Search Results - "Ganneru, Brunda"

Persistence of immunity and impact of third dose of inactivated COVID-19 vaccine against emerging variants by Vadrevu, Krishna Mohan, Ganneru, Brunda, Reddy, Siddharth, Jogdand, Harsh, Raju, Dugyala, Sapkal, Gajanan, Yadav, Pragya, Reddy, Prabhakar, Verma, Savita, Singh, Chandramani, Redkar, Sagar Vivek, Gillurkar, Chandra Sekhar, Kushwaha, Jitendra Singh, Mohapatra, Satyajit, Bhate, Amit, Rai, Sanjay Kumar, Ella, Raches, Abraham, Priya, Prasad, Sai, Ella, Krishna

“…This is a comprehensive report on immunogenicity of COVAXIN ® booster dose against ancestral and Variants of Concern (VOCs) up to 12 months. It is well known…”
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Th1 skewed immune response of whole virion inactivated SARS CoV 2 vaccine and its safety evaluation by Ganneru, Brunda, Jogdand, Harsh, Daram, Vijaya Kumar, Das, Dipankar, Molugu, Narasimha Reddy, Prasad, Sai D., Kannappa, Srinivas V., Ella, Krishna M., Ravikrishnan, Rajaram, Awasthi, Amit, Jose, Jomy, Rao, Panduranga, Kumar, Deepak, Ella, Raches, Abraham, Priya, Yadav, Pragya D., Sapkal, Gajanan N., Shete-Aich, Anita, Desphande, Gururaj, Mohandas, Sreelekshmy, Basu, Atanu, Gupta, Nivedita, Vadrevu, Krishna Mohan

“…We report the development and evaluation of safety and immunogenicity of a whole virion inactivated (WVI) SARS-CoV-2 vaccine (BBV152), adjuvanted with aluminum…”
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Phase III Pivotal comparative clinical trial of intranasal (iNCOVACC) and intramuscular COVID 19 vaccine (Covaxin®) by Singh, Chandramani, Verma, Savita, Reddy, Prabhakar, Diamond, Michael S., Curiel, David T., Patel, Chintan, Jain, Manish Kumar, Redkar, Sagar Vivek, Bhate, Amit Suresh, Gundappa, Vivek, Konatham, Rambabu, Toppo, Leelabati, Joshi, Aniket Chandrakant, Kushwaha, Jitendra Singh, Singh, Ajit Pratap, Bawankule, Shilpa, Ella, Raches, Prasad, Sai, Ganneru, Brunda, Chiteti, Siddharth Reddy, Kataram, Sreenivas, Vadrevu, Krishna Mohan

“…One of the most preferable characteristics for a COVID-19 vaccine candidate is the ability to reduce transmission and infection of SARS-CoV-2, in addition to…”
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Protective efficacy of COVAXIN® against Delta and Omicron variants in hamster model by Yadav, Pragya D., Mohandas, Sreelekshmy, Shete, Anita, Sapkal, Gajanan, Deshpande, Gururaj, Kumar, Abhimanyu, Wakchaure, Kundan, Dighe, Hitesh, Jain, Rajlaxmi, Ganneru, Brunda, Yemul, Jyoti, Gawande, Pranita, Vadrevu, Krishna Mohan, Abraham, Priya

“…The immunity acquired after natural infection or vaccinations against SARS-CoV-2 tend to wane with time. Here, we compared the protective efficacy of COVAXIN®…”
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HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice by Kulkarni, Viraj, Rosati, Margherita, Valentin, Antonio, Ganneru, Brunda, Singh, Ashish K, Yan, Jian, Rolland, Morgane, Alicea, Candido, Beach, Rachel Kelly, Zhang, Gen-Mu, Le Gall, Sylvie, Broderick, Kate E, Sardesai, Niranjan Y, Heckerman, David, Mothe, Beatriz, Brander, Christian, Weiner, David B, Mullins, James I, Pavlakis, George N, Felber, Barbara K

“…Viral diversity is considered a major impediment to the development of an effective HIV-1 vaccine. Despite this diversity, certain protein segments are nearly…”
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Epidemiological profile of snake-bite cases from Andhra Pradesh using immunoanalytical approach by Brunda, Ganneru, Sashidhar, R B

“…Snake-bites are the common cause of morbidity and mortality in tropical countries. In India, there are 216 species of snakes, of which only four are venomous…”
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The p40 Subunit of Interleukin (IL)-12 Promotes Stabilization and Export of the p35 Subunit by Jalah, Rashmi, Rosati, Margherita, Ganneru, Brunda, Pilkington, Guy R., Valentin, Antonio, Kulkarni, Viraj, Bergamaschi, Cristina, Chowdhury, Bhabadeb, Zhang, Gen-Mu, Beach, Rachel Kelly, Alicea, Candido, Broderick, Kate E., Sardesai, Niranjan Y., Pavlakis, George N., Felber, Barbara K.

