Search Results - "Garín, Marina"

Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells by Garín, Marina I., Chu, Chung-Ching, Golshayan, Dela, Cernuda-Morollón, Eva, Wait, Robin, Lechler, Robert I.

“…The naturally occurring population of dedicated regulatory T cells that coexpress CD4 and CD25 is known to play a key role in the maintenance of peripheral…”
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BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in Bladder Cancer by Martínez, Víctor G, Rubio, Carolina, Martínez-Fernández, Mónica, Segovia, Cristina, López-Calderón, Fernando, Garín, Marina I, Teijeira, Alicia, Munera-Maravilla, Ester, Varas, Alberto, Sacedón, Rosa, Guerrero, Félix, Villacampa, Felipe, de la Rosa, Federico, Castellano, Daniel, López-Collazo, Eduardo, Paramio, Jesús M, Vicente, Ángeles, Dueñas, Marta

“…Bladder cancer is a current clinical and social problem. At diagnosis, most patients present with nonmuscle-invasive tumors, characterized by a high recurrence…”
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Preclinical model for phenotypic correction of dystrophic epidermolysis bullosa by in vivo CRISPR-Cas9 delivery using adenoviral vectors by García, Marta, Bonafont, Jose, Martínez-Palacios, Jesús, Xu, Rudan, Turchiano, Giandomenico, Svensson, Stina, Thrasher, Adrian J., Larcher, Fernando, Del Rio, Marcela, Hernández-Alcoceba, Rubén, Garín, Marina I., Mencía, Ángeles, Murillas, Rodolfo

“…Recessive dystrophic epidermolysis bullosa, a devastating skin fragility disease characterized by recurrent skin blistering, scarring, and a high risk of…”
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The pathogenic Th profile of human activated memory Th cells in early rheumatoid arthritis can be modulated by VIP by Jimeno, Rebeca, Gomariz, Rosa P., Garín, Marina, Gutiérrez-Cañas, Irene, González-Álvaro, Isidoro, Carrión, Mar, Galindo, María, Leceta, Javier, Juarranz, Yasmina

“…Our aim is to study the behavior of memory Th cells (Th17, Th17/1, and Th1 profiles) from early rheumatoid arthritis (eRA) patients after their in vitro…”
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Elongated Flexuous Plant Virus-Derived Nanoparticles Functionalized for Autoantibody Detection by Yuste-Calvo, Carmen, López-Santalla, Mercedes, Zurita, Lucía, Cruz-Fernández, César F., Sánchez, Flora, Garín, Marina I., Ponz, Fernando

“…Nanoparticles derived from the elongated flexuous capsids of Turnip mosaic virus (TuMV) have been shown to be efficient tools for antibody sensing with a very…”
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Th17 polarization of memory Th cells in early arthritis: the vasoactive intestinal peptide effect by Jimeno, Rebeca, Leceta, Javier, Garín, Marina, Ortiz, Ana M., Mellado, Mario, Rodríguez‐Frade, Jose Miguel, Martínez, Carmen, Pérez‐García, Selene, Gomariz, Rosa P., Juarranz, Yasmina

“…Th17 cells from eRA patients are prone to expand to a pathological cell population under Th17‐polarizing conditions where VIP prevents their pathogenesis…”
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Vasoactive Intestinal Peptide Maintains the Nonpathogenic Profile of Human Th17-Polarized Cells by Jimeno, Rebeca, Leceta, Javier, Martínez, Carmen, Gutiérrez-Cañas, Irene, Carrión, Mar, Pérez-García, Selene, Garín, Marina, Mellado, Mario, Gomariz, Rosa P., Juarranz, Yasmina

“…The cytokine microenvironment modulates CD4 T cell differentiation causing the shift of naïve CD4 T cells into different cell subsets. This process is also…”
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Akt Activation Synergizes with Trp53 Loss in Oral Epithelium to Produce a Novel Mouse Model for Head and Neck Squamous Cell Carcinoma by MORAL, Marta, SEGRELLES, Carmen, COSTA, Clotilde, SAIZ, Cristina, RODRIGUEZ-PERALTO, Jose L, MARTINEZ-TELLO, Francisco J, RODRIGUEZ-PINILLA, Maria, SANCHEZ-CESPEDES, Montserrat, GARIN, Marina, GRANDE, Teresa, BRAVO, Ana, DIGIOVANNI, John, LARA, M. Fernanda, PARAMIO, Jesús M, MARTINEZ-CRUZ, Ana Belén, LORZ, Corina, SANTOS, Mirentxu, GARCIA-ESCUDERO, Ramón, LU, Jerry, KIGUCHI, Kaoru, BUITRAGO, Agueda

“…Head and neck squamous cell carcinoma (HNSCC) is a common human neoplasia with poor prognosis and survival that frequently displays Akt overactivation. Here we…”
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Down-regulated expression of hsa-miR-181c in Fanconi anemia patients: implications in TNFα regulation and proliferation of hematopoietic progenitor cells by Río, Paula, Agirre, Xabier, Garate, Leire, Baños, Rocío, Álvarez, Lara, San José-Enériz, Edurne, Badell, Isabel, Casado, José A., Garín, Marina, Prósper, Felipe, Bueren, Juan A.

