Search Results - "Garay Pérez, Hilda"

d‐Amino acid substitutions and dimerization increase the biological activity and stability of an IL‐15 antagonist peptide by Rodríguez‐Álvarez, Yunier, Cabrales‐Rico, Ania, Diago‐Abreu, David, Correa‐Arguelles, Elianys, Reyes‐Acosta, Osvaldo, Puente‐Pérez, Pedro, Pichardo‐Díaz, Dagmara, Urquiza‐Noa, Dioslaida, Hernández‐Santana, Amalia, Garay‐Pérez, Hilda E.

“…Interleukin (IL)‐15 plays an important role in several inflammatory diseases. We have previously identified an IL‐15 antagonist called P8 peptide, which binds…”
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Influence of Humoral Response Against GnRH, Generated by Immunization with a Therapeutic Vaccine Candidate on the Evolution of Patients with Castration-Sensitive Prostate Adenocarcinoma by Campal-Espinosa, Ana Cristina, Junco-Barranco, Jesús Arturo, Fuentes-Aguilar, Franklin, Calzada-Aguilera, Lesvia, Rivacoba-Betancourt, Annia, Rodríguez-Bueno, Ranfis Humberto, Bover-Campal, Ana Claudia, Bover-Fuentes, Eddy Emilio, González, Lourdes, de Quesada, Lourdes, Alvarez, Allelin, Garay-Pérez, Hilda Elisa

“…Background and aims A gonadotropin-releasing hormone (GnRH)-based therapeutic vaccine candidate against hormone-sensitive prostate cancer has demonstrated its…”
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Very Small Size Proteoliposomes (VSSP) and Montanide combination enhance the humoral immuno response in a GnRH based vaccine directed to prostate cancer by Aguilar, Franklin Fuentes, Barranco, Jesús Junco, Fuentes, Eddy Bover, Aguilera, Lesvia Calzada, Sáez, Yovisleydis Lopez, Santana, María Dolores Castro, Vázquez, Eulogio Pimentel, Baker, Roberto Basulto, Acosta, Osvaldo Reyes, Pérez, Hilda Garay, Nieto, Gerardo Guillén

“…Highlights ► Increasing antibody against GnRH will decrease testosterone levels. ► VSSP increase the immune humoral response.► Peptide administration without…”
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Insights into the Adsorption Mechanisms of the Antimicrobial Peptide CIDEM-501 on Membrane Models by Alpízar-Pedraza, Daniel, Roque-Diaz, Yessica, Garay-Pérez, Hilda, Rosenau, Frank, Ständker, Ludger, Montero-Alejo, Vivian

“…CIDEM-501 is a hybrid antimicrobial peptide rationally designed based on the structure of panusin and panulirin template peptides. The new peptide exhibits…”
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In vitro and in vivo characterization of an interleukin-15 antagonist peptide by metabolic stability, 99m Tc-labeling, and biological activity assays by Rodríguez-Álvarez, Yunier, Cabrales-Rico, Ania, Perera-Pintado, Alejandro, Prats-Capote, Anais, Garay-Pérez, Hilda E, Reyes-Acosta, Osvaldo, Pérez-García, Erik, Chico-Capote, Araceli, Santos-Savio, Alicia

“…Interleukin (IL)-15 is an inflammatory cytokine that constitutes a validated therapeutic target in some immunopathologies, including rheumatoid arthritis (RA)…”
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The influence of different peptide combinations to increase the immunogenicity of the Gonadotrophin Releasing Hormone Vaccine for prostate cancer treatment by Aguilar, Franklin Fuentes, Barranco, Jesús Junco, Aguilera, Lesvia Calzada, Fuentes, Eddy Bover, Serradelo Leal, Jose André, López, Eduardo Hernández, Vázquez, Eulogio Pimentel, Baker, Roberto Basulto, Acosta, Osvaldo Reyes, Pérez, Hilda Garay, Nieto, Gerardo Guillén

