Search Results - "Garbacz, Marta"

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication by Zhou, Zhi-Xiong, Lujan, Scott A., Burkholder, Adam B., Garbacz, Marta A., Kunkel, Thomas A.

“…Most current evidence indicates that DNA polymerases ε and δ, respectively, perform the bulk of leading and lagging strand replication of the eukaryotic…”
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Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency by Lujan, Scott A, Garbacz, Marta A, Liberti, Sascha E, Burkholder, Adam B, Kunkel, Thomas A

“…Abstract The endonuclease activity of Pms1 directs mismatch repair by generating a nick in the newly replicated DNA strand. Inactivating Pms2, the human…”
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Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae by Garbacz, Marta A., Lujan, Scott A., Burkholder, Adam B., Cox, Phillip B., Wu, Qiuqin, Zhou, Zhi-Xiong, Haber, James E., Kunkel, Thomas A.

“…To investigate nuclear DNA replication enzymology in vivo, we have studied Saccharomyces cerevisiae strains containing a pol2-16 mutation that inactivates the…”
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The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity by Garbacz, Marta A, Cox, Phillip B, Sharma, Sushma, Lujan, Scott A, Chabes, Andrei, Kunkel, Thomas A

“…Abstract The four B-family DNA polymerases α, δ, ϵ and ζ cooperate to accurately replicate the eukaryotic nuclear genome. Here, we report that a Saccharomyces…”
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Opportunities for new studies of nuclear DNA replication enzymology in budding yeast by Garbacz, Marta A., Lujan, Scott A., Kunkel, Thomas A.

“…Three major eukaryotic DNA polymerases, Polymerases α, δ, and ε (Pols α, δ, and ε), perform the fundamental process of DNA synthesis at the replication fork…”
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Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex by Garbacz, Marta, Araki, Hiroyuki, Flis, Krzysztof, Bebenek, Anna, Zawada, Anna E., Jonczyk, Piotr, Makiela-Dzbenska, Karolina, Fijalkowska, Iwona J.

“…•The dpb2-100 allele encodes the mutant form of Dpb2p, the noncatalytic subunit of Pol ɛ.•It does not change the biochemical properties of DNA Pol ɛ…”
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Defect of Dpb2p, a noncatalytic subunit of DNA polymerase ɛ, promotes error prone replication of undamaged chromosomal DNA in Saccharomyces cerevisiae by Kraszewska, Joanna, Garbacz, Marta, Jonczyk, Piotr, Fijalkowska, Iwona J, Jaszczur, Malgorzata

“…The Saccharomyces cerevisiae DNA polymerase epsilon holoenzyme (Pol ɛ HE) is composed of four subunits: Pol2p, Dpb2p, Dpb3p and Dpb4p. The biological functions…”
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