Search Results - "Gao, Jimin"

A Graphene Oxide-Based Fluorescent Biosensor for the Analysis of Peptide–Receptor Interactions and Imaging in Somatostatin Receptor Subtype 2 Overexpressed Tumor Cells by Feng, Bianying, Guo, Linjie, Wang, Lihua, Li, Fan, Lu, Jianxin, Gao, Jimin, Fan, Chunhai, Huang, Qing

“…Analysis of peptide–receptor interactions provides insights for understanding functions of proteins in cells. In this work, we report the development of a…”
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Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression by Liu, Juan, Zhang, Cen, Zhao, Yuhan, Yue, Xuetian, Wu, Hao, Huang, Shan, Chen, James, Tomsky, Kyle, Xie, Haiyang, Khella, Christen A., Gatza, Michael L., Xia, Dajing, Gao, Jimin, White, Eileen, Haffty, Bruce G., Hu, Wenwei, Feng, Zhaohui

“…Mutations in E3 ubiquitin ligase Parkin have been linked to familial Parkinson’s disease. Accumulating evidence suggests that Parkin is a tumor suppressor, but…”
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Ultrasensitive Electrochemical Detection of Prostate-Specific Antigen by Using Antibodies Anchored on a DNA Nanostructural Scaffold by Chen, Xiaoqing, Zhou, Guobao, Song, Ping, Wang, Jingjing, Gao, Jimin, Lu, Jianxin, Fan, Chunhai, Zuo, Xiaolei

“…The high occurrence of prostate cancer in men makes the prostate-specific antigen (PSA) screening test really important. More importantly, the recurrence rate…”
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Nanomaterial-Based Fluorescent DNA Analysis: A Comparative Study of the Quenching Effects of Graphene Oxide, Carbon Nanotubes, and Gold Nanoparticles by Li, Fan, Pei, Hao, Wang, Lihua, Lu, Jianxin, Gao, Jimin, Jiang, Bowei, Zhao, Xingchun, Fan, Chunhai

“…A variety of nanomaterials have shown extraordinarily high quenching ability toward a broad range of fluorophores. Recently, there has been intense interest in…”
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Gold Nanoparticle-Based Enzyme-Linked Antibody-Aptamer Sandwich Assay for Detection of Salmonella Typhimurium by Wu, Wenhe, Li, Jun, Pan, Dun, Li, Jiang, Song, Shiping, Rong, Mingge, Li, Zixi, Gao, Jimin, Lu, Jianxin

“…Enzyme-linked immunosorbent assay (ELISA) provides a convenient means for the detection of Salmonella enterica serovar Typhimurium (STM), which is important…”
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Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses by Yang, Jialong, Lin, Xingguang, Pan, Yun, Wang, Jinli, Chen, Pengcheng, Huang, Hongxiang, Xue, Hai-Hui, Gao, Jimin, Zhong, Xiao-Ping

“…T follicular helper (Tfh) cells play critical roles for germinal center responses and effective humoral immunity. We report here that mTOR in CD4 T cells is…”
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A thermoresponsive nanocarrier for mitochondria-targeted drug delivery by Wang, Dongqing, Huang, Hui, Zhou, Mengxue, Lu, Huiru, Chen, Jun, Chang, Young-Tae, Gao, Jimin, Chai, Zhifang, Hu, Yi

“…Mitochondria emerge as an important target for cancer therapy. Herein, by taking advantage of the recently reported high temperature of mitochondria, a…”
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dumbbell probe-mediated rolling circle amplification strategy for highly sensitive microRNA detection by Zhou, Yuntao, Huang, Qing, Gao, Jimin, Lu, Jianxin, Shen, Xizhong, Fan, Chunhai

“…We herein report the design of a dumbbell-shaped DNA probe that integrates target-binding, amplification and signaling within one multifunctional design. The…”
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PD‐1 blockade enhances the antitumor efficacy of GM‐CSF surface‐modified bladder cancer stem cells vaccine by Shi, Xiaojun, Zhang, Xinji, Li, Jinlong, Mo, Lijun, Zhao, Hongfan, Zhu, Yongtong, Hu, Zhiming, Gao, Jimin, Tan, Wanlong

“…Eliminating cancer stem cells (CSCs) is a key issue in eradicating tumor. The streptavidin–granulocyte‐macrophage‐colony stimulating factor (SA–GM‐CSF)…”
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Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages by Deng, Wenhai, Yang, Jialong, Lin, Xingguang, Shin, Jinwook, Gao, Jimin, Zhong, Xiao-Ping

“…Alveolar macrophages (AMϕ) have the capacity of local self-renewal through adult life; however, mechanisms that regulate AMϕ self-renewal remain poorly…”
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Development of Nectin4/FAP-targeted CAR-T cells secreting IL-7, CCL19, and IL-12 for malignant solid tumors by Li, Fanfan, Zhao, Shuping, Wei, Cheng, Hu, Yaodi, Xu, Tianlong, Xin, Xueyi, Zhu, Tingwei, Shang, Liting, Ke, Shanwen, Zhou, Jiang, Xu, Xiaojun, Gao, Yue, Zhao, Ai, Gao, Jimin

