Search Results - "Gao, Kejian"
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Direct quantification of N6-methyladenosine fractions at specific site in RNA based on deoxyribozyme mediated CRISPR-Cas12a platform
Published in Talanta (Oxford) (01-01-2025)“…As the most abundant modification in eukaryotic messenger RNA (mRNA) and long noncoding RNA (lncRA), N6-methyladenosine (m6A) has been shown to play essential…”
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Direct quantification of N-methyladenosine fractions at specific site in RNA based on deoxyribozyme mediated CRISPR-Cas12a platform
Published in Talanta (Oxford) (01-01-2025)Get full text
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A simple, portable and multiplex LAMP-based CRISPR/Cas12a assay for visually screening genetically modified crops
Published in Sensors and actuators. B, Chemical (15-03-2024)Get full text
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Ultrasensitive and visual detection of genetically modified crops using two primers-induced cascade exponential amplification assay
Published in Talanta (Oxford) (01-02-2024)“…The increased global cultivation area of genetically modified (GM) crops has caused severe controversies over potential health and environmental risks…”
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A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction
Published in Chemical science (Cambridge) (07-02-2018)“…Sensitive and accurate detection of site-specific DNA methylation is of critical significance for early diagnosis of human diseases, especially cancers…”
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Specific quantitative detection of N6-methyladenosine at single-base resolution by extension-based isothermal exponential amplification reaction (E-IEXPAR)
Published in Analytica chimica acta (08-05-2024)“…N6-methyladenosine (m6A) is a common modification in RNA, crucial for various cellular functions and associated with human diseases. Quantification of m6A at…”
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7
CRISPR/Cas13a induced exponential amplification for highly sensitive and specific detection of circular RNA
Published in Talanta (Oxford) (15-08-2022)“…Rapid, sensitive and specific determination of circular RNA (circRNA) is of great significance for both biological research and clinical diagnosis. Specific…”
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Multiple thermocycles followed by LAMP with only two primers for ultrasensitive colorimetric viral RNA testing and tracking at single-base resolution
Published in Analytica chimica acta (02-10-2023)“…Rapid, accurate and high throughput measurement of infectious viruses is an urgent need to prevent viral transmission. Loop-mediated isothermal amplification…”
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Ultrasensitive detection of circular RNA by accurate recognition of the specific junction site using stem-loop primer induced double exponential amplification
Published in Talanta (Oxford) (01-09-2020)“…Circular RNAs (circRNAs), as a class of newly emerging biomarkers, have shown to be associated with many fundamental life processes and diseases, especially…”
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10
Direct quantification of N 6 -methyladenosine fractions at specific site in RNA based on deoxyribozyme mediated CRISPR-Cas12a platform
Published in Talanta (Oxford) (05-09-2024)“…As the most abundant modification in eukaryotic messenger RNA (mRNA) and long noncoding RNA (lncRA), N -methyladenosine (m A) has been shown to play essential…”
Get full text
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11
Specific quantitative detection of N 6 -methyladenosine at single-base resolution by extension-based isothermal exponential amplification reaction (E-IEXPAR)
Published in Analytica chimica acta (08-05-2024)“…N -methyladenosine (m A) is a common modification in RNA, crucial for various cellular functions and associated with human diseases. Quantification of m A at…”
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12
A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reactionElectronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04975g
Published 31-01-2018“…Sensitive and accurate detection of site-specific DNA methylation is of critical significance for early diagnosis of human diseases, especially cancers…”
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13
A novel restriction endonuclease GlaI for rapid and highly sensitive detection of DNA methylation coupled with isothermal exponential amplification reaction† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04975g
Published in Chemical science (Cambridge) (11-12-2017)“…An elegant GlaI–EXPAR strategy is proposed which allows accurate detection of site-specific DNA methylations with ultrahigh sensitivity and specificity…”
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14
Genetic Association Between CDKN1B rs2066827 Polymorphism and Susceptibility to Cancer
Published in Medicine (Baltimore) (01-11-2015)“…Much attention has been directed to the association between cancer risk and rs2066827 polymorphism of the CDKN1B gene. However, the results are indefinitive…”
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The role of O6-methylguanine-DNA methyltransferase polymorphisms in colorectal cancer susceptibility: a meta analysis
Published in International journal of clinical and experimental medicine (15-01-2015)“…Objective: O 6 -methylguanine DNA methyl-transferase gene ( MGMT ) is a central DNA repair mechanism with a significant role in removing DNA damage caused by…”
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The role of O(6)-methylguanine-DNA methyltransferase polymorphisms in colorectal cancer susceptibility: a meta analysis
Published in International journal of clinical and experimental medicine (2015)“…O(6)-methylguanine DNA methyl-transferase gene (MGMT) is a central DNA repair mechanism with a significant role in removing DNA damage caused by alkylating…”
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17
Robust genome editing of CRISPR-Cas9 at NAG PAMs in rice
Published in Science China. Life sciences (2018)“…Dear Editor,The CRISPR-Cas9(clustered regularly interspaced short palindromic repeats/Cas9)system has been widely used for a variety of applications,including…”
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18
Surface molecularly imprinted polymers for solid-phase extraction of (–)-epigallocatechin gallate from toothpaste
Published in Frontiers of chemical science and engineering (01-12-2015)“…Surface molecularly imprinted polymers (SMIPs) have been synthesized to selectively determine (–)-epigallocatechin gallate in aqueous media. SMIPs were…”
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