Search Results - "Garb, Jessica E"
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Blueprint for a high-performance biomaterial: full-length spider dragline silk genes
Published in PloS one (13-06-2007)“…Spider dragline (major ampullate) silk outperforms virtually all other natural and manmade materials in terms of tensile strength and toughness. For this…”
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Recruitment and diversification of an ecdysozoan family of neuropeptide hormones for black widow spider venom expression
Published in Gene (25-02-2014)“…Venoms have attracted enormous attention because of their potent physiological effects and dynamic evolution, including the convergent recruitment of…”
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Spider phylosymbiosis: divergence of widow spider species and their tissues' microbiomes
Published in BMC evolutionary biology (18-08-2020)“…Microbiomes can have profound impacts on host biology and evolution, but to date, remain vastly understudied in spiders despite their unique and diverse…”
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Untangling spider silk evolution with spidroin terminal domains
Published in BMC evolutionary biology (09-08-2010)“…Spidroins are a unique family of large, structural proteins that make up the bulk of spider silk fibers. Due to the highly variable nature of their repetitive…”
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Correlation between protein secondary structure and mechanical performance for the ultra-tough dragline silk of Darwin's bark spider
Published in Journal of the Royal Society interface (01-06-2021)“…The spider major ampullate (MA) silk exhibits high tensile strength and extensibility and is typically a blend of MaSp1 and MaSp2 proteins with the latter…”
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Evolutionary shifts in gene expression decoupled from gene duplication across functionally distinct spider silk glands
Published in Scientific reports (21-08-2017)“…Spider silk synthesis is an emerging model for the evolution of tissue-specific gene expression and the role of gene duplication in functional novelty, but its…”
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Early events in the evolution of spider silk genes
Published in PloS one (22-06-2012)“…Silk spinning is essential to spider ecology and has had a key role in the expansive diversification of spiders. Silk is composed primarily of proteins called…”
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Multi-tissue transcriptomics of the black widow spider reveals expansions, co-options, and functional processes of the silk gland gene toolkit
Published in BMC genomics (11-06-2014)“…Spiders (Order Araneae) are essential predators in every terrestrial ecosystem largely because they have evolved potent arsenals of silk and venom. Spider…”
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Expanding Canonical Spider Silk Properties through a DNA Combinatorial Approach
Published in Materials (14-08-2020)“…The properties of native spider silk vary within and across species due to the presence of different genes containing conserved repetitive core domains…”
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The transcriptome of Darwin’s bark spider silk glands predicts proteins contributing to dragline silk toughness
Published in Communications biology (25-07-2019)“…Darwin’s bark spider ( Caerostris darwini ) produces giant orb webs from dragline silk that can be twice as tough as other silks, making it the toughest…”
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Effects of Gene Duplication, Positive Selection, and Shifts in Gene Expression on the Evolution of the Venom Gland Transcriptome in Widow Spiders
Published in Genome biology and evolution (01-01-2016)“…Gene duplication and positive selection can be important determinants of the evolution of venom, a protein-rich secretion used in prey capture and defense. In…”
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The black widow spider genus Latrodectus (Araneae: Theridiidae): phylogeny, biogeography, and invasion history
Published in Molecular phylogenetics and evolution (01-06-2004)“…The spider genus Latrodectus includes the widely known black widows, notorious because of the extreme potency of their neurotoxic venom. The genus has a…”
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Alternative Transcription at Venom Genes and Its Role as a Complementary Mechanism for the Generation of Venom Complexity in the Common House Spider
Published in Frontiers in ecology and evolution (01-04-2019)“…The complex composition of venom, a proteinaceous secretion used by diverse animal groups for predation or defense, is typically viewed as being driven by gene…”
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Modular evolution of egg case silk genes across orb-weaving spider superfamilies
Published in Proceedings of the National Academy of Sciences - PNAS (09-08-2005)“…Spider silk proteins (fibroins) are renowned for their extraordinary mechanical properties and biomimetic potential. Despite extensive evolutionary,…”
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Silk Genes Support the Single Origin of Orb Webs
Published in Science (American Association for the Advancement of Science) (23-06-2006)“…The orb web is a spectacular evolutionary innovation that enables spiders to catch flying prey. This elegant, geometric structure is woven with silk fibers…”
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Island hopping across the central Pacific: mitochondrial DNA detects sequential colonization of the Austral Islands by crab spiders (Araneae: Thomisidae)
Published in Journal of biogeography (01-02-2006)“…Aim Phylogenetic studies concerning island biogeography have been concentrated in a fraction of the numerous hot-spot archipelagos contained within the Pacific…”
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Molecular evolution of α-latrotoxin, the exceptionally potent vertebrate neurotoxin in black widow spider venom
Published in Molecular biology and evolution (01-05-2013)“…Black widow spiders (members of the genus Latrodectus) are widely feared because of their potent neurotoxic venom. α-Latrotoxin is the vertebrate-specific…”
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Stichodactyla helianthus' de novo transcriptome assembly: Discovery of a new actinoporin isoform
Published in Toxicon (Oxford) (01-08-2018)“…Transcriptomic profiling of venom producing tissues from different animals is an effective approach for discovering new toxins useful in biotechnological and…”
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Ancient properties of spider silks revealed by the complete gene sequence of the prey-wrapping silk protein (AcSp1)
Published in Molecular biology and evolution (01-03-2013)“…Spider silk fibers have impressive mechanical properties and are primarily composed of highly repetitive structural proteins (termed spidroins) encoded by a…”
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Extraction of venom and venom gland microdissections from spiders for proteomic and transcriptomic analyses
Published in Journal of visualized experiments (03-11-2014)“…Venoms are chemically complex secretions typically comprising numerous proteins and peptides with varied physiological activities. Functional characterization…”
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