Search Results - "Gao, Yingsheng"

Chitosan Oligosaccharide Ameliorates Nonalcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Mice by Qian, Minyi, Lyu, Qianqian, Liu, Yujie, Hu, Haiyang, Wang, Shilei, Pan, Chuyue, Duan, Xubin, Gao, Yingsheng, Qi, Lian-Wen, Liu, Weizhi, Wang, Lirui

“…Nonalcoholic fatty liver disease (NAFLD) is a global epidemic, and there is no standard and efficient therapy for it. Chitosan oligosaccharide (COS) is widely…”
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The first selective VAP-1 inhibitor in China, TT-01025-CL: safety, tolerability, pharmacokinetics, and pharmacodynamics of single- and multiple-ascending doses by Yang, Yuanxun, Yu, Lei, Sheng, Zejuan, Lin, Hui, Weng, Zuyi, Song, Wei, Cao, Bei, Zhao, Yu, Gao, Yingsheng, Ni, Shumao, Wang, Huimin, Ma, Tingting, Huang, Lei, Sun, Caixia, Li, Juan

“…TT-01025-CL is an oral, irreversible small molecule that potently inhibits vascular adhesion protein-1 (VAP-1) for the treatment of inflammation associated…”
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Discovery of a novel orally bioavailable NLRP3 inflammasome inhibitor, TTS-X, for potential treatment of inflammatory bowel disease by Gao, Yingsheng, Li, Lin, Pan, Shan, Gao, You, Zhao, Zheng, Wu, Di, Sheng, Zejuan, Wu, Yongqian

“…Abstract Inappropriate activation of the NLRP3 inflammasome has been implicated in multiple inflammatory diseases, including inflammatory bowel disease…”
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TP53 Mutations Promote Immunogenic Activity in Breast Cancer by Chen, Cai, Wang, Lirui, Gao, Yingsheng, Jiang, Zehang, Liu, Zhixian, Wang, Xiaosheng

“…Background. Although immunotherapy has recently achieved clinical successes in a variety of cancers, thus far there is no immunotherapeutic strategy for breast…”
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Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans by Pan, Chuyue, Liu, Jun, Gao, Yingsheng, Yang, Maohui, Hu, Haiyang, Liu, Chang, Qian, Minyi, Yuan, Hai-Yang, Yang, Song, Zheng, Ming-Hua, Wang, Lirui

“…Metabolic dysfunction-associated steatohepatitis (MASH) is a leading risk factor for liver cirrhosis and hepatocellular carcinoma. Here, we report that CHRNA4,…”
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Coordinated changes of gut microbiome and lipidome differentiates nonalcoholic steatohepatitis (NASH) from isolated steatosis by Qian, Minyi, Hu, Haiyang, Yao, Ying, Zhao, Danyang, Wang, Shilei, Pan, Chuyue, Duan, Xubin, Gao, Yingsheng, Liu, Jun, Zhang, Yufei, Yang, Song, Qi, Lian‐Wen, Wang, Lirui

“…Background & Aims Nonalcoholic fatty liver disease encompasses isolated steatosis or nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH). NASH…”
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Sa1628 – Coordinated Changes of Gut Microbiome and Lipidome Differentiates Nonalcoholic Steatohepatitis (NASH) from Isolated Steatosis by Qian, Minyi, Hu, Haiyang, Wang, Shilei, Pan, Chuyue, Duan, Xubin, Gao, Yingsheng, Qi, Lianwen, Wang, Lirui

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715 ARYL HYDROCARBON RECEPTOR DEFICIENCY IN INTESTINAL EPITHELIAL CELLS AGGRAVATES ALCOHOL-RELATED LIVER DISEASE by Qian, Minyi, Liu, Jun, Zhao, Danyang, Pan, Chuyue, Jia, Wenxin, Gao, Yingsheng, Zhang, Yufei, Yang, Song, Zhang, Nan, Zhang, Yinan, Zhang, Quan, Wu, Dalei, Schnabl, Bernd, Shen, Xu, Wang, Lirui

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Aryl Hydrocarbon Receptor Deficiency in Intestinal Epithelial Cells Aggravates Alcohol-Related Liver Disease by Qian, Minyi, Liu, Jun, Zhao, Danyang, Cai, Pengpeng, Pan, Chuyue, Jia, Wenxin, Gao, Yingsheng, Zhang, Yufei, Zhang, Nan, Zhang, Yinan, Zhang, Quan, Wu, Dalei, Shan, Chengjie, Zhang, Meiling, Schnabl, Bernd, Yang, Song, Shen, Xu, Wang, Lirui

“…The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues. Roles of Ahr in…”
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Aryl Hydrocarbon Receptor Deficiency in Intestinal Epithelial Cells Aggravates Alcohol-Related Liver DiseaseSummary by Minyi Qian, Jun Liu, Danyang Zhao, Pengpeng Cai, Chuyue Pan, Wenxin Jia, Yingsheng Gao, Yufei Zhang, Nan Zhang, Yinan Zhang, Quan Zhang, Dalei Wu, Chengjie Shan, Meiling Zhang, Bernd Schnabl, Song Yang, Xu Shen, Lirui Wang

“…Background & Aims: The ligand-activated transcription factor, aryl hydrocarbon receptor (AHR) can sense xenobiotics, dietary, microbial, and metabolic cues…”
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TGF-β1 Causes EMT by Regulating N-Acetyl Glucosaminyl Transferases via Downregulation of Non Muscle Myosin II-A through JNK/P38/PI3K Pathway in Lung Cancer by Khan, Ghulam Jilany, Gao, Yingsheng, Gu, Ming, Wang, Lai, Khan, Sara, Naeem, Farah, Semukunzi, Herve, Roy, Debmalya, Yuan, Shengtao, Sun, Li

“…Epithelial to mesenchymal transition (EMT) is a major determinant of cancer metastasis and is closely linked with TGF-β1. Intracellular proteins, including E…”
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