Search Results - "Gao, Daxin"
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Mechanical compression characteristics of rapeseed based on continuous damage theory
Published in Biosystems engineering (01-12-2022)“…In the process of mechanised sowing and harvesting, the damage and fragmentation of rapeseed are often caused by multiple contacts. The expansion of…”
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Development of a novel TLR8 agonist for cancer immunotherapy
Published in Molecular biomedicine (10-09-2020)“…Toll-like receptors (TLRs) are a family of proteins that recognize pathogen associated molecular patterns (PAMPs). Their primary function is to activate innate…”
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Correction to: Development of a novel TLR8 agonist for cancer immunotherapy
Published in Molecular biomedicine (21-05-2021)Get full text
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The effectiveness of high intensity laser therapy in the patients with lumbar disc herniation: A protocol of randomized placebo-controlled trial
Published in Medicine (Baltimore) (09-10-2020)“…There is no consensus in existing literature on the pulse power, application time, frequency and the dose of energy of laser therapy for the patients…”
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Syntheses of two diastereoisomers of panaxytriol, a potent antitumor agent isolated from panax ginseng
Published in Tetrahedron (04-06-1999)“…(3R, 9R, 10R) and (3R, 9S, 10S) diastereoisomers (2 and 3) of panaxytriol (1) were synthesized, and the absolute configuration of panaxytriol was confirmed as…”
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Synergetic effect of dual co-catalysts on the activity of BiVO4 for photocatalytic carbamazepine degradation
Published in RSC advances (2019)“…An efficient visible-light driven three components photocatalyst for carbamazepine (CBZ) degradation has been assembled by co-loading reduction cocatalyst Pt…”
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Synergetic effect of dual co-catalysts on the activity of BiVO 4 for photocatalytic carbamazepine degradation
Published in RSC advances (17-12-2019)“…An efficient visible-light driven three components photocatalyst for carbamazepine (CBZ) degradation has been assembled by co-loading reduction cocatalyst Pt…”
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Abstract 3655: Discovery of SC10914: a highly potent, selective and orally active PARP inhibitor for the treatment of BRCA1/2 deficient cancer
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract Poly(ADP ribose) polymerase (PARP) inhibitors are a class of anticancer agents that target DNA base excision repair and radio-sensitize cells through…”
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Abstract 2631: Discovery of SC110237, a highly potent, selective and orally active FLT3 inhibitor for the treatment of acute myeloid leukemia
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract FLT3 (Fms-like tyrosine kinase 3) is the most frequently mutated gene in acute myeloid leukemia (AML). Activating Flt3 mutations occur in about 30% of…”
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Abstract 3264: A novel TLR8 agonist induces immune responses and tumor regression
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Toll like receptors (TLRs) have been a recent focus of drug discovery for cancer immunotherapy. TLRs play a crucial role in bridging innate and…”
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Diosmetin reduces bone loss and osteoclastogenesis by regulating the expression of TRPV1 in osteoporosis rats
Published in Annals of translational medicine (01-10-2020)“…Osteoporosis is a systemic skeletal disorder and occurs frequently in postmenopausal women and older men. This study aimed to examine whether diosmetin (DIO)…”
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Abstract 2995: Development of a novel highly potent TLR8 selective agonist for cancer immunotherapy
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract The cancer drug discovery field is experiencing unprecedented revolution accompanied by growing excitement from researchers, drug developers, patients…”
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Abstract 3772: Preclinical study of a novel TLR8 selective agonist for cancer immunotherapy
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract The innate immune system has emerged as one of the major pathways for drug discovery focusing on cancer immunotherapy. TLR8 plays a crucial role in…”
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Synergetic effect of dual co-catalysts on the activity of BiVO for photocatalytic carbamazepine degradation
Published in RSC advances (17-12-2019)“…An efficient visible-light driven three components photocatalyst for carbamazepine (CBZ) degradation has been assembled by co-loading reduction cocatalyst Pt…”
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Abstract 5555: Discovery of DN-016: A highly potent, selective and orally available IDO1 inhibitor for treating cancers
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Indoleamine-2,3-dioxygenase (IDO1) is well-recognized as an important target for immunotherapeutic intervention. Growing interests on this target have…”
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Abstract 4877: Discovery of novel and potent inhibitors of indoleamine-2,3-dioxygenase (IDO1) for cancer immunotherapy
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Indoleamine-2,3-dioxygenase (IDO1) is an immune regulatory enzyme that oxidizes tryptophan to kynurenine. IDO1 is overexpressed in numerous tumor…”
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Synthesis and Biological Evaluation of Macrocyclized Betulin Derivatives as a Novel Class of Anti-HIV-1 Maturation Inhibitors
Published in The open medicinal chemistry journal (2014)“…A macrocycle provides diverse functionality and stereochemical complexity in a conformationally preorganized ring structure, and it occupies a unique chemical…”
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An Efficient Synthesis of Ring-Opening Metathesis Monomers and Polymers Containing Carbazole and Other Electron-Rich Moieties
Published in Advanced synthesis & catalysis (30-03-2001)“…An efficient synthesis of ring‐opening metathesis monomers and polymers containing ionizable moieties such as N‐carbazolyl, 2‐dibenzofuranyl,…”
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