Search Results - "Garamszegi, Susanna P"

Altered Dopamine Synaptic Markers in Postmortem Brain of Obese Subjects by Wu, Chun, Garamszegi, Susanna P, Xie, Xiaobin, Mash, Deborah C

“…Dopaminergic signaling in the reward pathway in the brain has been shown to play an important role in food intake and the development of obesity. Obese rats…”
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TDP-43 and Alzheimer's Disease Pathology in the Brain of a Harbor Porpoise Exposed to the Cyanobacterial Toxin BMAA by Garamszegi, Susanna P, Brzostowicki, Daniel J, Coyne, Thomas M, Vontell, Regina T, Davis, David A

“…Cetaceans are well-regarded as sentinels for toxin exposure. Emerging studies suggest that cetaceans can also develop neuropathological changes associated with…”
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Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder by Ribeiro, Efrain A., Scarpa, Joseph R., Garamszegi, Susanna P., Kasarskis, Andrew, Mash, Deborah C., Nestler, Eric J.

“…Metabolic and functional alterations of neurons in the dorsolateral prefrontal cortex (dlPFC) are thought to contribute to impulsivity, which is a hallmark of…”
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BMAA, Methylmercury, and Mechanisms of Neurodegeneration in Dolphins: A Natural Model of Toxin Exposure by Davis, David A, Garamszegi, Susanna P, Banack, Sandra Anne, Dooley, Patrick D, Coyne, Thomas M, McLean, Dylan W, Rotstein, David S, Mash, Deborah C, Cox, Paul Alan

“…Dolphins are well-regarded sentinels for toxin exposure and can bioaccumulate a cyanotoxin called β- -methylamino-l-alanine (BMAA) that has been linked to…”
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Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer's disease by Dallmeier, Julian D, Gober, Ryan, Vontell, Regina T, Barreda, Ayled, Dorfsman, Daniel A, Davis, David A, Sun, Xiaoyan, Brzostowicki, Daniel, Bennett, Illiana, Garamszegi, Susanna P, Wander, Connor M, Cohen, Todd, Scott, William K

“…Severity and distribution of aggregated tau and neurofibrillary tangles (NFT) are strongly correlated with the clinical presentation of Alzheimer's disease…”
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RNA sequencing in post‐mortem human brains of neuropsychiatric disorders by Wu, Chun, Bendriem, Raphael M., Garamszegi, Susanna P., Song, Lei, Lee, Chun‐Ting

“…RNA sequencing (RNA‐Seq), a revolutionary tool for transcriptome profiling, is becoming increasingly important for neuroscientists in studying the…”
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Detection of β-N-methylamino-l-alanine in postmortem olfactory bulbs of Alzheimer’s disease patients using UHPLC-MS/MS: An autopsy case-series study by Garamszegi, Susanna P., Banack, Sandra Anne, Duque, Linda L., Metcalf, James S., Stommel, Elijah W., Cox, Paul Alan, Davis, David A.

“…Cyanobacterial blooms produce toxins that may become aerosolized, increasing health risks through inhalation exposures. Health related effects on the lower…”
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Matrix metalloproteinase 1: role in sarcoma biology by Jawad, Muhammad Umar, Garamszegi, Nandor, Garamszegi, Susanna P, Correa-Medina, Mayrin, Diez, Juan A, Wen, Rong, Scully, Sean P

“…In carcinomas stromal cells participate in cancer progression by producing proteases such as MMPs. The expression MMP1 is a prognostic factor in human…”
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Extracellular Matrix-Induced Gene Expression in Human Breast Cancer Cells by Garamszegi, Nandor, Garamszegi, Susanna P, Shehadeh, Lina A, Scully, Sean P

“…Extracellular matrix (ECM) molecules modify gene expression through attachment-dependent (focal adhesion-related) integrin receptor signaling. It was…”
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Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions by Gober, Ryan, Ardalan, Maryam, Shiadeh, Seyedeh Marziyeh Jabbari, Duque, Linda, Garamszegi, Susanna P., Ascona, Maureen, Barreda, Ayled, Sun, Xiaoyan, Mallard, Carina, Vontell, Regina T.

