Search Results - "Ganoza, M C"

The Oxazolidinone Linezolid Inhibits Initiation of Protein Synthesis in Bacteria by SWANEY, S. M, AOKI, H, GANOZA, M. C, SHINABARGER, D. L

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Molecular localization of a ribosome-dependent ATPase on Escherichia coli ribosomes by Xu, J., Kiel, M. C., Golshani, A., Chosay, J. G., Aoki, H., Ganoza, M. C.

“…We have previously isolated and described an Escherichia coli ribosome-bound ATPase, RbbA, that is required for protein synthesis in the presence of ATP, GTP…”
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Peptide bond synthesis: function of the efp gene product by Ganoza, M C, Aoki, H

“…The efp gene encodes a protein that is essential for the growth and for the viability of Escherichia coli cells. Interruption of this gene results in cell…”
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A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes by GANOZA, M. Clelia, KIEL, Michael C

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Molecular characterization of the prokaryotic efp gene product involved in a peptidyltransferase reaction by Aoki, H., Adams, S.L., Turner, M.A., Ganoza, M.C.

“…The translation factor EF-P is required for efficient prokaryotic peptide bond synthesis on 70S ribosomes from fMet-tRNA f Met. This protein has been purified…”
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Oxazolidinone Antibiotics Target the P Site on Escherichia coli Ribosomes by AOKI, Hiroyuki, LIZHU KE, POPPE, Susan M, POEL, Toni J, WEAVER, Elizabeth A, GADWOOD, Robert C, THOMAS, Richard C, SHINABARGER, Dean L, GANOZA, M. Clelia

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Evolutionary Conservation of Reactions in Translation by GANOZA, M. Clelia, KIEL, Michael C, AOKI, Hiroyuki

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The ribosome as ‘affinity matrix’: Efficient purification scheme for translation factors by Ganoza, M.C., Aoki, H., Burkhardt, N., Murphy, B.J.

“…A convenient method to purify each of the non-ribosomal proteins required to translate a native mRNA in vitro is described. In this scheme, the ribosome is…”
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Potential secondary structure at the translational start domain of eukaryotic and prokaryotic mRNAs by Ganoza, M C, Louis, B G

“…In order to identify conserved potential secondary structures within translational start sites, mRNA sequences derived from different species were studied with…”
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Potential secondary structure at translation-initiation sites by GANOZA, M. C, KOFOID, E. C, LOUIS, B. G

“…Since translational start codons also occur internally, more-complex features within mRNA must determine initiation. We compare the potential secondary…”
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Isolation and Point of Action of a Factor from Escherichia coli Required to Reconstruct Translation by Ganoza, M. Clelia, Cunningham, Christina, Green, Robert M.

“…To study the mechanism of translation we have attempted to reconstruct the process from purified components. Protein synthesis was programmed by the RNAs of…”
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Initiator tRNA May Recognize More Than the Initiation Codon in mRNA: A Model for Translational Initiation by Ganoza, M. C., Marliere, P., Kofoid, E. C., Louis, B. G.

“…A special methionine tRNA (tRNAi) is universally required to initiate translation. Amongst species a tRNAistructural conservation is most apparent in the…”
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Effect of deletions 5' to the translation initiation sequence on the expression of an mRNA in animal cells by GANOZA, M. C, FARROW, N. A, AN, G

“…To learn if an mRNA.18S rRNA interaction or a special secondary structure in the mRNA start region is essential for translation in eukaryotic cells, we…”
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Protected nucleotide G2608 in 23S rRNA confers resistance to oxazolidinones in E. coli by Xu, Jianhua, Golshani, Ashkan, Aoki, Hiroyuki, Remme, Jaanus, Chosay, John, Shinabarger, Dean L., Ganoza, M. Clelia

“…The oxazolidinones are a new class of potent antibiotics that are active against a broad spectrum of Gram-positive bacterial pathogens including those…”
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A proposed role for IF-3 and EF-T in maintaining the specificity of prokaryotic initiation complex formation by GANOZA, M. C, CUNNINGHAM, C, CHUNG, D. G, NEILSON, T

“…Initiation factor-free 30S subunits of E. coli ribosomes bind aminoacyl-tRNAs more efficiently than fMet-tRNA(fMet). Elongator-tRNA binding was unaffected by…”
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Identification of a Soluble Protein that Stimulates Peptide Bond Synthesis by Glick, Bernard R., Ganoza, M. Clelia

“…A soluble protein factor was isolated, free of elongation factor (EF)-T and EF-G, based on its ability to stimulate the synthesis of peptide bonds using…”
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Signals determining translational start-site recognition in eukaryotes and their role in prediction of genetic reading frames by LOUIS, B. G, GANOZA, M. C

“…A special methionyl-tRNA (RNAi) is universally required to initiate translation. The conversation of this reactant throughout evolution, as well as its unusual…”
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The Gene Encoding the Elongation Factor P Protein Is Essential for Viability and Is Required for Protein Synthesis by Aoki, Hiroyuki, Dekany, Katalin, Adams, Sally-Lin, Ganoza, M. Clelia

“…Elongation factor P (EFP) is a protein that stimulates the peptidyltransferase activity of fully assembled 70 S prokaryotic ribosomes and enhances the…”
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Molecular characterization of a prokaryotic translation factor homologous to the eukaryotic initiation factor eIF4A by Lu, Jie, Aoki, Hiroyuki, Ganoza, M.Clelia

“…Initiation of translation involves a complex series of reactions that result in the formation of an initiation complex at the proper start site of the mRNA…”
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Requirements for in vitro reconstruction of protein synthesis by Green, R H, Glick, B R, Ganoza, M C

“…Translation of f2am3 RNA and MS2 RNA in a system containing purified ribosomes and precharged aminoacyl-tRNA, does not occur in the presence of the "known"…”
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