Search Results - "Gao, Jian Rong"

Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity by Leventhal, Daniel S., Sokolovska, Anna, Li, Ning, Plescia, Christopher, Kolodziej, Starsha A., Gallant, Carey W., Christmas, Rudy, Gao, Jian-Rong, James, Michael J., Abin-Fuentes, Andres, Momin, Munira, Bergeron, Christopher, Fisher, Adam, Miller, Paul F., West, Kip A., Lora, Jose M.

“…Synthetic biology is a powerful tool to create therapeutics which can be rationally designed to enable unique and combinatorial functionalities. Here we…”
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Evaluating the coherence and time-domain profile of quantum cascade laser frequency combs by Burghoff, David, Yang, Yang, Hayton, Darren J, Gao, Jian-Rong, Reno, John L, Hu, Qing

“…Recently, much attention has been focused on the generation of optical frequency combs from quantum cascade lasers. We discuss how fast detectors can be used…”
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Enantioselective Arylative Dearomatization of Indoles via Pd-Catalyzed Intramolecular Reductive Heck Reactions by Shen, Chong, Liu, Ren-Rong, Fan, Ren-Jie, Li, Ying-Long, Xu, Teng-Fei, Gao, Jian-Rong, Jia, Yi-Xia

“…A highly enantioselective intramolecular arylative dearomatization of indoles via palladium-catalyzed reductive Heck reactions was developed. The new strategy…”
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Highly Enantioselective Construction of Trifluoromethylated All-Carbon Quaternary Stereocenters via Nickel-Catalyzed Friedel–Crafts Alkylation Reaction by Gao, Jian-Rong, Wu, Hao, Xiang, Bin, Yu, Wu-Bin, Han, Liang, Jia, Yi-Xia

“…A highly enantioselective Friedel–Crafts alkylation reaction of indoles with β-CF3-β-disubstituted nitroalkenes was achieved using a Ni(ClO4)2–bisoxazoline…”
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Engineered bacteria producing aryl‐hydrocarbon receptor agonists protect against ethanol‐induced liver disease in mice by Kouno, Tetsuya, Zeng, Suling, Wang, Yanhan, Duan, Yi, Lang, Sonja, Gao, Bei, Hartmann, Phillipp, Cabré, Noemí, Llorente, Cristina, Galbert, Chloé, Emond, Patrick, Sokol, Harry, James, Michael, Chao, Chun Cheih, Gao, Jian‐Rong, Perreault, Mylene, Hava, David L., Schnabl, Bernd

“…Background and Purpose Gut bacteria metabolize tryptophan into indoles. Intestinal levels of the tryptophan metabolite indole‐3‐acetic acid are reduced in…”
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Terahertz multiheterodyne spectroscopy using laser frequency combs by Yang, Yang, Burghoff, David, Hayton, Darren J., Gao, Jian-Rong, Reno, John L., Hu, Qing

“…The terahertz region is of great importance for spectroscopy since many molecules have absorption fingerprints there. Frequency combs based on terahertz…”
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Dual Catalysis for the Redox Annulation of Nitroalkynes with Indoles: Enantioselective Construction of Indolin-3-ones Bearing Quaternary Stereocenters by Liu, Ren-Rong, Ye, Shi-Chun, Lu, Chuan-Jun, Zhuang, Gui-Lin, Gao, Jian-Rong, Jia, Yi-Xia

“…The enantioselective redox annulation of nitroalkynes with indoles is enabled by gold/chiral phosphoric acid dual catalysis. A range of indolin‐3‐one…”
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An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria by Lubkowicz, David, Horvath, Nicholas G, James, Michael J, Cantarella, Pasquale, Renaud, Lauren, Bergeron, Christopher G, Shmueli, Ron B, Anderson, Cami, Gao, Jian‐Rong, Kurtz, Caroline B, Perreault, Mylene, Charbonneau, Mark R, Isabella, Vincent M, Hava, David L

“…Enteric hyperoxaluria (EH) is a metabolic disease caused by excessive absorption of dietary oxalate leading to the formation of chronic kidney stones and…”
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Ti/Au TES 32 × 32 Pixel Array: Uniformity, Thermal Crosstalk and Performance at Different X-Ray Energies by Taralli, Emanuele, D'Andrea, Matteo, Gottardi, Luciano, Nagayoshi, Kenishiro, Ridder, Marcel, de Wit, Martin, Visser, Sven, Vaccaro, Davide, Akamatsu, Hiroki, Ravensberg, Kevin, Hoogeveen, Ruud, Bruijn, Marcel, Gao, Jian-Rong

“…Large format arrays of transition edge sensor (TES) are crucial for the next generation of X-ray space observatories. Such arrays are required to achieve an…”
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Thermal Crosstalk of X-Ray Transition-Edge Sensor Micro-Calorimeters Under Frequency Domain Multiplexing Readout by Vaccaro, Davide, Akamatsu, Hiroki, Bruijn, Marcel, Gottardi, Luciano, den Hartog, Roland, van der Kuur, Jan, van der Linden, Ton, Nagayoshi, Kenishiro, Ravensberg, Kevin, Ridder, Marcel, Taralli, Emanuele, de Wit, Martin, Gao, Jian-Rong, Hoogeveen, Ruud, den Herder, Jan-Willem