“…IL-12 is a 70-kDa heterodimeric cytokine composed of the p35 and p40 subunits. To maximize cytokine production from plasmid DNA, molecular steps controlling…”
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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: a double-blind, randomised, phase 1 trial by Ella, Raches, Vadrevu, Krishna Mohan, Jogdand, Harsh, Prasad, Sai, Reddy, Siddharth, Sarangi, Vamshi, Ganneru, Brunda, Sapkal, Gajanan, Yadav, Pragya, Abraham, Priya, Panda, Samiran, Gupta, Nivedita, Reddy, Prabhakar, Verma, Savita, Kumar Rai, Sanjay, Singh, Chandramani, Redkar, Sagar Vivek, Gillurkar, Chandra Sekhar, Kushwaha, Jitendra Singh, Mohapatra, Satyajit, Rao, Venkat, Guleria, Randeep, Ella, Krishna, Bhargava, Balram

“…To mitigate the effects of COVID-19, a vaccine is urgently needed. BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine formulated with a toll-like receptor…”
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Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBV152: interim results from a double-blind, randomised, multicentre, phase 2 trial, and 3-month follow-up of a double-blind, randomised phase 1 trial by Ella, Raches, Reddy, Siddharth, Jogdand, Harsh, Sarangi, Vamshi, Ganneru, Brunda, Prasad, Sai, Das, Dipankar, Raju, Dugyala, Praturi, Usha, Sapkal, Gajanan, Yadav, Pragya, Reddy, Prabhakar, Verma, Savita, Singh, Chandramani, Redkar, Sagar Vivek, Gillurkar, Chandra Sekhar, Kushwaha, Jitendra Singh, Mohapatra, Satyajit, Bhate, Amit, Rai, Sanjay, Panda, Samiran, Abraham, Priya, Gupta, Nivedita, Ella, Krishna, Bhargava, Balram, Vadrevu, Krishna Mohan

“…BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine (3 μg or 6 μg) formulated with a toll-like receptor 7/8 agonist molecule (IMDG) adsorbed to alum…”
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Immunogenicity and reactogenicity of an inactivated SARS-CoV-2 vaccine (BBV152) in children aged 2–18 years: interim data from an open-label, non-randomised, age de-escalation phase 2/3 study by Vadrevu, Krishna Mohan, Reddy, Siddharth, Jogdand, Harsh, Ganneru, Brunda, Mirza, Nizam, Tripathy, Virendra Nath, Singh, Chandramani, Khalatkar, Vasant, Prasanth, Siddaiah, Rai, Sanjay, Ella, Raches, Blackwelder, William, Prasad, Sai, Ella, Krishna

“…Despite having milder symptoms than adults, children are still susceptible to and can transmit SARS-CoV-2. Vaccination across all age groups is therefore…”
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The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production by Jalah, Rashmi, Rosati, Margherita, Ganneru, Brunda, Pilkington, Guy R, Valentin, Antonio, Kulkarni, Viraj, Bergamaschi, Cristina, Chowdhury, Bhabadeb, Zhang, Gen-Mu, Beach, Rachel Kelly, Alicea, Candido, Broderick, Kate E, Sardesai, Niranjan Y, Pavlakis, George N, Felber, Barbara K

“…IL-12 is a 70-kDa heterodimeric cytokine composed of the p35 and p40 subunits. To maximize cytokine production from plasmid DNA, molecular steps controlling…”
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IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques by Jalah, Rashmi, Patel, Vainav, Kulkarni, Viraj, Rosati, Margherita, Alicea, Candido, Ganneru, Brunda, von Gegerfelt, Agneta, Huang, Wensheng, Guan, Yongjun, Broderick, Kate E., Sardesai, Niranjan Y, LaBranche, Celia, Montefiori, David C., Pavlakis, George N., Felber, Barbara K.

