Successful treatment of postoperative multidrug-resistant Acinetobacter baumannii meningitis by tigecycline

•Post operative meningitis is a severe infection.•A. baumannii is frequently isolated in such infection.•Tigecycline is active against A. baumannii and in combination with others antibiotics is a potential treatment for nosocomial meningitis. Tigecycline is a broad-spectrum antibiotic with activity...

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Bibliographic Details
Published in:	Journal of global antimicrobial resistance. Vol. 5; pp. 62 - 63
Main Authors:	Kooli, Ikbel, Brahim, Hajer Ben, Kilani, Mohamed, Gannouni, Chokri, Aouam, Abir, Toumi, Adnene, Loussaief, Chawki, Hattab, Mohamed nejib, Chakroun, Mohamed
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01-06-2016
Subjects:	Acinetobacter baumannii Acinetobacter baumannii - drug effects Acinetobacter Infections - drug therapy Adult Anti-Bacterial Agents - therapeutic use Colistin Drug Resistance, Multiple, Bacterial Humans Male Meningitis - drug therapy Meningitis - microbiology Microbial Sensitivity Tests Minocycline - analogs & derivatives Minocycline - therapeutic use Nosocomial meningitis Tigecycline Nosocomial meningitis Tigecycline Acinetobacter baumannii
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Summary:	•Post operative meningitis is a severe infection.•A. baumannii is frequently isolated in such infection.•Tigecycline is active against A. baumannii and in combination with others antibiotics is a potential treatment for nosocomial meningitis. Tigecycline is a broad-spectrum antibiotic with activity against multidrug-resistant (MDR) bacteria. It has limited indications. Studies are necessary to elaborate new guidelines. Here we report a case of postoperative MDR Acinetobacter baumannii meningitis treated by tigecycline combined with colimycin for 21 days. The treatment was well tolerated with a favourable outcome. In conclusion, tigecycline was shown to be effective in a case of MDR A. baumannii meningitis.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	2213-7165 2213-7173
DOI:	10.1016/j.jgar.2015.12.003