“…Fanconi anemia (FA) is an inherited genetic disorder associated with BM failure and cancer predisposition. In the present study, we sought to elucidate the…”
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IKKβ Leads to an Inflammatory Skin Disease Resembling Interface Dermatitis by Page, Angustias, Navarro, Manuel, Garín, Marina, Pérez, Paloma, Llanos Casanova, M., Moreno, Rodolfo, Jorcano, José L., Cascallana, José L., Bravo, Ana, Ramírez, Angel

“…IKKβ is a subunit of the IκB kinase (IKK) complex required for NF-κB activation in response to pro-inflammatory signals. NF-κB regulates the expression of many…”
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A Functional Role of RB-Dependent Pathway in the Control of Quiescence in Adult Epidermal Stem Cells Revealed by Genomic Profiling by Lorz, Corina, García-Escudero, Ramón, Segrelles, Carmen, Garín, Marina I., Ariza, José M., Santos, Mirentxu, Ruiz, Sergio, Lara, María F., Martínez-Cruz, Ana B., Costa, Clotilde, Buitrago-Pérez, Águeda, Saiz-Ladera, Cristina, Dueñas, Marta, Paramio, Jesús M.

“…Continuous cell renewal in mouse epidermis is at the expense of a pool of pluripotent cells that lie in a well defined niche in the hair follicle known as the…”
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Mesenchymal Stem/Stromal Cells for Rheumatoid Arthritis Treatment: An Update on Clinical Applications by Lopez-Santalla, Mercedes, Fernandez-Perez, Raquel, Garin, Marina I

“…Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects the lining of the synovial joints leading to stiffness, pain, inflammation,…”
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Mesenchymal stem/stromal cell-based therapy for the treatment of rheumatoid arthritis: An update on preclinical studies by Lopez-Santalla, Mercedes, Bueren, Juan A., Garin, Marina I.

“…Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and progressive joint destruction and is a primary…”
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Mechanism of Immunoregulatory Properties of Vasoactive Intestinal Peptide in the K/BxN Mice Model of Autoimmune Arthritis by Leceta, Javier, Garin, Marina I, Conde, Carmen

“…The K/BxN mouse model of rheumatoid arthritis (RA) closely resembles the human disease. In this model, arthritis results from activation of autoreactive KRN T…”
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Assessment of mesenchymal stem/stromal cell-based therapy in K/BxN serum transfer-induced arthritis by Lopez-Santalla, Mercedes, Conde, Carmen, Rodriguez-Trillo, Angela, Garin, Marina I

“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial hyperplasia and cartilage/bone destruction with systemic comorbidities. Despite…”
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Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis by Toupet, Karine, Maumus, Marie, Luz-Crawford, Patricia, Lombardo, Eleuterio, Lopez-Belmonte, Juan, van Lent, Peter, Garin, Marina I, van den Berg, Wim, Dalemans, Wilfried, Jorgensen, Christian, Noël, Danièle

“…Application of mesenchymal stem/stromal cells (MSCs) in treating different disorders, in particular osteo-articular diseases, is currently under investigation…”
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Isolation of adult mouse stem keratinocytes using magnetic cell sorting (MACS) by Lorz, Corina, Segrelles, Carmen, Garín, Marina, Paramio, Jesús M

“…The functional and molecular characterization of mouse epidermal stem cells (SC) requires in many circumstances arduous technologies and elaboration of…”
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Corrigendum: Assessment of mesenchymal stem/stromal cell-based therapy in K/BxN serum transfer-induced arthritis by Lopez-Santalla, Mercedes, Conde, Carmen, Rodriguez-Trillo, Angela, Garin, Marina I

“…[This corrects the article DOI: 10.3389/fimmu.2022.943293.]…”
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Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis by Fernandez-Perez, Raquel, Lopez-Santalla, Mercedes, Sánchez-Domínguez, Rebeca, Alberquilla, Omaira, Gutiérrez-Cañas, Irene, Juarranz, Yasmina, Bueren, Juan A, Garin, Marina I

“…Galectin-1 is a -galactoside-binding lectin, ubiquitously expressed in stromal, epithelial, and different subsets of immune cells. Galectin-1 is the prototype…”
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Human Adipose‐Derived Mesenchymal Stem Cells Modulate Experimental Autoimmune Arthritis by Modifying Early Adaptive T Cell Responses by Lopez‐Santalla, Mercedes, Mancheño‐Corvo, Pablo, Menta, Ramon, Lopez‐Belmonte, Juan, DelaRosa, Olga, Bueren, Juan A., Dalemans, Wilfried, Lombardo, Eleuterio, Garin, Marina I.

“…Mesenchymal stem cells (MSCs) are multipotent stromal cells with immunosuppressive properties. They have emerged as a very promising treatment for autoimmunity…”
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