Search Results - "Gao, Chu"

Sepsis-induced immunosuppression: mechanisms, diagnosis and current treatment options by Liu, Di, Huang, Si-Yuan, Sun, Jian-Hui, Zhang, Hua-Cai, Cai, Qing-Li, Gao, Chu, Li, Li, Cao, Ju, Xu, Fang, Zhou, Yong, Guan, Cha-Xiang, Jin, Sheng-Wei, Deng, Jin, Fang, Xiang-Ming, Jiang, Jian-Xin, Zeng, Ling

“…Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to…”
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Targeting clock-controlled gene Nrf2 ameliorates inflammation-induced intervertebral disc degeneration by Peng, Pandi, Wang, Dong, Xu, Xiaolong, Wang, Di, Gao, Bo, Wang, Han, Jia, Haoruo, Shang, Qiliang, Zheng, Chao, Gao, Chu, Mao, Jianxin, Luo, Zhuojing, Yang, Liu, Hu, Xueyu

“…Background Intervertebral disc (IVD) is a highly rhythmic tissue, which experiences a diurnal cycle of high/low mechanical loading via the changes of…”
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DDA-SKF: Predicting Drug-Disease Associations Using Similarity Kernel Fusion by Gao, Chu-Qiao, Zhou, Yuan-Ke, Xin, Xiao-Hong, Min, Hui, Du, Pu-Feng

“…Drug repositioning provides a promising and efficient strategy to discover potential associations between drugs and diseases. Many systematic computational…”
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Shh Signaling from the Injured Lung Microenvironment Drives BMSCs Differentiation into Alveolar Type II Cells for Acute Lung Injury Treatment in Mice by Wu, Mengyu, Liu, Jing, Zhang, Shu, Jian, Yi, Guo, Ling, Zhang, Huacai, Mi, Junwei, Qu, Guoxin, Liu, Yaojun, Gao, Chu, Cai, Qingli, Wen, Dalin, Liu, Di, Sun, Jianhui, Jiang, Jianxin, Huang, Hong

“…Alveolar type II (AT2) cells are key effector cells for repairing damaged lungs. Direct differentiation into AT2 cells from bone marrow mesenchymal stem cells…”
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SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis by Mao, Jianxin, Wang, Di, Wang, Dong, Wu, Qi, Shang, Qiliang, Gao, Chu, Wang, Huanbo, Wang, Han, Du, Mu, Peng, Pandi, Jia, Haoruo, Xu, Xiaolong, Wang, Jie, Yang, Liu, Luo, Zhuojing

“…Mitochondrial dysfunction plays a major role in the development of intervertebral disc degeneration (IDD). Sirtuin 5 (SIRT5) participates in the maintenance of…”
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Numerical investigation on free air blast loads generated from center-initiated cylindrical charges with varied aspect ratio in arbitrary orientation by Gao, Chu, Kong, Xiang-zhen, Fang, Qin, Hong, Jian, Wang, Yin

“…In current guidelines, the free air blast loads (overpressure and impulse) are determined by spherical charges, although most of ordnance devices are more…”
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Role of Hedgehog Signaling Pathways in Multipotent Mesenchymal Stem Cells Differentiation by Wu, Mengyu, Mi, Junwei, Qu, Guo-Xin, Zhang, Shu, Jian, Yi, Gao, Chu, Cai, Qingli, Liu, Jing, Jiang, Jianxin, Huang, Hong

“…Multipotent mesenchymal stem cells (MSCs) have high self-renewal and multi-lineage differentiation potentials and low immunogenicity, so they have attracted…”
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A New Method for Programmable RNA Editing Using CRISPR Effector Cas13X.1 by Li, Luoxi, Liu, Wenyi, Zhang, Huacai, Cai, Qingli, Wen, Dalin, Du, Juan, Sun, Jianhui, Li, Li, Gao, Chu, Lin, Ping, Wu, Min, Jiang, Jianxin

“…Type VI CRISPR-Cas13 is the only CRISPR system that can bind and cleave RNA without DNase activity. We used the newly discovered, smaller Cas13X.1 protein to…”
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Post-synthetic modification of tryptophan containing peptides via NIS mediation by Gu, Chen-Xue, Bi, Qing-Wei, Gao, Chu-Kun, Wen, Jian, Zhao, Zhi-Gang, Chen, Zili

“…A new efficient method was developed to provide modified tryptophan peptides through NIS (N-iodosuccinimide) mediated N -selective coupling of a Trp unit with…”
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Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration by Wang, Dong, Peng, Pandi, Dudek, Michal, Hu, Xueyu, Xu, Xiaolong, Shang, Qiliang, Wang, Di, Jia, Haoruo, Wang, Han, Gao, Bo, Zheng, Chao, Mao, Jianxin, Gao, Chu, He, Xin, Cheng, Pengzhen, Wang, Huanbo, Zheng, Jianmin, Hoyland, Judith A, Meng, Qing-Jun, Luo, Zhuojing, Yang, Liu