“…Chimeric antigen receptor T (CAR-T) cell therapy has made significant advances for hematological malignancies but encounters obstacles in the treatment of…”
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JNK1 Mediates Degradation HIF-1α by a VHL-Independent Mechanism that Involves the Chaperones Hsp90/Hsp70 by DONGYUN ZHANG, JINGXIA LI, COSTA, Max, JIMIN GAO, CHUANSHU HUANG

“…Abstract Hypoxia-inducible factor-1α (HIF-1α) is a master transcription factor that is critical for the regulation of a variety of cellular functions. HIF-1α…”
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The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting IL-7 and CCL19 for Therapy of Refractory/Recurrent Multiple Myeloma by Duan, Deming, Wang, Keke, Wei, Cheng, Feng, Dudu, Liu, Yonghua, He, Qingyan, Xu, Xing, Wang, Chunling, Zhao, Shuping, Lv, Leili, Long, Jing, Lin, Danni, Zhao, Ai, Fang, Bingmu, Jiang, Jinhong, Tang, Shixing, Gao, Jimin

“…Chimeric antigen receptor (CAR) technology has revolutionized cancer treatment, particularly in malignant hematological tumors. Currently, the BCMA-targeted…”
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Norcantharidin enhances antitumor immunity of GM‐CSF prostate cancer cells vaccine by inducing apoptosis of regulatory T cells by Mo, Lijun, Zhang, Xinji, Shi, Xiaojun, Wei, Lili, Zheng, Dianpeng, Li, Hongwei, Gao, Jimin, Li, Jinlong, Hu, Zhiming

“…Norcantharidin (NCTD) is a promising antitumor drug with low toxicity. It was reported to be able to regulate immunity, but the mechanism is not yet clear…”
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Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells by Huang, Haishan, Zhu, Junlan, Li, Yang, Zhang, Liping, Gu, Jiayan, Xie, Qipeng, Jin, Honglei, Che, Xun, Li, Jingxia, Huang, Chao, Chen, Lung-Chi, Lyu, Jianxin, Gao, Jimin, Huang, Chuanshu

“…Chronic lung inflammation is accepted as being associated with the development of lung cancer caused by nickel exposure. Therefore, identifying the molecular…”
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Combination immunotherapy with interleukin‐2 surface‐modified tumor cell vaccine and programmed death receptor‐1 blockade against renal cell carcinoma by Zhang, Xinji, Shi, Xiaojun, Li, Jinlong, Hu, Zhiming, Gao, Jimin, Wu, Shihao, Long, Zhaolin

“…Immunotherapy may be an effective way to prevent postoperative recurrence of renal cell carcinoma. Streptavidin‐interleukin‐2 (SA‐IL‐2) surface‐modified tumor…”
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Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function by Shin, Jinwook, Wang, Shang, Deng, Wenhai, Wu, Jinhong, Gao, Jimin, Zhong, Xiao-Ping

“…The mechanisms that control invariant natural killer T (i NKT)-cell development and function are still poorly understood. The mechanistic or mammalian target…”
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PHLPP2 Downregulation Contributes to Lung Carcinogenesis Following B[a]P/B[a]PDE Exposure by Huang, Haishan, Pan, Xiaofu, Jin, Honglei, Li, Yang, Zhang, Lin, Yang, Caili, Liu, Pei, Liu, Ya, Chen, Lili, Li, Jingxia, Zhu, Junlan, Zeng, Xingruo, Fu, Kai, Chen, Guorong, Gao, Jimin, Huang, Chuanshu

“…The carcinogenic capacity of B[a]P/B[a]PDE is supported by epidemiologic studies. However, the molecular mechanisms responsible for B[a]P/B[a]PDE-caused lung…”
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Pattern Recognition Analysis of Proteins Using DNA-Decorated Catalytic Gold Nanoparticles by Yang, Xiafeng, Li, Jiang, Pei, Hao, Li, Di, Zhao, Yun, Gao, Jimin, Lu, Jianxin, Shi, Jiye, Fan, Chunhai, Huang, Qing

“…A label‐free protein analysis strategy is based on patterns of gold nanoparticle (AuNP) growth. AuNPs pretreated with different oligonucleotides are challenged…”
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Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly by Chen, Pengcheng, Deng, Wenhai, Li, Dandan, Zeng, Tai, Huang, Ling, Wang, Qun, Wang, Jinli, Zhang, Weiguang, Yu, Xiaoxiao, Duan, Deming, Wang, Jinle, Xia, Hong, Chen, Hanbin, Huang, Wesley, Li, Jingao, Zhang, Dahong, Zhong, Xiao-Ping, Gao, Jimin

“…Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such…”
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