Search Results - "Gao, Wenda"

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells by BETTELLI, Estelle, CARRIER, Yijun, WENDA GAO, KORN, Thomas, STROM, Terry B, OUKKA, Mohamed, WEINER, Howard L, KUCHROO, Vijay K

“…On activation, T cells undergo distinct developmental pathways, attaining specialized properties and effector functions. T-helper (T(H)) cells are…”
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In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche by Fujisaki, Joji, Wu, Juwell, Carlson, Alicia L., Silberstein, Lev, Putheti, Prabhakar, Larocca, Rafael, Gao, Wenda, Saito, Toshiki I., Celso, Cristina Lo, Tsuyuzaki, Hitoshi, Sato, Tatsuyuki, Côté, Daniel, Sykes, Megan, Strom, Terry B., Scadden, David T., Lin, Charles P.

“…A privileged position A new study identifies the bone marrow haematopoietic stem cell (HSC) niche — a specialized microenvironment where stem cells reside — as…”
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Leucinostatins from fungal extracts block malaria transmission to mosquitoes by Niu, Guodong, Wang, Xiaohong, Gao, Wenda, Cui, Liwang, Li, Jun

“…Malaria is a mosquito-transmitted disease that kills more than half a million people annually. The lack of effective malaria vaccines and recently increasing…”
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The Pathogenic Roles of IL-22 in Colitis: Its Transcription Regulation by Musculin in T Helper Subsets and Innate Lymphoid Cells by Yan, Jun, Yu, Jing, Liu, Ke, Liu, Yijia, Mao, Changchuin, Gao, Wenda

“…IL-22 plays a crucial role in promoting inflammation, antimicrobial immunity and tissue repair at barrier surfaces. The role of IL-22 in colitis is still…”
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Glycoengineered anti-CD39 promotes anticancer responses by depleting suppressive cells and inhibiting angiogenesis in tumor models by Zhang, Haohai, Feng, Lili, de Andrade Mello, Paola, Mao, Changchuin, Near, Richard, Csizmadia, Eva, Chan, Leo Li-Ying, Enjyoji, Keiichi, Gao, Wenda, Zhao, Haitao, Robson, Simon C

“…Immunosuppressive cells accumulating in the tumor microenvironment constitute a formidable barrier that interferes with current immunotherapeutic approaches. A…”
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Cd39 and P2rx7-Wnt signaling enhance blast pathogenicity in an experimental model of acute myeloid leukemia by Feng, Lili, Zhang, Haohai, Mao, Changchuin, De Andrade Mello, Paola, Stroopinsky, Dina, Csizmadia, Eva, Zhou, Jialin, Avigan, David, Yu, Jinming, Gao, Wenda, Robson, Simon C

“…Not available.Not available…”
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Structures and biological functions of IL-31 and IL-31 receptors by Zhang, Qing, Putheti, Prabhakar, Zhou, Qiang, Liu, Quansheng, Gao, Wenda

“…Abstract Interleukin-31, produced mainly by activated CD4+ T cells, is a newly discovered member of the gp130/IL-6 cytokine family. Unlike all the other family…”
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Risk Factors of Cervical Anastomotic Leakage after McKeown Minimally Invasive Esophagectomy: Focus on Preoperative and Intraoperative Lung Function by Gao, Wenda, Wang, Mingbo, Su, Peng, Zhang, Fan, Huang, Chao, Tian, Ziqiang

“…Background: Cervical anastomotic leakage (CAL) is one of the most common complications that occur minimally invasive esophagectomy (MIE). It is associated with…”
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OX40 costimulation turns off Foxp3+ Tregs by Vu, Minh Diem, Xiao, Xiang, Gao, Wenda, Degauque, Nicolas, Chen, Ming, Kroemer, Alexander, Killeen, Nigel, Ishii, Naoto, Chang Li, Xian

“…OX40 is a recently identified T-cell costimulatory molecule that belongs to the TNF/TNFR superfamily. OX40 can be expressed by both activated T effector cells…”
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IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation by Ren, Cuiping, Liu, Fengchun, Xing, Chen, Zhao, Ruyu, Tang, Xiaoxue, Liu, Miao, Gao, Wenda, Shen, Jijia

“…Abstract Background Hepatic macrophages regulate liver granuloma formation and fibrosis caused by infection with Schistosoma japonicum , with the manner of…”
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Targeting chemoresistance and mitochondria-dependent metabolic reprogramming in acute myeloid leukemia by Feng, Lili, Zhang, Philip Y, Gao, Wenda, Yu, Jinming, Robson, Simon C

