Search Results - "Gao, Cai‐Yue"

Tissue‐Resident Memory CD8+ T Cells Acting as Mediators of Salivary Gland Damage in a Murine Model of Sjögren's Syndrome by Gao, Cai‐Yue, Yao, Yuan, Li, Liang, Yang, Shu‐Han, Chu, Hui, Tsuneyama, Koichi, Li, Xiao‐Mei, Gershwin, M. Eric, Lian, Zhe‐Xiong

“…Objective Although a role for CD4+ T cells in the pathogenesis of Sjögren's syndrome (SS) has been documented, the pathogenic significance of CD8+ T cells is…”
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Restriction on molecular fluxionality by substitution: A case study for the 1,10‐dicyanobullvalene by Pei, Bin‐Bin, Yang, Hongjuan, Gao, Cai‐Yue, Man, Yuan, Yang, Yonggang, Li, Si‐Dian

“…We show herein that 1,10‐dicyano substitution restricts the paragon fluxionality of bullvalene to just 14 isomers which isomerize along a single cycle. The…”
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Cl©Li5Cl5−: A Star-like Superhalogen Anion Featuring a Planar Pentacoordinate Chlorine at the Center by Bai, Li-Xia, Gao, Cai-Yue, Guo, Jin-Chang, Li, Si-Dian

“…Among the known planar pentacoordinate atoms, chlorine is missing due to its large radius and high electronegativity. Herein, we report the first star-like…”
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Immunobiology of T Cells in Sjögren’s Syndrome by Yao, Yuan, Ma, Jin-Fen, Chang, Christopher, Xu, Ting, Gao, Cai-Yue, Gershwin, M. Eric, Lian, Zhe-Xiong

“…Sjögren’s syndrome (SjS) is a systemic autoimmune disease marked by xerostomia (dry mouth), keratoconjunctivitis sicca (eye dryness), and other systematic…”
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Targeting pathogenic CD8+ tissue-resident T cells with chimeric antigen receptor therapy in murine autoimmune cholangitis by Zhu, Hao-Xian, Yang, Shu-Han, Gao, Cai-Yue, Bian, Zhen-Hua, Chen, Xiao-Min, Huang, Rong-Rong, Meng, Qian-Li, Li, Xin, Jin, Haosheng, Tsuneyama, Koichi, Han, Ying, Li, Liang, Zhao, Zhi-Bin, Gershwin, M. Eric, Lian, Zhe-Xiong

“…Primary biliary cholangitis (PBC) is a cholestatic autoimmune liver disease characterized by autoreactive T cell response against intrahepatic small bile…”
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Gut microbiota translocation promotes autoimmune cholangitis by Ma, Hong-Di, Zhao, Zhi-Bin, Ma, Wen-Tao, Liu, Qing-Zhi, Gao, Cai-Yue, Li, Liang, Wang, Jinjun, Tsuneyama, Koichi, Liu, Bin, Zhang, Weici, Zhou, Yongjian, Gershwin, M. Eric, Lian, Zhe-Xiong

“…Gut microbiota and bacterial translocation have been implicated as significant contributors to mucosal immune responses and tolerance; alteration of microbial…”
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Chromatin accessibility analysis identifies the transcription factor ETV5 as a suppressor of adipose tissue macrophage activation in obesity by Hu, Ren-Dong, Zhang, Wen, Li, Liang, Zuo, Zu-Qi, Ma, Min, Ma, Jin-Fen, Yin, Ting-Ting, Gao, Cai-Yue, Yang, Shu-Han, Zhao, Zhi-Bin, Li, Zi-Jun, Qiao, Gui-Bin, Lian, Zhe-Xiong, Qu, Kun

“…Activation of adipose tissue macrophages (ATMs) contributes to chronic inflammation and insulin resistance in obesity. However, the transcriptional regulatory…”
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Multi-Omics Profiling Identifies Pathways Associated With CD8 + T-Cell Activation in Severe Aplastic Anemia by You, Xing, Yang, Qiong, Yan, Kai, Wang, Song-Rong, Huang, Rong-Rong, Wang, Shun-Qing, Gao, Cai-Yue, Li, Liang, Lian, Zhe-Xiong

“…Severe aplastic anemia (SAA) is an autoimmune disease characterized by immune-mediated destruction of hematopoietic stem and progenitor cells. Autoreactive CD8…”
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IFN-γ-STAT1-iNOS Induces Myeloid Progenitors to Acquire Immunosuppressive Activity by Yang, Shu-Han, Li, Liang, Xie, Yu-Qing, Yao, Yuan, Gao, Cai-Yue, Liao, Liang-Huan, Ma, Hong-Di, Gershwin, M Eric, Lian, Zhe-Xiong

