Search Results - "Gao, George F."
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From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens
Published in Cell (08-03-2018)“…100 years after the infamous “Spanish flu” pandemic, the 2017–2018 flu season has been severe, with numerous infections worldwide. In between, there have been…”
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Emerging H5N8 avian influenza viruses
Published in Science (American Association for the Advancement of Science) (21-05-2021)“…The global spread of H5N8 avian influenza viruses is a public health concern The first confirmed outbreak of highly pathogenic avian influenza virus (HPAIV) in…”
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MERS, SARS, and Ebola: The Role of Super-Spreaders in Infectious Disease
Published in Cell host & microbe (14-10-2015)“…Super-spreading occurs when a single patient infects a disproportionate number of contacts. The 2015 MERS-CoV, 2003 SARS-CoV, and to a lesser extent 2014–15…”
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A distinct name is needed for the new coronavirus
Published in The Lancet (British edition) (21-03-2020)Get full text
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Two-birds-one-stone approach to combine protein and mRNA vaccines for COVID-19
Published in Nature immunology (01-07-2023)“…COVID-19 vaccines have been successful, but their duration and level of protection could be improved to cover all SARS-CoV-2 variants. A self-assembling…”
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Influenza and the live poultry trade
Published in Science (American Association for the Advancement of Science) (18-04-2014)“…Live poultry trade at local markets has long been a part of China's national identity. From small villages to big cities, the gathering and selling of…”
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Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1
Published in Cell (14-01-2016)“…Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in humans and primates. Understanding how these viruses enter host cells could help to…”
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Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
Published in Nature communications (10-04-2017)“…The envelope spike (S) proteins of MERS-CoV and SARS-CoV determine the virus host tropism and entry into host cells, and constitute a promising target for the…”
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Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses
Published in Nature reviews. Microbiology (01-12-2014)“…Key Points Interspecies transmission of influenza A viruses is the result of many factors. One of the key factors involved is a shift in the receptor-binding…”
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Epidemiology, Evolution, and Pathogenesis of H7N9 Influenza Viruses in Five Epidemic Waves since 2013 in China
Published in Trends in microbiology (Regular ed.) (01-09-2017)“…H7N9 influenza viruses were first isolated in 2013 and continue to cause human infections. H7N9 infections represent an ongoing public health threat that has…”
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Receptor binding and complex structures of human ACE2 to spike RBD from omicron and delta SARS-CoV-2
Published in Cell (17-02-2022)“…The coronavirus disease 2019 (COVID-19) pandemic continues worldwide with many variants arising, some of which are variants of concern (VOCs). A recent VOC,…”
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Humoral and cellular immunity and the safety of COVID-19 vaccines: a summary of data published by 21 May 2021
Published in International immunology (01-10-2021)“…Abstract Coronavirus disease 2019 (COVID-19) has caused millions of deaths, and serious consequences to public health, economies and societies. Rapid responses…”
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Crystal Structure of the Capsid Protein from Zika Virus
Published in Journal of molecular biology (30-03-2018)“…Recently, Zika virus (ZIKV) emerged as a global public health concern and is distinct from other flaviviruses in many aspects, for example, causing…”
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A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS
Published in Cell (06-08-2020)“…Vaccines are urgently needed to control the ongoing pandemic COVID-19 and previously emerging MERS/SARS caused by coronavirus (CoV) infections. The CoV spike…”
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Inference of person-to-person transmission of COVID-19 reveals hidden super-spreading events during the early outbreak phase
Published in Nature communications (06-10-2020)“…Coronavirus disease 2019 (COVID-19) was first identified in late 2019 in Wuhan, Hubei Province, China and spread globally in months, sparking worldwide…”
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Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010
Published in The Lancet (British edition) (08-06-2013)“…Summary Background China has undergone rapid demographic and epidemiological changes in the past few decades, including striking declines in fertility and…”
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Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2
Published in Cell reports (Cambridge) (16-06-2020)“…The ongoing global pandemic of coronavirus disease 2019 (COVID-19) has caused a huge number of human deaths. Currently, there are no specific drugs or vaccines…”
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Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia
Published in The New England journal of medicine (26-03-2020)“…The authors provide an epidemiologic analysis of the first 425 confirmed cases of infection with the novel coronavirus in Wuhan, China. This analysis provides…”
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Epidemiology, Evolution, and Recent Outbreaks of Avian Influenza Virus in China
Published in Journal of virology (01-09-2015)“…Novel reassortants of H7N9, H10N8, and H5N6 avian influenza viruses (AIVs) are currently circulating in China's poultry flocks, occasionally infecting humans…”
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Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody
Published in Cell host & microbe (11-05-2016)“…Zika virus (ZIKV), a mosquito-borne flavivirus, is a current global public health concern. The flavivirus envelope (E) glycoprotein is responsible for virus…”
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