“…Chemoresistance often complicates the management of cancer, as noted in the instance of acute myeloid leukemia (AML). Mitochondrial function is considered…”
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Lack of IL-17 signaling decreases liver fibrosis in murine schistosomiasis japonica by Zhang, Yuxia, Huang, Dake, Gao, Wenda, Yan, Jun, Zhou, Wanling, Hou, Xin, Liu, Miao, Ren, Cuiping, Wang, Siying, Shen, Jijia

“…Accumulating evidence has identified the profibrogenic properties of IL-17A in organ fibrosis. However, the role of IL-17A signal in liver fibrosis induced by…”
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PD-L2 expression extends beyond dendritic cells/macrophages to B1 cells enriched for VH11/VH12 and phosphatidylcholine binding by Zhong, Xuemei, Tumang, Joseph R, Gao, Wenda, Bai, Chunyan, Rothstein, Thomas L

“…B1 B cells are the major source of natural antibody that is essential for innate immunity. The B1 repertoire is skewed toward production of phosphatidylcholine…”
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Musculin Deficiency Aggravates Colonic Injury and Inflammation in Mice with Inflammatory Bowel Disease by Yu, Jing, Liu, Yijia, Zhang, Wei, Yang, Xue, Tang, Wanqi, Liang, Huaping, Li, Suiyan, Gao, Wenda, Yan, Jun

“…Intestinal inflammatory reactions and resulting tissue injuries are two major aspects of inflammatory bowel disease (IBD). The regulatory factors involved in…”
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IL‐17 neutralization significantly ameliorates hepatic granulomatous inflammation and liver damage in Schistosoma japonicum infected mice by Zhang, Yuxia, Chen, Liuxi, Gao, Wenda, Hou, Xin, Gu, Yuqing, Gui, Li, Huang, Dake, Liu, Miao, Ren, Cuiping, Wang, Siying, Shen, Jijia

“…IL‐17 is a signature cytokine of Th17 cells implicated in the induction and progression of chronic inflammatory diseases. Several studies in C57BL/6 mice,…”
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Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors by Crowley, Andrew R, Osei-Owusu, Nana Yaw, Dekkers, Gillian, Gao, Wenda, Wuhrer, Manfred, Magnani, Diogo M, Reimann, Keith A, Pincus, Seth H, Vidarsson, Gestur, Ackerman, Margaret E

“…Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a…”
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Pan-neutralizing, germline-encoded antibodies against SARS-CoV-2: Addressing the long-term problem of escape variants by Lunderberg, Justin Mark, Dutta, Sanjucta, Collier, Ai-Ris Y., Lee, Jeng-Shin, Hsu, Yen-Ming, Wang, Qiao, Zheng, Weina, Hao, Shushun, Zhang, Haohai, Feng, Lili, Robson, Simon C., Gao, Wenda, Riedel, Stefan

“…Despite the initially reported high efficacy of vaccines directed against ancestral SARS-CoV-2, repeated infections in both unvaccinated and vaccinated…”
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Application of three-dimensional computed tomography bronchography and angiography in thoracoscopic anatomical segmentectomy of the right upper lobe: A cohort study by Wang, Mingbo, Lv, Huilai, Wu, Tao, Gao, Wenda, Tian, Yang, Gai, Chunyue, Tian, Ziqiang

“…Objective Three-dimensional computed tomography bronchography and angiography (3D-CTBA) can provide detailed imaging information for pulmonary segmentectomy…”
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Immuno-isolation of pancreatic islet allografts using pegylated nanotherapy leads to long-term normoglycemia in full MHC mismatch recipient mice by Dong, Huansheng, Fahmy, Tarek M, Metcalfe, Su M, Morton, Steve L, Dong, Xiao, Inverardi, Luca, Adams, David B, Gao, Wenda, Wang, Hongjun

“…Two major hurdles need to be surmounted for cell therapy for diabetes: (i) allo-immune rejection of grafted pancreatic islets, or stem/precursor cell-derived…”
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Reciprocal generation of Th1/Th17 and Treg cells by B1 and B2 B cells by Zhong, Xuemei, Gao, Wenda, Degauque, Nicolas, Bai, Chunyan, Lu, Yan, Kenny, James, Oukka, Mohamed, Strom, Terry B, Rothstein, Thomas L

“…Regulatory T (Treg) cells are indispensable for maintaining peripheral tolerance, whereas T helper (Th)1 and Th17 cells induce inflammation and tissue…”
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