Search Results - "Garamszegi, Nandor"

Cell-Type-Specific Activation of PAK2 by Transforming Growth Factor β Independent of Smad2 and Smad3 by Wilkes, Mark C., Murphy, Stephen J., Garamszegi, Nandor, Leof, Edward B.

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Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway by Penheiter, Sumedha G., Mitchell, Hugh, Garamszegi, Nandor, Edens, Maryanne, Doré, Jules J. E., Leof, Edward B.

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Matrix metalloproteinase 1: role in sarcoma biology by Jawad, Muhammad Umar, Garamszegi, Nandor, Garamszegi, Susanna P, Correa-Medina, Mayrin, Diez, Juan A, Wen, Rong, Scully, Sean P

“…In carcinomas stromal cells participate in cancer progression by producing proteases such as MMPs. The expression MMP1 is a prognostic factor in human…”
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Extracellular Matrix-Induced Gene Expression in Human Breast Cancer Cells by Garamszegi, Nandor, Garamszegi, Susanna P, Shehadeh, Lina A, Scully, Sean P

“…Extracellular matrix (ECM) molecules modify gene expression through attachment-dependent (focal adhesion-related) integrin receptor signaling. It was…”
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siRNA mediated inhibition of MMP-1 reduces invasive potential of a human chondrosarcoma cell line by Jiang, Xiaoling, Dutton, Charyl M., Qi, Wen-ning, Block, Joel A., Garamszegi, Nandor, Scully, Sean P.

“…Matrix metalloproteinases (MMPs) play a crucial role in tumor cell invasion and metastasis. Expression of MMP‐1 has been reported as a prognostic predictor of…”
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Absence of a Correlation between the Presence of a Single Nucleotide Polymorphism in the Matrix Metalloproteinase 1 Promoter and Outcome in Patients of Chondrosarcoma by FONG, Yi-Chin, DUTTON, Charyl M, CHA, Stephen S, GARAMSZEGI, Nandor, SIM, Franklin H, SCULLY, Sean P

“…Purpose: Increased levels of matrix metalloproteinase 1 (MMP-1) expression have been associated with poor outcome in chondrosarcoma. The existence of a single…”
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Noribogaine is a G-protein biased κ-opioid receptor agonist by Maillet, Emeline L., Milon, Nicolas, Heghinian, Mari D., Fishback, James, Schürer, Stephan C., Garamszegi, Nandor, Mash, Deborah C.

“…Noribogaine is the long-lived human metabolite of the anti-addictive substance ibogaine. Noribogaine efficaciously reaches the brain with concentrations up to…”
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Characterization of Noribogaine at nAChRs and Effect on Nicotine Self‐Administration in Rats by Maillet, Emeline, Qing, Chang, Milon, Nicolas, Hanania, Taleen, Heghinian, Mari, Garamszegi, Nandor, Mash, Deborah

“…Abstract only Noribogaine, a polypharmacological drug with activities at opioid receptors, ionotropic nicotinic receptors, and serotonin reuptake transporters,…”
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Noribogaine is a Mixed Agonist/Antagonist Opioid Ligand with Profound Functional Selectivity by Maillet, Emeline, Milon, Nicolas, Fishback, James, Schürer, Stephan, Heghinian, Mari, Garamszegi, Nandor, Mash, Deborah

“…Abstract only Noribogaine is the primary metabolite of the anti‐addictive substance ibogaine, which modulates opiate analgesic activity and the components of…”
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Protein kinase C‐dependent stimulation of phospholipase D in phospholipase C‐treated fibroblasts by Kiss, Zoltan, Garamszegi, Nandor

“…Treatment of [14C]choline‐ or [14C]ethanolamine‐labeled NIH 3T3 fibroblasts withBacillus cereus phosphatidylcholine‐specific phospholipase C (PLC) enhanced…”
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Matrix metalloproteinase‐1 contribution to sarcoma cell invasion by Garamszegi, Nandor, Garamszegi, Susanna P., Scully, Sean P.

