Search Results - "Gao, Jian"
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1
P-values - a chronic conundrum
Published in BMC medical research methodology (24-06-2020)“…In medical research and practice, the p-value is arguably the most often used statistic and yet it is widely misconstrued as the probability of the type I…”
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Epidemiology of alcoholic and nonalcoholic fatty liver disease in China
Published in Journal of gastroenterology and hepatology (01-08-2013)“…The prevalence of patients presenting with fatty liver disease (FLD) in China has approximately doubled over the past two decades. At present, FLD, which is…”
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3
Characteristics and Mechanism of Liver Injury in 2019 Coronavirus Disease
Published in Journal of clinical and translational hepatology (28-03-2020)“…An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (2019 coronavirus disease, COVID-19) since December 2019, from Wuhan,…”
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4
Mesenchymal stem cell-based drug delivery strategy: from cells to biomimetic
Published in Journal of controlled release (28-01-2019)“…Owing to the diversity and ease of preparation of nanomaterials, the rational nanocarriers with a rational design have become increasingly popular in medical…”
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5
New Trends on Obesity and NAFLD in Asia
Published in Journal of hepatology (01-10-2017)“…Abstract Traditionally, obesity and its related diseases are considered problems in Western countries. However, in the past two decades, urbanization in many…”
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Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota
Published in Scientific reports (08-05-2017)“…Non-alcoholic steatohepatitis (NASH) is an epidemic metabolic disease with limited therapeutic strategies. Cumulative data support the pivotal role of gut…”
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7
Exosomes as novel bio-carriers for gene and drug delivery
Published in International journal of pharmaceutics (15-04-2017)“…[Display omitted] Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic delivery systems. Recent studies have identified…”
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8
The global burden of liver disease: The major impact of China
Published in Hepatology (Baltimore, Md.) (01-12-2014)“…Liver disease is a major cause of illness and death worldwide. In China alone, liver diseases, primarily viral hepatitis (predominantly hepatitis B virus…”
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Editorial: changes of health‐related quality of life associated with liver disease severity and its improvement after treatment in NAFLD
Published in Alimentary pharmacology & therapeutics (01-01-2023)“…LINKED CONTENT This article is linked to Yilmaz et al papers. To view these articles, visit https://doi.org/10.1111/apt.17301 and…”
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Lipotoxic Hepatocyte‐Derived Exosomal MicroRNA 192‐5p Activates Macrophages Through Rictor/Akt/Forkhead Box Transcription Factor O1 Signaling in Nonalcoholic Fatty Liver Disease
Published in Hepatology (Baltimore, Md.) (01-08-2020)“…Background and Aims Hepatic macrophages can be activated by many factors such as gut‐derived bacterial components and factors released from damaged…”
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11
Microbial metabolites in non-alcoholic fatty liver disease
Published in World journal of gastroenterology : WJG (07-05-2019)“…The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising exponentially worldwide. The spectrum of NAFLD includes non-alcoholic fatty liver,…”
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12
Application of 3D cultured multicellular spheroid tumor models in tumor-targeted drug delivery system research
Published in Journal of controlled release (28-01-2018)“…Tumor-targeted drug delivery systems are promising for their advantages in enhanced tumor accumulation and reduced toxicity towards normal organs. However, few…”
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13
Evaluating the coherence and time-domain profile of quantum cascade laser frequency combs
Published in Optics express (26-01-2015)“…Recently, much attention has been focused on the generation of optical frequency combs from quantum cascade lasers. We discuss how fast detectors can be used…”
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14
The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease
Published in Hepatology international (01-12-2020)“…Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver disease and affects nearly a quarter of the global population. The…”
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15
A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement
Published in Journal of hepatology (01-07-2020)“…The exclusion of other chronic liver diseases including “excess” alcohol intake has until now been necessary to establish a diagnosis of metabolic…”
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16
Atomically Thin Mesoporous Nanomesh of Graphitic C3N4 for High-Efficiency Photocatalytic Hydrogen Evolution
Published in ACS nano (23-02-2016)“…Delamination of layer materials into two-dimensional single-atom sheets has induced exceptional physical properties, including large surface area, ultrahigh…”
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Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity
Published in Nature communications (01-06-2020)“…Synthetic biology is a powerful tool to create therapeutics which can be rationally designed to enable unique and combinatorial functionalities. Here we…”
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18
Tracking the evolutionary innovations of plant terrestrialization
Published in Gene (15-02-2021)“…•The mechanism of plant terrestrialization is crucial for understanding plant evolution.•The recent report of high-quality reference genomes of six species…”
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Epidemiology of non-alcoholic fatty liver disease in China
Published in Journal of hepatology (01-01-2009)“…Fatty liver (steatosis) is highly prevalent in China and is more often linked to obesity than to alcoholism. Among more affluent regions of China, the…”
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20
Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats
Published in Experimental & molecular medicine (10-09-2019)“…Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid…”
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