Search Results - "Garber, D W"

Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide by Datta, G, Chaddha, M, Hama, S, Navab, M, Fogelman, A M, Garber, D W, Mishra, V K, Epand, R M, Epand, R F, Lund-Katz, S, Phillips, M C, Segrest, J P, Anantharamaiah, G M

“…We have recently shown that a class A amphipathic peptide 5F with increased amphipathicity protected mice from diet-induced atherosclerosis (Garber et al. J…”
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A new synthetic class A amphipathic peptide analogue protects mice from diet-induced atherosclerosis by Garber, D W, Datta, G, Chaddha, M, Palgunachari, M N, Hama, S Y, Navab, M, Fogelman, A M, Segrest, J P, Anantharamaiah, G M

“…Several synthetic class A peptide analogues have been shown to mimic many of the properties of human apo A-I in vitro. A new peptide…”
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Quantification of cholesterol in all lipoprotein classes by the VAP-II method by Kulkarni, K.R, Garber, D.W, Marcovina, S.M, Segrest, J.P

“…We have developed a high resolution microvolume Vertical Auto Profile (VAP) method for the simultaneous measurement of cholesterol in all lipoprotein classes,…”
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ApoB-100 has a pentapartite structure composed of three amphipathic α-helical domains alternating with two amphipathic β-strand domains : detection by the computer program LOCATE by SEGREST, J. P, JONES, M. K, MISHRA, V. K, ANANTHARAMAIAH, G. M, GARBER, D. W

“…Due to the great length of apolipoprotein (apo) B-100, the localization of lipid-associating domains in this protein has been difficult. To address this…”
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The effects of low-density lipoprotein and high-density lipoprotein on blood viscosity correlate with their association with risk of atherosclerosis in humans by Sloop, G D, Garber, D W

“…1. Increased blood or plasma viscosity has been observed in almost all conditions associated with accelerated atherosclerosis. Cognizant of the enlarging body…”
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Cationic domain 141-150 of apoE covalently linked to a class A amphipathic helix enhances atherogenic lipoprotein metabolism in vitro and in vivo by Datta, G, Garber, D W, Chung, B H, Chaddha, M, Dashti, N, Bradley, W A, Gianturco, S H, Anantharamaiah, G M

“…We previously showed 1 that a peptide, Ac-hE18A-NH(2), in which the arginine-rich heparin-binding domain of apolipoprotein E (apoE) [residues 141;-150]…”
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Apolipoprotein A-I Mimetic Peptides by Navab, Mohamad, Anantharamaiah, G M, Reddy, Srinivasa T, Hama, Susan, Hough, Greg, Grijalva, Victor R, Yu, Nicholas, Ansell, Benjamin J, Datta, Geeta, Garber, David W, Fogelman, Alan M

“…Despite identical amino acid composition, differences in class A amphipathic helical peptides caused by differences in the order of amino acids on the…”
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Identification and cholesterol quantification of low density lipoprotein subclasses in young adults by VAP-II methodology by Kulkarni, K.R. (University of Alabama at Birmingham, Birmingham, AL.), Garber, D.W, Jones, M.K, Segrest, J.P

“…Low density lipoprotein (LDL) particles are heterogeneous in size, density, and chemical composition; small, dense LDL may be more atherogenic than large,…”
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D-4F and Statins Synergize to Render HDL Antiinflammatory in Mice and Monkeys and Cause Lesion Regression in Old Apolipoprotein E–Null Mice by Navab, Mohamad, Anantharamaiah, G M, Hama, Susan, Hough, Greg, Reddy, Srinivasa T, Frank, Joy S, Garber, David W, Handattu, Shaila, Fogelman, Alan M

“…OBJECTIVES—We tested for synergy between pravastatin and D-4F by administering oral doses of each in combination that were predetermined to be ineffective when…”
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Quantification of HDL2 and HDL3 cholesterol by the Vertical Auto Profile-II (VAP-II) methodology by Kulkarni, K R, Marcovina, S M, Krauss, R M, Garber, D W, Glasscock, A M, Segrest, J P

