by an acute exposure to air particulate matter
Published in American journal of physiology. Heart and circulatory physiology (15-11-2015)“…Inflammation plays a central role in the onset and progression of cardiovascular diseases associated with the exposure to air pollution particulate matter…”
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Airborne particulate matter exposure impairs lung redox metabolism involved in tissue damage repair mechanisms
Published in Free radical biology & medicine (01-03-2023)Get full text
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Cardioprotective effect of remote ischemic preconditioning through attenuation of oxidative stress and inflammatory response
Published in Free radical biology & medicine (01-03-2023)Get full text
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First evidence of redox damage by indoor pollution in lung tissue by the use of 2D and 3D models
Published in Free radical biology & medicine (01-06-2024)Get full text
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Myocardial triggers involved in activation of remote ischaemic preconditioning
Published in Experimental physiology (01-06-2016)“…New Findings What is the central question of this study? Ischaemia–reperfusion of peripheral tissues protects the heart from subsequent myocardial…”
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Airborne particulate matter exposure impairs lung redox metabolism involved in tissue damage repair mechanisms
Published in Free radical biology & medicine (20-05-2023)Get full text
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Urban air exposure exacerbates the oxinflammatory response worsening the recovery after an acute lung injury
Published in Free radical biology & medicine (01-06-2024)Get full text
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Evaluation of the air pollution-induced adverse effects reversibility on olfactory bulb
Published in Free radical biology & medicine (01-06-2024)Get full text
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A chronic exposure to urban polluted air hampers cardiac mitochondrial dynamics in mice
Published in Free radical biology & medicine (01-12-2021)Get full text
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