Search Results - "Gannu, Ramesh"
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Transmucosal delivery of domperidone from bilayered buccal patches: In Vitro, Ex Vivo and In Vivo characterization
Published in Archives of pharmacal research (01-10-2011)“…Bilayered mucoadhesive buccal patches for systemic administration of domperidone (DOM), a dopamine-receptor (D 2 ) antagonist, were developed using hydroxy…”
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Effect of Pomegranate Juice on Intestinal Transport and Pharmacokinetics of Nitrendipine in Rats
Published in Phytotherapy research (01-08-2012)“…Pomegranate juice (PJ) is known to be a potent inhibitor of human cytochromes (CYP), particularly CYP2C9 and CYP3A4. The purpose of this study was to…”
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Transdermal therapeutic system of isradipine: Effect of hydrophilic and hydrophobic matrix on In Vitro and Ex vivo characteristics
Published in Archives of pharmacal research (01-07-2010)“…Isradipine (ISDP) is an effective calcium channel blocker used in the treatment of hypertension. It undergoes extensive first pass metabolism and…”
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Development of nitrendipine transdermal patches: in vitro and ex vivo characterization
Published in Current drug delivery (01-01-2007)“…The aim of the investigation was to develop and evaluate matrix type transdermal drug delivery systems (TDDS) of nitrendipine (NTDP). The matrix type TDDS of…”
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Development of a high-performance liquid chromatography method for simultaneous determination of pioglitazone and felodipine in pig serum: application to pharmacokinetic study
Published in Biomedical chromatography (01-08-2011)“…A simple and sensitive high‐performance liquid chromatographic method was developed and validated for simultaneous estimation of pioglitazone and felodipine in…”
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Development of high performance liquid chromatography method for lacidipine in rabbit serum: Application to pharmacokinetic study
Published in Analytica chimica acta (26-01-2009)“…A simple and sensitive high performance liquid chromatographic (HPLC) method for quantification of lacidipine (LCDP) in rabbit serum was developed and…”
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Development of high performance liquid chromatography method for buspirone in rabbit serum: Application to pharmacokinetic study
Published in Analytica chimica acta (11-08-2009)“…A simple and sensitive high performance liquid chromatographic (HPLC) method for quantification of buspirone (BUSP) in rabbit serum was developed and…”
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Enhanced bioavailability of lacidipine via microemulsion based transdermal gels: Formulation optimization, ex vivo and in vivo characterization
Published in International journal of pharmaceutics (30-03-2010)“…The purpose of the present study was to develop and optimize the microemulsion based transdermal therapeutic system for lacidipine (LCDP), a poorly water…”
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Development of an In Vitro-In Vivo Correlation for Sitagliptin and Metformin Prolonged-release Tablet Formulations
Published in Turkish journal of pharmaceutical sciences (20-04-2021)“…The objective of this study was to establish and validate an correlation (IVIVC). To investigate the safety of a fixed-dose combination (FDC) versus the…”
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Development and Optimization of a Novel Prolonged Release Formulation to Resist Alcohol-Induced Dose Dumping
Published in AAPS PharmSciTech (01-04-2016)“…Alcohol-induced dose dumping is a serious concern for the orally administered prolonged release dosage forms. The study was designed to optimize the…”
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Oral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology
Published in Pharmaceutical development and technology (01-02-2013)“…The objective of the study was to prepare and characterize the domperidone (DOM) hot-melt extruded (HME) buccal films by both in vitro and in vivo techniques…”
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12
Optimization of Hydrogels for Transdermal Delivery of Lisinopril by Box–Behnken Statistical Design
Published in AAPS PharmSciTech (2009)“…The aim of this study was to investigate the combined influence of three independent variables on the permeation kinetics of lisinopril from hydrogels for…”
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13
Formulation Optimization and Evaluation of Microemulsion Based Transdermal Therapeutic System for Nitrendipine
Published in Journal of dispersion science and technology (01-02-2012)“…Microemulsion based transdermal therapeutic system (TTS) for nitrendipine was developed and evaluated with the aim to improve bioavailability and further…”
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14
P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions
Published in Drug metabolism and drug interactions (01-12-2010)“…P-Glycoprotein (P-gp), the most extensively studied ATP-binding cassette transporter, functions as a biological barrier by extruding toxic substances and…”
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Enhanced Bioavailability of Buspirone From Reservoir-Based Transdermal Therapeutic System, Optimization of Formulation Employing Box–Behnken Statistical Design
Published in AAPS PharmSciTech (01-06-2010)“…The purpose of the present study was to develop and optimize reservoir-based transdermal therapeutic system (TTS) for buspirone (BUSP), a low bioavailable…”
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Development of bioadhesive buccal tablets for felodipine and pioglitazone in combined dosage form: in vitro, ex vivo, and in vivo characterization
Published in Drug delivery (01-07-2011)“…The purpose of the present research was to develop bioadhesive buccal tablets for Felodipine (FDP) and Pioglitazone (PIO), low bioavailability drugs, in a…”
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Development and in vitro evaluation of buccoadhesive carvedilol tablets
Published in Acta pharmaceutica (Zagreb, Croatia) (01-06-2007)“…Buccoadhesive tablets of carvedilol were prepared using HPMC K4M, HPMC K15M and Carbopol 934 as mucoadhesive polymers. Fifteen formulations were developed with…”
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Role of cyclodextrin complexation in felodipine-sustained release matrix tablets intended for oral transmucosal delivery: In vitro and ex vivo characterization
Published in Pharmaceutical development and technology (01-05-2012)“…The objective of the present research was two-fold: To characterize the produced inclusion complex of felodipine (FDP)-hydroxypropyl-β-cyclodextrin (HPβCD)…”
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Development of ultra fast liquid chromatographic method for simultaneous determination of nitrendipine and carvone in skin diffusate samples
Published in Journal of pharmaceutical and biomedical analysis (05-12-2009)“…A simple and sensitive reverse phase ultra fast liquid chromatographic (UFLC) method for simultaneous determination of nitrendipine and carvone in skin…”
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SIMULTANEOUS DETERMINATION OF GLIMEPIRIDE AND ATORVASTATIN IN HUMAN SERUM BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY: APPLICATION TO PHARMACOKINETIC STUDY
Published in Journal of liquid chromatography & related technologies (15-11-2011)“…A simple and sensitive high performance liquid chromatographic method for simultaneous quantification of glimepiride (GMP) and atorvastatin (ATN) in human…”
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