Search Results - "Gao, Yurou"
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Assessment of the disruption effects of tetrabromobisphenol A and its analogues on lipid metabolism using multiple in vitro models
Published in Ecotoxicology and environmental safety (15-07-2024)“…Tetrabromobisphenol A (TBBPA), a widely-used brominated flame retardant, has been revealed to exert endocrine disrupting effects and induce adipogenesis. Given…”
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3-tert-Butyl-4-hydroxyanisole perturbs renal lipid metabolism in vitro by targeting androgen receptor-regulated de novo lipogenesis
Published in Ecotoxicology and environmental safety (15-06-2023)“…The widespread usage of 3-tert-butyl-4-hydroxyanisole (3-BHA) as an anthropogenic antioxidant has caused considerable environmental contamination and frequent…”
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A high-throughput assay for screening the abilities of per- and polyfluoroalkyl substances in inducing plasma kallikrein-like activity
Published in Ecotoxicology and environmental safety (01-04-2022)“…The plasma consists of multiple functional serine zymogens, such as plasma kallikrein-kinin system (KKS), which are vulnerable to exogenous chemical exposure,…”
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The exon 19-deleted EGFR undergoes ubiquitylation-mediated endocytic degradation via dynamin activity-dependent and -independent mechanisms
Published in Cell communication and signaling (05-07-2018)“…The epidermal growth factor receptor (EGFR) is closely implicated in cancer, and sequencing analyses have revealed a high mutation rate of EGFR in lung cancer…”
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Chemical contaminants in blood and their implications in chronic diseases
Published in Journal of hazardous materials (15-03-2024)“…Artificial chemical products are widely used and ubiquitous worldwide and pose a threat to the environment and human health. Accumulating epidemiological and…”
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Toward the Integration of Machine Learning and Molecular Modeling for Designing Drug Delivery Nanocarriers
Published in Advanced materials (Weinheim) (01-11-2024)“…The pioneering work on liposomes in the 1960s and subsequent research in controlled drug release systems significantly advances the development of nanocarriers…”
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Perfluorinated Iodine Alkanes Promoted Neural Differentiation of mESCs by Targeting miRNA-34a-5p in Notch-Hes Signaling
Published in Environmental science & technology (21-06-2022)“…The neurodevelopmental process is highly vulnerable to environmental stress from exposure to endocrine-disrupting chemicals. Perfluorinated iodine alkanes…”
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Tracing the plasma kallikrein-kinin system-activating component in the atmospheric particulate matter with different origins
Published in Journal of hazardous materials (15-09-2023)“…Atmospheric particulate matter (PM) perturbs hematological homeostasis by targeting the plasma kallikrein-kinin system (KKS), causing a cascade of zymogen…”
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The Plasma Kallikrein-Kinin System: A Hematological Target for Environmental Contaminants
Published in Current pollution reports (01-09-2024)“…Purpose of Review The increasing occurrence of emerging chemicals of concern in the environment has caused high public attention. Assessing their hematologic…”
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Dynasore-induced potent ubiquitylation of the exon 19 deletion mutant of epidermal growth factor receptor suppresses cell growth and migration in non-small cell lung cancer
Published in The international journal of biochemistry & cell biology (01-12-2018)“…Lung cancer is a leading cause of death worldwide, with mutations in EGFR frequently detected that render this receptor tyrosine kinase constantly active…”
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