“…Intramuscular injection of macaques with an IL-12 expression plasmid (0.1 or 0.4 mg DNA/animal) optimized for high level of expression and delivered using in…”
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Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques by Kulkarni, Viraj, Jalah, Rashmi, Ganneru, Brunda, Bergamaschi, Cristina, Alicea, Candido, von Gegerfelt, Agneta, Patel, Vainav, Zhang, Gen-Mu, Chowdhury, Bhabadeb, Broderick, Kate E, Sardesai, Niranjan Y, Valentin, Antonio, Rosati, Margherita, Felber, Barbara K, Pavlakis, George N

“…Abstract Optimized DNA vectors were constructed comprising the proteome of SIV including the structural, enzymatic, regulatory, and accessory proteins. In…”
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Supraphysiological levels of IL-15 accelerate immune reconstitution in lymphopenic mice (134.16) by Bergamaschi, Cristina, Ganneru, Brunda, Rosati, Margherita, Usami, Osamu, Valentin, Antonio, Beach, Rachel, Alicea, Candido, Felber, Barbara, Pavlakis, George

“…Abstract Loss of lymphocytes and T cells are a significant medical problem in AIDS and other immunodeficiencies, as well as after various treatments and…”
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DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques by Kulkarni, Viraj, Rosati, Margherita, Jalah, Rashmi, Ganneru, Brunda, Alicea, Candido, Yu, Lei, Guan, Yongjun, LaBranche, Celia, Montefiori, David C., King, Alan D., Valentin, Antonio, Pavlakis, George N., Felber, Barbara K.

“…Background A desirable HIV vaccine should induce protective long‐lasting humoral and cellular immune responses. Methods Macaques were immunized by env DNA,…”
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HIV-1 p24gag Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice by Kulkarni, Viraj, Rosati, Margherita, Valentin, Antonio, Ganneru, Brunda, Singh, Ashish K., Yan, Jian, Rolland, Morgane, Alicea, Candido, Beach, Rachel Kelly, Zhang, Gen-Mu, Le Gall, Sylvie, Broderick, Kate E., Sardesai, Niranjan Y., Heckerman, David, Mothe, Beatriz, Brander, Christian, Weiner, David B., Mullins, James I., Pavlakis, George N., Felber, Barbara K.

“…Viral diversity is considered a major impediment to the development of an effective HIV-1 vaccine. Despite this diversity, certain protein segments are nearly…”
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PL4-4 Heterodimeric IL-15/IL-15Rα accelerates immune reconstitution in lymphopenic mice by Bergamaschi, Cristina, Ganneru, Brunda, Rosati, Margherita, Usami, Osamu, Valentin, Antonio, Beach, Rachel K., Alicea, Candido, Felber, Barbara K., Pavlakis, George N.

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Quantitation of indian krait (Bungarus caeruleus) venom in human specimens of forensic origin by indirect competitive inhibition enzyme-linked immunosorbent assay by BRUNDA, Ganneru, BEEDU SASHIDHAR RAO, RAJENDRA KUMAR SARIN

“…An indirect competitive inhibition enzyme-linked immunosorbent assay was reported to detect krait venom in human specimens of forensic origin. Polyclonal…”
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IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques by Agneta von Gegerfelt, Wensheng Huang, Yongjun Guan, Barbara K. Felber, Margherita Rosati, Vainav Patel, Celia LaBranche, Rashmi Jalah, Viraj Kulkarni, Kate E. Broderick, Candido Alicea, David C. Montefiori, Brunda Ganneru, George N. Pavlakis, Niranjan Y. Sardesai

“…Intramuscular injection of macaques with an IL-12 expression plasmid (0.1 or 0.4 mg DNA/animal) optimized for high level of expression and delivered using in…”
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HIV-1 p24gag Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice. e60245 by Kulkarni, Viraj, Rosati, Margherita, Valentin, Antonio, Ganneru, Brunda, Singh, Ashish K, Yan, Jian, Rolland, Morgane, Alicea, Candido, Beach, Rachel Kelly, Zhang, Gen-Mu

“…Viral diversity is considered a major impediment to the development of an effective HIV-1 vaccine. Despite this diversity, certain protein segments are nearly…”
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