Search Results - "Gapys, Beata"
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Protective effects of voltage-gated calcium channel antagonists against zinc toxicity in SN56 neuroblastoma cholinergic cells
Published in PloS one (20-12-2018)“…One of the pathological site effects in excitotoxic activation is Zn2+ overload to postsynaptic neurons. Such an effect is considered to be equivalent to the…”
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Aggravated effects of coexisting marginal thiamine deficits and zinc excess on SN56 neuronal cells
Published in Nutritional neuroscience (03-06-2021)“…Objectives: Zinc excitotoxicity and thiamine pyrophosphate deficiency (TD) are known pathogenic signals contributing to mechanism of different encephalopathies…”
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Phenotype-Dependent Interactions between N-acetyl-L-Aspartate and Acetyl-CoA in Septal SN56 Cholinergic Cells Exposed to an Excess of Zinc
Published in Journal of Alzheimer's disease (01-01-2017)“…Pyruvate dehydrogenase reaction utilizing glucose-derived pyruvate is an almost exclusive source of acetyl-CoA in different cell mitochondrial compartments of…”
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Deficits of thiamine pyrophosphate in glial cells
Published in Folia neuropathologica (01-01-2013)“…Thiamine deficits inhibit metabolic fluxes through pyruvate and ketoglutarate dehydrogenase steps yielding inhibition of acetyl-CoA and energy production in…”
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