Search Results - "Garai, Ildikó"
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Metabolomic Analysis of Serum and Tear Samples from Patients with Obesity and Type 2 Diabetes Mellitus
Published in International journal of molecular sciences (20-04-2022)“…Metabolomics strategies are widely used to examine obesity and type 2 diabetes (T2D). Patients with obesity ( = 31) or T2D ( = 26) and sex- and age-matched…”
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In Vivo Assessments of Mesoblastic Nephroma (Ne/De) and Myelomonoblastic Leukaemia (My1/De) Tumour Development in Hypercholesterolemia Rat Models
Published in International journal of molecular sciences (27-10-2022)“…Given the rising prevalence of lipid metabolic disorders and malignant diseases, we aimed to establish an in vivo hypercholesterinaemic tumour-bearing rat…”
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3
Our experience with the treatment of Hodgkin lymphoma patients
Published in Orvosi hetilap (19-03-2023)“…Overall and disease-free survival of Hodgkin lymphoma patients has improved significantly since the 2000s. This is due to the use of ABVD (adriamycin,…”
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Predicting Complete Cytoreduction with Preoperative [ 18 F]FDG PET/CT in Patients with Ovarian Cancer: A Systematic Review and Meta-Analysis
Published in Diagnostics (Basel) (10-08-2024)“…The cornerstone of ovarian cancer treatment is complete surgical cytoreduction. The gold-standard option in the absence of extra-abdominal metastases and…”
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C-peptide: an essential ally in microvascular complications of type 2 diabetes mellitus and obesity
Published in Diabetology and metabolic syndrome (29-08-2024)“…In order to investigate microvascular complications in metabolic diseases, we aimed to investigate cerebral and peripheral microcirculation in relation to…”
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The Fungal Iron Chelator Desferricoprogen Inhibits Atherosclerotic Plaque Formation
Published in International journal of molecular sciences (03-07-2020)“…Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator…”
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First Line Sorafenib Treatment for Metastatic Medullary Thyroid Cancer: Efficacy and Safety Analysis
Published in Experimental and clinical endocrinology & diabetes (01-04-2019)“…Medullary thyroid cancer (MTC) is a rare disease, the prognosis of advanced and metastatic disease is poor and few therapeutic options are available in this…”
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In Vivo Preclinical Assessment of the VEGF Targeting Potential of the Newly Synthesized [ 52 Mn]Mn-DOTAGA-Bevacizumab Using Experimental Cervix Carcinoma Mouse Model
Published in Diagnostics (Basel) (08-01-2023)“…Among humanized monoclonal antibodies, bevacizumab specifically binds to vascular endothelial growth factor A (VEGF-A). VEGF-A is an overexpressed biomarker in…”
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Synthesis, Physicochemical, Labeling and In Vivo Characterization of 44Sc-Labeled DO3AM-NI as a Hypoxia-Sensitive PET Probe
Published in Pharmaceuticals (Basel, Switzerland) (26-05-2022)“…Hypoxia promotes angiogenesis, which is crucial for tumor growth, and induces malignant progression and increases the therapeutic resistance. Positron emission…”
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10
Changes in Cerebral Blood Flow Detected by SPECT in Type 1 and Type 2 Diabetic Patients
Published in Journal of Nuclear Medicine (01-12-2009)“…Although macrovascular complications are typical for type 2 diabetes mellitus (T2DM), cerebral microvascular damage develops both in type 1 diabetes mellitus…”
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Limitations and pitfalls of 99mTc-EDDA/HYNIC-TOC (Tektrotyd) scintigraphy
Published in Nuclear medicine review. Central & Eastern Europe (29-07-2016)“…Tektrotyd kit was developed by Polatom company for 99mTc labeling to make an alternative tracer of somatostatin receptor scintigraphy available. Since 2005,…”
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[52Mn]Mn‑BPPA-Trastuzumab: A Promising HER2‑Specific PET Radiotracer
Published in Journal of medicinal chemistry (23-05-2024)“…This study aimed to develop a novel radiotracer using trastuzumab and the long-lived [52Mn]Mn isotope for HER2-targeted therapy selection and monitoring. A new…”
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13
Unusual perfusion patterns on perfusion-only SPECT/CT scans in COVID-19 patients
Published in Annals of nuclear medicine (01-09-2022)“…Purpose We aimed at examining both the incidence and extent of different lung perfusion abnormalities as well as the relationship between them on Tc-99m…”
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14
Topological dissimilarities of hierarchical resting networks in type 2 diabetes mellitus and obesity
Published in Journal of computational neuroscience (01-02-2023)“…Type 2 diabetes mellitus (T2DM) is reported to cause widespread changes in brain function, leading to cognitive impairments. Research using resting-state…”
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15
In situ macrophage phenotypic transition is affected by altered cellular composition prior to acute sterile muscle injury
Published in The Journal of physiology (01-09-2017)“…Key points The in situ phenotypic switch of macrophages is delayed in acute injury following irradiation. The combination of bone marrow transplantation and…”
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Impact of intensity discretization on textural indices of [ 18 F]FDG-PET tumour heterogeneity in lung cancer patients
Published in Physics in medicine & biology (20-06-2019)“…Quantifying tumour heterogeneity from [ F]FDG-PET images promises benefits for treatment selection of cancer patients. Here, the calculation of texture…”
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Imaging with [ 99m Tc]HMPAO - a novel perspective: investigation of [ 99m Tc]HMPAO leg muscle uptake in metabolic diseases
Published in Acta radiologica (1987) (01-01-2023)“…Sensitive imaging modalities in the diagnosis of microcircular complications of the lower extremities induced by metabolic diseases are becoming a focus of…”
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Clinical utility of SPECT/CT and CT-dacryocystography-enhanced dacryoscintigraphy in the imaging of lacrimal drainage system obstruction
Published in Annals of nuclear medicine (01-10-2019)“…Purpose Epiphora is commonly caused by a relative or complete occlusion in the lacrimal drainage system (LDS), principally a nasolacrimal duct obstruction…”
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The potential role of FDG PET-CT in the characterization of the activity of Crohn's disease, staging follow-up and prognosis estimation: a pilot study
Published in Scandinavian journal of gastroenterology (02-01-2018)“…Objectives: FDG PET-CT is a global, noninvasive, sensitive method to determine the location and activity of inflammatory lesions. Segmental FDG uptake is…”
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Preclinical evaluation of melanocortin-1 receptor (MC1-R) specific 68Ga- and 44Sc-labeled DOTA-NAPamide in melanoma imaging
Published in European journal of pharmaceutical sciences (30-08-2017)“…Alpha melanocyte stimulating hormone (α-MSH) enhances melanogenesis in melanoma malignum by binding to melanocortin-1 receptors (MC1-R). Earlier studies…”
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