“…We have measured and characterized the thermal crosstalk in two different arrays of transition-edge sensor (TES) X-ray microcalorimeters with frequency-domain…”
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Palladium-Catalyzed Three-Component Cascade Reaction: Facial Access to Densely Functionalized Indolizines by Liu, Ren-Rong, Lu, Chuan-Jun, Zhang, Ming-Di, Gao, Jian-Rong, Jia, Yi-Xia

“…A palladium‐catalyzed three‐component cascade reaction of 2‐(2‐enynyl)pyridines with nucleophiles and allyl halides has been developed, enabling the synthesis…”
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Single Pixel Performance of a 32 × 32 Ti/Au TES Array With Broadband X-Ray Spectra by D'Andrea, Matteo, Taralli, Emanuele, Akamatsu, Hiroki, Gottardi, Luciano, Nagayoshi, Kenichiro, Ravensberg, Kevin, Ridder, Marcel L., Vaccaro, Davide, de Vries, Cor P., de Wit, Martin, Bruijn, Marcel P., Hoogeveen, Ruud W. M., Gao, Jian-Rong

“…We are developing a kilo-pixels Ti/Au TES array as a backup option for Athena X-IFU. Here we report on single-pixel performance of a 32 × 32 array operated in…”
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Chiral phosphoric acid catalyzed asymmetric hydrogenolysis of racemic 3-aryl-3-hydroxyisoindolin-1-ones by Zhou, Jian-Qing, Sheng, Wei-Jian, Jia, Jian-Hong, Ye, Qing, Gao, Jian-Rong, Jia, Yi-Xia

“…The enantioselective hydrogenolysis of racemic 3-aryl-3-hydroxyisoindolin-1-ones catalyzed by BINOL-derived chiral phosphoric acid with benzothiazoline as the…”
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Nickel-Catalyzed Intramolecular Nucleophilic Addition of Aryl or Vinyl Chlorides to α-Ketoamides Through CCl Bond Activation by Hu, Jin-Xiu, Wu, Hao, Li, Chuan-Ying, Sheng, Wei-Jian, Jia, Yi-Xia, Gao, Jian-Rong

“…Nickeleophilic addition! The first example of a nickel‐catalyzed direct intramolecular nucleophilic addition of aryl or vinyl chlorides to α‐ketoamides through…”
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Noise Measurements of a Low-Noise Amplifier in the FDM Readout System for SAFARI by Wang, Qian, Audley, Michael D., Khosropanah, Pourya, van der Kuur, Jan, de Lange, Gert, Aminaei, Amin, Boersma, Dick, van der Tak, Floris, Gao, Jian-Rong

“…The SPICA-SAFARI instrument requires extremely sensitive transition edge sensor (TES) arrays with a noise equivalent power of 2 × 10 - 19 W/ Hz and a readout…”
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Sequential Cu(II)-promoted oxidation/[3 + 2] cycloaddition/aromatization tandem reaction for the synthesis of 2-substituted benzo[f]isoindole-4,9-dione by Lin, Zhang-qi, Li, Chao-dong, Su, Jun-yi, Niu, Wen-jie, Gao, Jian-rong, Li, Yu-jin

“…An efficient method for the synthesis of 2-substituted benzo[f]isoindole-4,9-dione derivatives from N-substituted iminodiacetates and quinones via a…”
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A novel GSK-3β inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway by Pang, Tao, Wang, Yun-jie, Gao, Yuan-xue, Xu, Yuan, Li, Qiu, Zhou, Yu-bo, Xu, Lei, Huang, Zhang-jian, Liao, Hong, Zhang, Lu-yong, Gao, Jian-rong, Ye, Qing, Li, Jia

“…Aim： To discover neuroprotective compounds and to characterize the discovered active compound YQ138 as a novel GSK-313 inhibitor. Methods： Primary rat…”
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Novel organic dye sensitizers containing fluorenyl and biphenyl moieties for solar cells by Xie, Yan, Han, Liang, Ge, Cheng-Sheng, Cui, Yan-Hong, Gao, Jian-Rong

“…Three novel triarylamine dyes（AFL1-AFL3） containing fluorenyl and the biphenyl moieties have been designed and synthesized for application in dye-sensitized…”
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Terahertz laser frequency combs by Burghoff, David, Kao, Tsung-Yu, Han, Ningren, Chan, Chun Wang Ivan, Cai, Xiaowei, Yang, Yang, Hayton, Darren J., Gao, Jian-Rong, Reno, John L., Hu, Qing

“…Terahertz light can be used to identify numerous complex molecules, but has traditionally remained unexploited due to the lack of powerful broadband sources…”
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Synthesis and fluorescence characteristics of selective ratiometric fluorescent sensors for silver ions based on 3-indolyl-4-indazolyl maleimide derivatives by Zhu, Bo-ye, Xu, Meng, Qian, Chun-xia, Han, Liang, Gao, Jian-rong, Ye, Qing, Li, Yu-Jin

“…Selective ratiometric fluorescent sensor b for detection of silver ions and its counterparts ( sensor a and c ) were efficiently synthesized based on…”
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