“…Schizophrenia (SCZ) is a psychiatric disorder that can include symptoms of disorganized speech and thoughts with uncertain underlying mechanisms possibly…”
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l-Serine Reduces Spinal Cord Pathology in a Vervet Model of Preclinical ALS/MND by Davis, David A, Cox, Paul Alan, Banack, Sandra Anne, Lecusay, Patricia D, Garamszegi, Susanna P, Hagan, Matthew J, Powell, James T, Metcalf, James S, Palmour, Roberta M, Beierschmitt, Amy, Bradley, Walter G, Mash, Deborah C

“…Abstract The early neuropathological features of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND) are protein aggregates in motor neurons and…”
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The Myosin Cardiac Loop Participates Functionally in the Actomyosin Interaction by Ajtai, Katalin, Garamszegi, Susanna P., Watanabe, Shinya, Ikebe, Mitsuo, Burghardt, Thomas P.

“…The motor protein myosin in association with actin transduces chemical free energy in ATP into work in the form of actin translation against an opposing force…”
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Low Dopamine D2 Receptor Expression Drives Gene Networks Related to GABA, cAMP, Growth and Neuroinflammation in Striatal Indirect Pathway Neurons by Guerri, Lucia, Dobbs, Lauren K., da Silva e Silva, Daniel A., Meyers, Allen, Ge, Aaron, Lecaj, Lea, Djakuduel, Caroline, Islek, Damien, Hipolito, Dionisio, Martinez, Abdiel Badillo, Shen, Pei-Hong, Marietta, Cheryl A., Garamszegi, Susanna P., Capobianco, Enrico, Jiang, Zhijie, Schwandt, Melanie, Mash, Deborah C., Alvarez, Veronica A., Goldman, David

“…A salient effect of addictive drugs is to hijack the dopamine reward system, an evolutionarily conserved driver of goal-directed behavior and learning. Reduced…”
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Matrix metalloproteinase‐1 contribution to sarcoma cell invasion by Garamszegi, Nandor, Garamszegi, Susanna P., Scully, Sean P.

“…Matrix metalloproteinase‐1 (MMP‐1) activity has been linked to numerous disease processes from arthritis to ulcer. Its proteolytic activity has been implicated…”
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Probes Bound to Myosin Cys-707 Rotate during Length Transients in Contraction by Burghardt, Thomas P., Garamszegi, Susanna P., Ajtai, Katalin

“…It is widely conjectured that muscle shortens because portions of myosin molecules (the ``cross-bridges'') impel the actin filament to which they transiently…”
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Molecular mechanism of tenascin-C action on matrix metalloproteinase-1 invasive potential by Galoian, Karine A, Garamszegi, Nandor, Garamszegi, Susanna P, Scully, Sean P

“…The aim of the current study was to confirm that tenascin-C large splice variant (TNC320) stimulates matrix metalloproteinase-1 (MMP-1) expression and to…”
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Structural Characterization of β-Cardiac Myosin Subfragment 1 in Solution by Ajtai, Katalin, Garamszegi, Susanna P, Park, Sungjo, Velazquez Dones, Adolfo L, Burghardt, Thomas P

“…β-cardiac myosin subfragment 1 (βS1) tertiary structure and dynamics were characterized with proteolytic digestion, nucleotide analogue trapping kinetics, and…”
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Tertiary Structural Changes in the Cleft Containing the ATP Sensitive Tryptophan and Reactive Thiol Are Consistent with Pivoting of the Myosin Heavy Chain at Gly699 by Burghardt, Thomas P, Garamszegi, Susanna P, Park, Sungjo, Ajtai, Katalin

“…The conformation of myosin subfragment 1 (S1) in the vicinity of the ATP sensitive tryptophan (Trp510) and the highly reactive thiol (SH1), both residing in…”
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