“…Matrix metalloproteinase‐1 (MMP‐1) activity has been linked to numerous disease processes from arthritis to ulcer. Its proteolytic activity has been implicated…”
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Transforming growth factor β signaling via ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses by SUZUKI, Kaori, WILKES, Mark C, GARAMSZEGI, Nandor, EDENS, Maryanne, LEOF, Edward B

“…Transforming growth factor beta (TGF-beta) signaling via Smad proteins occurs in various cell types. However, whereas the biological response to TGF-beta can…”
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Molecular mechanism of tenascin-C action on matrix metalloproteinase-1 invasive potential by Galoian, Karine A, Garamszegi, Nandor, Garamszegi, Susanna P, Scully, Sean P

“…The aim of the current study was to confirm that tenascin-C large splice variant (TNC320) stimulates matrix metalloproteinase-1 (MMP-1) expression and to…”
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Transforming Growth Factor {szligbeta} Signaling via Ras in Mesenchymal Cells Requires p21-Activated Kinase 2 for Extracellular Signal-Regulated Kinase-Dependent Transcriptional Responses by Suzuki, Kaori, Wilkes, Mark C, Garamszegi, Nandor, Edens, Maryanne, Leof, Edward B

“…Transforming growth factor {szligbeta} (TGF-{szligbeta}) signaling via Smad proteins occurs in various cell types. However, whereas the biological response to…”
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The Promoter Region of the Human PMCA1 Gene Mediates Transcriptional Downregulation by 1,25-Dihydroxyvitamin D3 by Glendenning, Paul, Ratajczak, Thomas, Prince, Richard L., Garamszegi, Nandor, Strehler, Emanuel E.

“…The gene for plasma membrane calcium pump isoform1 (PMCA1) is expressed in calcium-transporting epithelia and bone mesenchymal cells and is upregulated to…”
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Mechanisms of transforming growth factor-beta receptor endocytosis and intracellular sorting differ between fibroblasts and epithelial cells by Doré, Jr, J J, Yao, D, Edens, M, Garamszegi, N, Sholl, E L, Leof, E B

“…Transforming growth factor-betas (TGF-beta) are multifunctional proteins capable of either stimulating or inhibiting mitosis, depending on the cell type. These…”
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Transforming growth factor beta receptor signaling and endocytosis are linked through a COOH terminal activation motif in the type I receptor by Garamszegi, N, Doré, Jr, J J, Penheiter, S G, Edens, M, Yao, D, Leof, E B

“…Transforming growth factor beta (TGF-beta) coordinates a number of biological events important in normal and pathophysiological growth. In this study, deletion…”
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Heteromeric and Homomeric Transforming Growth Factor-β Receptors Show Distinct Signaling and Endocytic Responses in Epithelial Cells by Doré, Jules J.E., Edens, Maryanne, Garamszegi, Nandor, Leof, Edward B.

“…Transforming growth factor-β (TGF-β) induces distinct responses dependent upon the cellular context. It is unclear whether the initial receptor interactions…”
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Differential Requirement for Type I and Type II Transforming Growth Factor β Receptor Kinase Activity in Ligand-mediated Receptor Endocytosis by Anders, Robert A., Doré, Jules J.E., Arline, Sandra L., Garamszegi, Nandor, Leof, Edward B.

“…Transforming growth factor β (TGFβ) superfamily polypeptides regulate cell growth and differentiation by binding to single pass serine/threonine kinases…”
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Overexpression of protein kinase C- ϵ enhances the stimulatory effect of ethanol on phospholipase C-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts by Kiss, Zoltan, Garamszegi, Nandor

“…Previously, ethanol and the protein kinase C (PKC) activators phorbol 12-myristate 13-acetate (PMA) and bombesin were shown to synergistically stimulate…”
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