“…Therapeutic vaccines, specifically the Gonadotrophin Releasing Hormone (GnRH) vaccine, are considered an additional therapeutic option for advanced stage…”
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In vitro and in vivo characterization of an interleukin‐15 antagonist peptide by metabolic stability, 99mTc‐labeling, and biological activity assays by Rodríguez‐Álvarez, Yunier, Cabrales‐Rico, Ania, Perera‐Pintado, Alejandro, Prats‐Capote, Anais, Garay‐Pérez, Hilda E., Reyes‐Acosta, Osvaldo, Pérez‐García, Erik, Chico‐Capote, Araceli, Santos‐Savio, Alicia

“…Interleukin (IL)–15 is an inflammatory cytokine that constitutes a validated therapeutic target in some immunopathologies, including rheumatoid arthritis (RA)…”
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Enhancement of the inhibitory effect of an IL-15 antagonist peptide by alanine scanning by Savio, Alicia Santos, Acosta, Osvaldo Reyes, Pérez, Haydee Gerónimo, Álvarez, Yunier Rodríguez, Chico, Araceli, Pérez, Hilda Garay, Ojeda, Miriam Ojeda, Aguero, Celia Aurora Arrieta, Estévez, Miguel, Nieto, Gerardo Guillen

“…IL‐15 is a proinflammatory cytokine that acts early in the inflammatory response and has been associated with several autoimmune diseases including rheumatoid…”
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Formulation matters! A spectroscopic and molecular dynamics investigation on the peptide CIGB552 as itself and in its therapeutical formulation by Savioli, Marco, Antonelli, Lorenzo, Bocchinfuso, Gianfranco, Cavalieri, Francesca, Cimino, Rita, Gatto, Emanuela, Placidi, Ernesto, Fernandez Masso, Julio Raul, Garay Perez, Hilda, Santana, Hector, Guerra‐Vallespi, Maribel, Venanzi, Mariano

“…Synthetic therapeutic peptides (STP) are intensively studied as new‐generation drugs, characterized by high purity, biocompatibility, selectivity and…”
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Alginate Microsponges as a Scaffold for Delivery of a Therapeutic Peptide against Rheumatoid Arthritis by Ariaudo, Daniela, Cavalieri, Francesca, Rinaldi, Antonio, Aguilera, Ana, Lopez, Matilde, Perez, Hilda Garay, Felipe, Ariel, del Carmen Dominguez, Maria, Ruiz, Odalys, Martinez, Gillian, Venanzi, Mariano

“…The quest for biocompatible drug-delivery devices that could be able to open new administration routes is at the frontier of biomedical research. In this…”
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Diagnostic Value of Anti-Fibrinogen Citrullinated Peptide in Rheumatoid Arthritis by Martínez Téllez, Goitybell, Torres Rives, Bárbara, Gómez Morejón, Jorge Alexis, Pérez Garay, Hilda, Rodríguez, Antonio Melchor, Portal Miranda, Jose Ángel

“…OBJECTIVETo determinate the diagnostic value of an antibody against a citrullinated fibrinogen peptide in Cuban patients with rheumatoid arthritis, using an…”
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Aggregation properties of a therapeutic peptide for rheumatoid arthritis: A spectroscopic and molecular dynamics study by Cimino, Rita, Savioli, Marco, Carrante, Noemi Ferrante, Placidi, Ernesto, Garay-Perez, Hilda, López-Abad, Matilde, Lasa, Alexis Musacchio, Domínguez-Horta, Maria Del Carmen, Gatto, Emanuela, Cavalieri, Francesca, Bocchinfuso, Gianfranco, Venanzi, Mariano

“…•Aggregation of a therapeutic peptide against rheumatoid arthritis is characterized by a multistep process strongly dependent on peptide concentration.•The…”
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Diagnostic value of anti-fibrinogen citrullinated peptide in rheumatoid arthritis by Martínez Téllez, Goitybell, Torres Rives, Bárbara, Gómez Morejón, Jorge Alexis, Pérez Garay, Hilda, Rodríguez, Antonio Melchor, Portal Miranda, Jose Ángel

“…To determinate the diagnostic value of an antibody against a citrullinated fibrinogen peptide in Cuban patients with rheumatoid arthritis, using an enzyme…”
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Valor diagnóstico de anticuerpos antipéptido citrulinado del fibrinógeno en la artritis reumatoide by Martínez Téllez, Goitybell, Torres Rives, Bárbara, Gómez Morejón, Jorge Alexis, Pérez Garay, Hilda, Rodríguez, Antonio Melchor, Portal Miranda, Jose Ángel

