Search Results - "Gao, Claire"
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The paraventricular nucleus of the thalamus: an integrative node underlying homeostatic behavior
Published in Trends in neurosciences (Regular ed.) (01-07-2021)“…Early anatomical evidence suggested that the paraventricular nucleus of the thalamus (PVT) regulates arousal, as well as emotional and motivated behaviors. We…”
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Two genetically, anatomically and functionally distinct cell types segregate across anteroposterior axis of paraventricular thalamus
Published in Nature neuroscience (01-02-2020)“…Unlike the sensory thalamus, studies on the functional organization of the midline and intralaminar nuclei are scarce, and this has hindered the establishment…”
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Expanded access with intravenous hydroxypropyl-β-cyclodextrin to treat children and young adults with Niemann-Pick disease type C1: a case report analysis
Published in Orphanet journal of rare diseases (21-10-2019)“…Niemann-Pick Disease Type C (NPC) is an inherited, often fatal neurovisceral lysosomal storage disease characterized by cholesterol accumulation in every cell…”
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Molecular and spatial profiling of the paraventricular nucleus of the thalamus
Published in eLife (03-03-2023)“…The paraventricular nucleus of the thalamus (PVT) is known to regulate various cognitive and behavioral processes. However, while functional diversity among…”
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Dissociable encoding of motivated behavior by parallel thalamo-striatal projections
Published in Current biology (08-04-2024)“…The successful pursuit of goals requires the coordinated execution and termination of actions that lead to positive outcomes. This process relies on…”
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CRISPR-Based Functional Transcriptomics Defines the Tumor-Dependency and Molecular Determinants of Long Noncoding RNAs in Multiple Myeloma
Published in Blood (02-11-2023)“…Long noncoding RNAs (lncRNAs) constitute most elements in the human transcriptome, yet we lack a comprehensive understanding of their role in tumor cells…”
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Identification of Parallel Functional Domains in the Paraventricular Nucleus of the Thalamus
Published in Biological psychiatry (1969) (01-05-2020)Get full text
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Two genetically, anatomically and functionally-distinct cell types segregate across the antero-posterior axis of the paraventricular thalamus
Published in Nature neuroscience (13-01-2020)“…Unlike sensory thalamus, studies on the functional organization of midline and intralaminar nuclei are scarce, and this has hampered the establishment of…”
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T81. EXCITATORY NEURONS IN HUMAN MEDIODORSAL THALAMUS ARE IMPLICATED IN GENETIC RISK FOR SERIOUS MENTAL ILLNESS
Published in European neuropsychopharmacology (01-10-2023)“…The mediodorsal thalamus (MDT) is critical for many executive functions, such as attention and working memory. Reduced structural and functional connectivity…”
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Expanded access with intravenous hydroxypropyl-[beta]-cyclodextrin to treat children and young adults with Niemann-Pick disease type C1: a case report analysis
Published in Orphanet journal of rare diseases (21-10-2019)“…Niemann-Pick Disease Type C (NPC) is an inherited, often fatal neurovisceral lysosomal storage disease characterized by cholesterol accumulation in every cell…”
Get full text
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Abstract P37: Decoding Cancer Dependency and Molecular Pathways of Long Noncoding RNAs with a Novel CRISPR-Cas13d Platform
Published in Blood cancer discovery (04-03-2024)“…Abstract Long noncoding RNAs (lncRNAs) constitute a significant portion of the human transcriptome, yet their precise role in tumor cells remains elusive. In…”
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