Search Results - "Ganz, Peter"

Role of endothelial dysfunction in atherosclerosis by Davignon, Jean, Ganz, Peter

“…As the major regulator of vascular homeostasis, the endothelium exerts a number of vasoprotective effects, such as vasodilation, suppression of smooth muscle…”
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Plasma protein patterns as comprehensive indicators of health by Williams, Stephen A., Kivimaki, Mika, Langenberg, Claudia, Hingorani, Aroon D., Casas, J. P., Bouchard, Claude, Jonasson, Christian, Sarzynski, Mark A., Shipley, Martin J., Alexander, Leigh, Ash, Jessica, Bauer, Tim, Chadwick, Jessica, Datta, Gargi, DeLisle, Robert Kirk, Hagar, Yolanda, Hinterberg, Michael, Ostroff, Rachel, Weiss, Sophie, Ganz, Peter, Wareham, Nicholas J.

“…Proteins are effector molecules that mediate the functions of genes 1 , 2 and modulate comorbidities 3 – 10 , behaviors and drug treatments 11 . They represent…”
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Mechanisms of Sodium-Glucose Cotransporter 2 Inhibition: Insights From Large-Scale Proteomics by Ferrannini, Ele, Murthy, Ashwin C, Lee, Yong-Ho, Muscelli, Elza, Weiss, Sophie, Ostroff, Rachel M, Sattar, Naveed, Williams, Stephen A, Ganz, Peter

“…To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics…”
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Behavioral Cardiovascular Risk Factors　– Effect of Physical Activity and Cardiorespiratory Fitness on Cardiovascular Outcomes by Spencer, Rachel M., Heidecker, Bettina, Ganz, Peter

“…Primary and primordial prevention of cardiovascular disease (CVD) requires not only identification of risk factors, but also appropriate and timely therapy. In…”
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The Princeton III Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease by Nehra, Ajay, MD, Jackson, Graham, FRCP, FESC, Miner, Martin, MD, Billups, Kevin L., MD, Burnett, Arthur L., MD, MBA, Buvat, Jacques, MD, Carson, Culley C., MD, Cunningham, Glenn R., MD, Ganz, Peter, MD, Goldstein, Irwin, MD, Guay, Andre T., MD, Hackett, Geoff, MD, Kloner, Robert A., MD, PhD, Kostis, John, MD, Montorsi, Piero, MD, Ramsey, Melinda, PhD, Rosen, Raymond, PhD, Sadovsky, Richard, MD, Seftel, Allen D., MD, Shabsigh, Ridwan, MD, Vlachopoulos, Charalambos, MD, Wu, Frederick C.W., MD

“…Abstract The Princeton Consensus (Expert Panel) Conference is a multispecialty collaborative tradition dedicated to optimizing sexual function and preserving…”
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Role of nitric oxide in the regulation of digital pulse volume amplitude in humans by Nohria, Anju, Gerhard-Herman, Marie, Creager, Mark A, Hurley, Shauna, Mitra, Debi, Ganz, Peter

“…Cardiovascular Division, Brigham and Women's Hospital, Boston, Massachusetts Submitted 6 October 2005 ; accepted in final form 11 April 2006 Measurement of the…”
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Evaluation of a large-scale aptamer proteomics platform among patients with kidney failure on dialysis by Ren, Yue, Ruan, Peifeng, Segal, Mark, Dobre, Mirela, Schelling, Jeffrey R, Banerjee, Upasana, Shafi, Tariq, Ganz, Peter, Dubin, Ruth F

“…Patients with kidney failure suffer high mortality, and we currently lack markers for risk stratification for these patients. We carried out a quality control…”
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Role of viral replication, antiretroviral therapy, and immunodeficiency in HIV-associated atherosclerosis by HSUE, Priscilla Y, HUNT, Peter W, SCHNELL, Amanda, KALAPUS, S. Craig, HOH, Rebecca, GANZ, Peter, MARTIN, Jeffrey N, DEEKS, Steven G

“…HIV-seropositive patients are at higher risk for atherosclerosis than HIV-seronegative persons. This has been variably attributed to antiretroviral drug…”
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Does Erectile Dysfunction Contribute to Cardiovascular Disease Risk Prediction Beyond the Framingham Risk Score? by Araujo, Andre B., PhD, Hall, Susan A., PhD, Ganz, Peter, MD, Chiu, Gretchen R., MS, Rosen, Raymond C., PhD, Kupelian, Varant, PhD, Travison, Thomas G., PhD, McKinlay, John B., PhD

“…Objectives This study was designed to determine whether erectile dysfunction (ED) predicts cardiovascular disease (CVD) beyond traditional risk factors…”
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Rheumatoid Arthritis: A Model of Systemic Inflammation Driving Atherosclerosis by Ku, Ivy A., Imboden, John B., Hsue, Priscilla Y., Ganz, Peter

“…Similarities between the inflammatory pathways in atherosclerosis and rheumatoid arthritis (RA) are striking. Chronic systemic inflammation in RA patients…”
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Proteomic analysis of heart failure hospitalization among patients with chronic kidney disease: The Heart and Soul Study by Dubin, Ruth F, Whooley, Mary, Pico, Alexander, Ganz, Peter, Schiller, Nelson B, Meyer, Craig