“…Resumen Objetivo Determinar el valor diagnóstico de los anticuerpos contra un péptido del fibrinógeno citrulinado, en pacientes cubanos con artritis reumatoide…”
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Effects of Two GnRH-based Recombinant Vaccine Candidates on Pig Fertility by Roberto Basulto Baker, Gerardo Guillén Nieto, Lesvia Calzada Aguilera, Jesús Junco Barranco, Nelson Izquierdo Pérez, Osvaldo Reyes Acosta, Hilda Garay Pérez, Ricardo Bringas Pérez, Eulogio Pimentel Vázquez, José A. Bertot, Rafael Avilés, María Dolores Castro Santana, Eddy Bover Fuentes, Franklin Fuentes Aguilar

“…This paper describes for the first time the generation of the K88ab-GnRH hybrid fimbria, the fusion of N. meningitidis P64k protein (P64k-GnRH), and its…”
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Efectos sobre la fertilidad del cerdo de dos candidatos vacunales recombinantes basados en la GnRH by Roberto Basulto Baker, Gerardo Guillén Nieto, Lesvia Calzada Aguilera, Jesús Junco Barranco, Nelson Izquierdo Pérez, Osvaldo Reyes Acosta, Hilda Garay Pérez, Ricardo Bringas Pérez, Eulogio Pimentel Vázquez, José A. Bertot, Rafael Avilés, María Dolores Castro Santana, Eddy Bover Fuentes, Franklin Fuentes Aguilar

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Efectos sobre la fertilidad del cerdo de dos candidatos vacunales recombinantes basados en la GnRH by Basulto Baker, Roberto, Guillén Nieto, Gerardo, Calzada Aguilera, Lesvia, Junco Barranco, Jesús, Izquierdo Pérez, Nelson, Reyes Acosta, Osvaldo, Garay Pérez, Hilda, Bringas Pérez, Ricardo, Pimentel Vázquez, Eulogio, Bertot, José A, Avilés, Rafael, Castro Santana, María Dolores, Bover Fuentes, Eddy, Fuentes Aguilar, Franklin

“…En este trabajo se describe, por primera vez, la obtención de la fimbria híbrida K88ab-GnRH, la fusión de la GnRH a la proteína P64k de N. meningitidis…”
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Application of a colorimetric CTLL-2 cell proliferation assay for the evaluation of IL-15 antagonists by Yunier Rodríguez-Álvarez, Haydee Gerónimo-Pérez, Hilda Garay-Pérez, Jorge Castro-Velazco, Gerardo García-Illera, Alicia Santos-Savio

“…Dysregulated expression of Interleukin (IL)-15 has been associated to several autoimmune and inflammatory diseases. In this sense, some agents that inhibit…”
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Effect of a GnRH vaccine formulation on testosterone concentrations and reproduction in adult male rats by Franklin Fuentes, Jesús Junco, Lesvia Calzada, Yovisleydis Lopez, Eulogio Pimentel, Roberto Basulto Baker, Osvaldo Reyes Acosta, Hilda E Garay-Pérez, Gerardo Guillén-Nieto

“…In this study is described the effect of different doses of the gonadotropin releasing hormone (GnRH) mimetic peptide GnRHm1-TT, administered in three…”
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Rational design of an antitumor peptide based on the 32-51 region of the Limulus anti-LPS factor protein obtained from a chemical library by Maribel Guerra-Vallespi, Julio R Fernández-Massó, Osvaldo Reyes-Acosta, Hilda Garay-Pérez, Isis Torrens-Madrazo, Milaid Granadillo-Rodríguez, Brizaida Oliva-Argüelles, Isbel García, Isabel Guillén-Pérez, Daniel Palenzuela-Gardón, Dania Vázquez-Blomquist, Viviana Falcón-Cama, Osmany Mendoza-Fuentes, Orlando Borras-Hidalgo, Lidia I Novoa-Pérez, Mariela Vázquez-Castillo

“…In previous work, we identified the peptide comprising amino acids 32-51 on the antimicrobial protein limulus anti-LPS factor (LALF) from Limulus poliphemus,…”
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