“…The circadian clock participates in maintaining homeostasis in peripheral tissues, including intervertebral discs (IVDs). Abnormal mechanical loading is a…”
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An integrative model with HLA‐DR, CD64, and PD‐1 for the diagnostic and prognostic evaluation of sepsis by Chen, Guosheng, Chong, Huimin, Zhang, Peng, Wen, Dalin, Du, Juan, Gao, Chu, Zeng, Shi, Zeng, Ling, Deng, Jin, Zhang, Kejun, Zhang, Anqiang

“…Background Sepsis is a life‐threatening organ dysfunction caused by a dysregulated host response to infection and progressive immunosuppression with high…”
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Decoding the annulus fibrosus cell atlas by scRNA-seq to develop an inducible composite hydrogel: A novel strategy for disc reconstruction by Wang, Han, Wang, Di, Luo, Beier, Wang, Dong, Jia, Haoruo, Peng, Pandi, Shang, Qiliang, Mao, Jianxin, Gao, Chu, Peng, Ye, Gan, Lu, Du, Junjie, Luo, Zhuojing, Yang, Liu

“…Low back pain is one of the most serious public health problems worldwide and the major clinical manifestation of intervertebral disc degeneration (IVDD). The…”
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Facet joint degeneration—An initial procedure of the cervical spine degeneration by Shang, Qiliang, Wang, Dong, Wang, Di, Peng, Pandi, Wang, Han, Jia, Haoruo, Mao, Jianxin, Gao, Chu, Du, Mu, He, Xin, Ma, Yachao, Zheng, Chao, Yang, Liu, Luo, Zhuojing, Hu, Xueyu

“…Objective This study aims to emphasize the initiating role of facet joint (FJ) degeneration in the process of cervical spine degeneration induced by tangential…”
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Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities by Chu, Jung-Chun, Tseng, Hui-Ju, Lee, Sung-Bau, Hsu, Kai-Cheng, Hsin, Ling-Wei, Liang, Ru-Hao, Lin, Tony Eight, Gao, Nain-Chu, Chen, Liang-Chieh, Lu, Wan-Hsun, Wang, Andrew H.-J, Huang, Wei-Jan

“…Class II histone deacetylases (HDACs) are considered as potential targets to treat Alzheimer's disease (AD). Previously, C-3 substituted…”
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PDGFR kinase inhibitor protects against septic death via regulation of BTLA by Wang, Qiang, Deng, Jin, Sun, Jianhui, Zhang, Huacai, Liu, Di, Gao, Chu, Qiu, Jinchao, Liu, Wenyi, Qu, Guoxin, Wen, Dalin, Du, Juan, Zhang, Anqiang, Zeng, Ling, Jiang, Jianxin

“…Sepsis, defined as life-threatening organ failure caused by a dysregulated host response to severe infection, is a major cause of death among intensive care…”
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Tri-Band Dual-Polarization Shared-Aperture Microstrip Array for SAR Applications by ZHONG, Shun-Shi, ZHU SUN, KONG, Ling-Bing, CHU GAO, WEI WANG, JIN, Mou-Ping

“…The design of a tri-band dual-polarization (TBDP) shared-aperture microstrip array antenna for synthetic aperture radar (SAR) applications is presented. It…”
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Non-Gaussian Random Bi-matrix Models for Bi-free Central Limit Distributions with Positive Definite Covariance Matrices by Gao, Ming Chu

“…In this paper, we construct random two-faced families of matrices with non-Gaussian entries to approximate a bi-free central limit distribution with a positive…”
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A Study on the Impact of Chemical Structure on the Evolution of Aggregate Structure in Fiber-shaped High Density Polyethylene Vitrimer by Wang, Bing, Gao, Yuan-Chu, Wang, Hai, Niu, Hui

“…Vitrimers have emerged as a prominent research area in the field of polymer materials. Most of the studies have focused on synthesizing polymers with versatile…”
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Nuclear magnetic resonance analysis of freeze-thaw damage in natural pumice concrete by Wang, Xiaoxiao, Shen, Xiangdong, Wang, Hailong, Gao, Chu, Zhang, Tong

“…This paper presents an analysis of the damage propagation features of the pore structure of natural pumice lightweight aggregate concrete (LWC) under…”
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Identification of novel genes associated with duck OASL in response to influenza A virus by WANG, Xiao-xue, LU, Chang, RONG, En-guang, HU, Jia-xiang, XING, Yan-ling, LIU, Zheng-yu, GAO, Chu-ze, LIU, Jin-hua, HUANG, Yin-hua

“…2'-5'-Oligoadenylate synthetase like protein (OASL) plays a key role in response to viral infections through selectively activating the OAS/RNase L or…”
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