“…Patients with chronic kidney disease (CKD) are at increased risk for heart failure (HF). We aimed to investigate differences in proteins associated with HF…”
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Proteomics of CKD progression in the chronic renal insufficiency cohort by Dubin, Ruth F., Deo, Rajat, Ren, Yue, Wang, Jianqiao, Zheng, Zihe, Shou, Haochang, Go, Alan S., Parsa, Afshin, Lash, James P., Rahman, Mahboob, Hsu, Chi-yuan, Weir, Matthew R., Chen, Jing, Anderson, Amanda, Grams, Morgan E., Surapaneni, Aditya, Coresh, Josef, Li, Hongzhe, Kimmel, Paul L., Vasan, Ramachandran S., Feldman, Harold, Segal, Mark R., Ganz, Peter

“…Progression of chronic kidney disease (CKD) portends myriad complications, including kidney failure. In this study, we analyze associations of 4638 plasma…”
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Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease by Nissen, Steven E, Tuzcu, E. Murat, Schoenhagen, Paul, Crowe, Tim, Sasiela, William J, Tsai, John, Orazem, John, Magorien, Raymond D, O'Shaughnessy, Charles, Ganz, Peter

“…Statins have pleiotropic effects, reducing not only low-density lipoprotein cholesterol levels, but also the levels of C-reactive protein (CRP), an…”
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Proteomics for heart failure risk stratification: a systematic review by Kuku, Kayode O, Oyetoro, Rebecca, Hashemian, Maryam, Livinski, Alicia A, Shearer, Joseph J, Joo, Jungnam, Psaty, Bruce M, Levy, Daniel, Ganz, Peter, Roger, Véronique L

“…Heart failure (HF) is a complex clinical syndrome with persistently high mortality. High-throughput proteomic technologies offer new opportunities to improve…”
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Right Ventricular Dysfunction Assessed by Cardiovascular Magnetic Resonance Imaging Predicts Poor Prognosis Late After Myocardial Infarction by Larose, Eric, DVM, MD, Ganz, Peter, MD, Reynolds, H. Glenn, MSc, Dorbala, Sharmila, MD, Di Carli, Marcelo F., MD, Brown, Kenneth A., MD, Kwong, Raymond Y., MD, MPH

“…Right Ventricular Dysfunction Assessed by Cardiovascular Magnetic Resonance Imaging Predicts Poor Prognosis Late After Myocardial Infarction Eric Larose, Peter…”
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The CHADS2 score predicts ischemic stroke in the absence of atrial fibrillation among subjects with coronary heart disease: Data from the Heart and Soul Study by Welles, Christine C., MD, Whooley, Mary A., MD, Na, Beeya, MPH, Ganz, Peter, MD, Schiller, Nelson B., MD, Turakhia, Mintu P., MD, MAS

“…Background We sought to evaluate the prognostic performance of the CHADS2 score for prediction of ischemic stroke/transient ischemic attack (TIA) in subjects…”
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Identification of Protein Biomarkers of the Dietary Approaches to Stop Hypertension Diet in Randomized Feeding Studies and Validation in an Observational Study by Kim, Hyunju, Lichtenstein, Alice H, Ganz, Peter, Du, Shutong, Tang, Olive, Yu, Bing, Chatterjee, Nilanjan, Appel, Lawrence J, Coresh, Josef, Rebholz, Casey M

“…Background The Dietary Approaches to Stop Hypertension (DASH) diet is recommended for cardiovascular disease prevention. We aimed to identify protein…”
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Impact of Kidney Function on the Blood Proteome and on Protein Cardiovascular Risk Biomarkers in Patients With Stable Coronary Heart Disease by Yang, Joseph, Brody, Edward N, Murthy, Ashwin C, Mehler, Robert E, Weiss, Sophie J, DeLisle, Robert K, Ostroff, Rachel, Williams, Stephen A, Ganz, Peter

“…Background Chronic kidney disease (CKD) confers increased cardiovascular risk, not fully explained by traditional factors. Proteins regulate biological…”
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Role of T‐Cell Dysfunction, Inflammation, and Coagulation in Microvascular Disease in HIV by Sinha, Arjun, Ma, Yifei, Scherzer, Rebecca, Hur, Sophia, Li, Danny, Ganz, Peter, Deeks, Steven G., Hsue, Priscilla Y.

“…Background Compared to uninfected adults, HIV‐infected adults on antiretroviral therapy are at increased risk of cardiovascular disease. Given the increase in…”
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Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients by HSUE, Priscilla Y, HUNT, Peter W, WU, Yuaner, SCHNELL, Amanda, HO, Jennifer E, HATANO, Hiroyu, YU XIE, MARTIN, Jeffrey N, GANZ, Peter, DEEKS, Steven G

“…HIV-infected patients have accelerated atherosclerosis. Abacavir has been associated with increased risk of cardiovascular events, for reasons that remain to…”
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