“…Autoimmune diseases often induce dysregulated hematopoiesis with altered number and function of hematopoietic stem and progenitor cells (HSPCs). However, there…”
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Fluxional halogen bonds in linear complexes of tetrafluorodiiodobenzene with dinitrobenzene by Gao, Cai-Yue, Pei, Bin-Bin, Li, Si-Dian

“…The fluxional nature of halogen bonds (XBs) in small molecular clusters, supramolecules, and molecular crystals has received considerable attention in recent…”
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Fluxional Hydrogen Bonds in Small Water Clusters (H2O)n (n = 2–6) by Gao, Cai-Yue, Ma, Yuan-Yuan, Chen, Qiang, Li, Si-Dian

“…Understanding the fluxional bonding nature of hydrogen bonds (HBs) and their networks in small water clusters and bulk water remains a huge challenge in both…”
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Cage-like La4B24 and Core-Shell La4B290/+/− : perfect spherically aromatic tetrahedral metallo-borospherenes by Lu, Xiao-Qin, Gao, Cai-Yue, Wei, Zhihong, Li, Si-Dian

“…Cage-like and core-shell metallo-borospherenes exhibit interesting structures and bonding. Based on extensive global searches and first-principles theory…”
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Perfect Tetrahedral B16X4 (X = P, As) as Non-metal-stabilized Borospherenes with a Truncated B16 Cage at the Center by Gao, Cai-Yue, Yan, Qiao-Qiao, Chen, Qiang, Mu, Yue-Wen, Li, Si-Dian

“…Based on extensive global minimum searches augmented with first-principles theory calculations, we predict herein the first boron-based perfect tetrahedral…”
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Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming by Yan, Kai, Da, Tian-Tian, Bian, Zhen-Hua, He, Yi, Liu, Meng-Chu, Liu, Qing-Zhi, Long, Jie, Li, Liang, Gao, Cai-Yue, Yang, Shu-Han, Zhao, Zhi-Bin, Lian, Zhe-Xiong

“…Macrophages are plastic cells that can switch among different states according to bioenergetic or biosynthetic requirements. Our previous work demonstrated…”
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Increased proportion of follicular helper T cells is associated with B cell activation and disease severity in IgA nephropathy by Du, Wanshan, Gao, Cai-Yue, You, Xing, Li, Liang, Zhao, Zhi-Bin, Fang, Mengting, Ye, Zhiming, Si, Meijun, Lian, Zhe-Xiong, Yu, Xueqing

“…IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by glomerular deposition of IgA immune complexes, mainly produced by B…”
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The molecular basis of immune regulation in autoimmunity by Yang, Shu-Han, Gao, Cai-Yue, Li, Liang, Chang, Christopher, Leung, Patrick S C, Gershwin, M Eric, Lian, Zhe-Xiong

“…Autoimmune diseases can be triggered and modulated by various molecular and cellular characteristics. The mechanisms of autoimmunity and the pathogenesis of…”
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CD8+ T cells and IFN-γ induce autoimmune myelofibrosis in mice by Yao, Yuan, Li, Liang, Yang, Shu-Han, Gao, Cai-Yue, Liao, Liang-Huan, Xie, Yu-Qing, Yin, Xue-Ying, Yang, Yan-Qing, Fei, Yun-Yun, Lian, Zhe-Xiong

“…Myelofibrosis usually occurs either as a part of a myelodysplastic syndrome or in conjunction with neoplasia. It is not commonly thought of an autoimmune…”
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Single-cell profiling reveals pathogenic role and differentiation trajectory of granzyme K+CD8+ T cells in primary Sjögren's syndrome by Xu, Ting, Zhu, Hao-Xian, You, Xing, Ma, Jin-Fen, Li, Xin, Luo, Pan-Yue, Li, Yang, Lian, Zhe-Xiong, Gao, Cai-Yue

“…Primary Sjögren's syndrome (pSS) is a systemic autoimmune inflammatory disease mainly defined by T cell-dominated destruction of exocrine glands. Currently,…”
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Cl©Li 5 Cl 5 - : A Star-like Superhalogen Anion Featuring a Planar Pentacoordinate Chlorine at the Center by Bai, Li-Xia, Gao, Cai-Yue, Guo, Jin-Chang, Li, Si-Dian

“…Among the known planar pentacoordinate atoms, chlorine is missing due to its large radius and high electronegativity. Herein, we report the first star-like…”
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Tissue‐Resident Memory CD 8+ T Cells Acting as Mediators of Salivary Gland Damage in a Murine Model of Sjögren's Syndrome by Gao, Cai‐Yue, Yao, Yuan, Li, Liang, Yang, Shu‐Han, Chu, Hui, Tsuneyama, Koichi, Li, Xiao‐Mei, Gershwin, M. Eric, Lian, Zhe‐Xiong

“…Objective Although a role for CD 4+ T cells in the pathogenesis of Sjögren's syndrome ( SS ) has been documented, the pathogenic significance of CD 8+ T cells…”
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