“…Of the several existing methods for quantification of major subspecies of high density lipoprotein (HDL), HDL2 and HDL3, the methods based upon double…”
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An Oral ApoJ Peptide Renders HDL Antiinflammatory in Mice and Monkeys and Dramatically Reduces Atherosclerosis in Apolipoprotein E–Null Mice by Navab, Mohamad, Anantharamaiah, G M, Reddy, Srinivasa T, Van Lenten, Brian J, Wagner, Alan C, Hama, Susan, Bachini, Greg Hough Eugene, Garber, David W, Mishra, Vinod K, Palgunachari, Mayakonda N, Fogelman, Alan M

“…OBJECTIVE—To determine the properties of a peptide synthesized from D-amino acids corresponding to residues 113 to 122 in apolipoprotein (apo) J. METHODS AND…”
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A Prospective, Randomized Trial of Phenytoin in Nonepileptic Subjects With Reduced HDL Cholesterol by Miller, Michael, Burgan, Rachel G, Osterlund, Laura, Segrest, Jere P, Garber, David W

“…Observational studies have demonstrated a positive association between phenytoin use and HDL cholesterol (HDL-C). Our goal was to determine whether phenytoin…”
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Catabolism of very low density lipoproteins in experimental nephrosis by GARBER, D. W, GOTTLIEB, B. A, MARSH, J. B, SPARKS, C. E

“…The effects of experimental nephrosis in rats, produced by puromycin aminonucleoside, include an elevation of plasma levels of all lipoprotein density classes…”
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Cardiac function and myosin ATPase in diabetic rats treated with insulin, T3, and T4 by Garber, D W, Everett, A W, Neely, J R

“…The effects of insulin, T4, and T3 treatment on cardiac function, myosin ATPase activity, and myosin isozyme distribution were studied in alloxan diabetic…”
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Decreased myocardial function and myosin ATPase in hearts from diabetic rats by Garber, D W, Neely, J R

“…The effect of diabetes on cardiac function was determined in isolated rat hearts. Diabetes was induced by injection of alloxan (doses ranged from 37.5 to 60…”
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Thyroid function and other clinical chemistry parameters in subjects eating iodine-enriched eggs by Garber, D W, Henkin, Y, Osterlund, L C, Woolley, T W, Segrest, J P

“…Iodine-enriched (IE) eggs are produced by chickens fed a diet containing kelp. These eggs, which contain an average of 711 micrograms iodine/egg, have been…”
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A sensitive and convenient method for lipoprotein profile analysis of individual mouse plasma samples by Garber, D W, Kulkarni, K R, Anantharamaiah, G M

“…A simple and convenient method to determine plasma cholesterol profiles in individual mouse plasma samples is not presently available. With commonly used…”
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The Receptor Binding Domain of Apolipoprotein E, Linked to a Model Class A Amphipathic Helix, Enhances Internalization and Degradation of LDL by Fibroblasts by Datta, Geeta, Chaddha, Manjula, Garber, David W, Chung, Byung Hong, Tytler, Ewan M, Dashti, Nassrin, Bradley, William A, Gianturco, Sandra H, Anantharamaiah, G. M

“…Human apolipoprotein E (apo E) consists of two distinct domains, the lipid-associating domain (residues 192−299) and the globular domain (residues 1−191) which…”
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Analysis of cholesterol in all lipoprotein classes by single vertical ultracentrifugation of fingerstick blood and controlled-dispersion flow analysis by Kulkarni, K R, Garber, D W, Schmidt, C F, Marcovina, S M, Ho, M H, Wilhite, B J, Beaudrie, K R, Segrest, J P

“…This new, highly sensitive analytical system, based on controlled dispersion of the flowing sample, gives a rapid, continuous, and direct analysis for…”
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Toward the design of peptide mimics of antiatherogenic apolipoproteins A-I and E by Anantharamaiah, G. M., Datta, G., Garber, D. W.

“…Two major markers for atherosclerosis are increased plasma cholesterol levels and low levels of high density lipoproteins (HDL). Human apolipoprotein (apo)…”
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